Clinical trials: Tobacco Abuse
Smoking, Nicotine Dependence
A Brief Dental Office Intervention With Tobacco Quitline
The novel and exploratory nature of this intervention relates to the concept of incorporating patient-specific oral health information obtained during a dental hygiene visit into the tobacco quitline counseling.
- Trial name
- NCT00273156
- Testing
- Telephone quitline
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cancer, Tobacco Use
Improving Tobacco Treatment Rates for Cancer Patients Who Smoke
The research objective is to identify a simple, pragmatic, innovative way of enhancing Tobacco Use Treatment (TUT) rates within oncology.
- Conditions
- Cancer, Tobacco Use, Smoking, Nicotine Dependence
- Trial name
- NCT04738643
- Testing
- Tobacco Use Treatment Service and Varenicline Management
- Where
- 2 sites in United States
- Volunteers
- 685 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Nicotine Dependence
Studying Nicotine Addiction With Transcranial Magnetic Stimulation
Background: Nicotine addiction often makes it difficult to stop smoking. Researchers want to understand the areas of the brain that are important in nicotine addiction.
- Trial name
- NCT01702948
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Use Disorder
Dental Tobacco Control.Net:Improving Practice
This is a randomized, controlled trial (RCT) to test the efficacy of an internet continuing dental education intervention designed to increase tobacco cessation counseling in dental practices.
- Trial name
- DTC (NCT00627185)
- Testing
- Internet-delivered continuing professional development, No intervention arm
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Tobacco Dependence, Schizophrenia
The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Schizophrenia
Cigarette smoking represents a major health problem for patients suffering from schizophrenia. Compared to the general population, schizophrenic patients are significantly more likely to be addicted to nicotine.
- Trial name
- PSIAARP (NCT00495352)
- Testing
- Hihg-doseNRT, Low-dose NRT, bupropion
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- Yu-Li Hospital
Psychiatric Disorders
TORCH - Transdiagnostic Observation of Risk Factors, Craving and Health Behaviours in Psychiatric Patients
Mental disorders are often accompanied by health-risk behaviours, psychiatric comorbidity, and reduced functioning. TORCH investigates transdiagnostic mechanisms underlying multiple health behaviour change in adult psychiatric…
- Trial name
- TORCH (NCT07844798)
- Testing
- person-centred interventions
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Second Hand Tobacco Smoke, Nicotine Dependence
Babies Living Safe and Smokefree
The purpose of this randomized controlled trial is to develop and test the efficacy of a multilevel, multimodal intervention designed to modify maternal smoking behavior to reduce children's exposure to secondhand tobacco smoke…
- Trial name
- BLiSS (NCT02602288)
- Testing
- Ask, Advise, Refer, Telebased tobacco counseling, Telebased nutrition counseling
- Where
- 2 sites in United States
- Volunteers
- 396 people
- Sponsor
- Temple University
Nicotine Dependence
Extended Cessation Treatment for Teen Smokers
This study is designed to test the efficacy of an extended smoking cessation program for teen smokers. We hypothesize that teen smokers randomized to extended treatment will have a higher abstinence rate at 52 week follow-up than…
- Trial name
- Nicoteens (NCT00459953)
- Testing
- Extended treatment
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Stanford University
Nicotine Dependence
Smart Olfaction App to Reduce Relapse
The proposed project aims to refine and test a novel biobehavioral smoking cessation intervention that integrates the strategic application of olfactory stimulation to reduce cigarette craving with an established smartphone-based…
- Trial name
- SOARR (NCT07007195)
- Testing
- Ad Libitum Use followed by Instructed Use of the Inspire Device, Instructed Use followed by Ad Libitum Use of the Inspire Device, Smart-T Smoking Cessation App with the Inspire Device Condition
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Houston
Tobacco Use Disorder
Effect of Transcranial Direct Current Stimulation (tDCS) on Tobacco Consumption
The primary purpose of the protocol is to evaluate the effect of repeated application for 5 consecutive days of a real tDCS compared to the application of a placebo tDCS (sham procedure) on the evolution of tobacco consumption in…
- Trial name
- TABELEC (NCT01930422)
- Testing
- tDCS procedure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Toulouse
Tobacco Use Disorder, Nicotine Addiction
Effects of Semaglutide on Nicotine Intake
Tobacco use remains the foremost cause of preventable deaths in the U.S. and worldwide. Advancing new smoking cessation therapies, including those targeting novel biological mechanisms, is a critical public health priority.
- Trial name
- NCT05530577
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Smoking Cessation
Interventions for Smoking Among Persons in Recovery
Examine the efficacy of a stepped-care smoking cessation intervention for current and former smokers in chemical dependency treatment programs.
- Trial name
- INSPIRE (NCT00714896)
- Testing
- Stepped-Care, Control
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cigarette Smoking, Nicotine Dependence
Effects of Very Low Nicotine Content Cigarettes Among Adults Who Smoke Daily in South Korea
The goal of this clinical trial is to learn how switching to very low nicotine content (VLNC) cigarettes affects smoking behavior and nicotine exposure among adults in South Korea who smoke conventional cigarettes daily.
- Trial name
- NCT07755891
- Testing
- SPECTRUM cigarettes
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sung-il Cho
Tobacco Dependence
Predictors of Treatment Outcome for Smokers With and Without Schizophrenia
The primary purpose of this investigation is to determine the predictive value of task persistence as measured by a mirror tracing task.
- Trial name
- NCT00501007
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Tobacco Use Cessation, Tobacco Use Disorder
Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid
Coal miners in Central Appalachia have among the highest rates of tobacco and nicotine product (TNP) use of any occupational group and face elevated rates of lung cancer and coal workers' pneumoconiosis ("black lung").
- Conditions
- Tobacco Use Cessation, Tobacco Use Disorder, Nicotine Dependence, Smokeless Tobacco Use
- Trial name
- NCT07694492
- Testing
- QuitAid (pharmacist-delivered MTM), Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Nicotine Dependence
NeuroControl of Nicotine Dependence
The purpose of the study is to examine the effects of continuous theta burst stimulation (cTBS) on different forms of cognitive control in adults who smoke cigarettes, and to determine if the location where cTBS is delivered may…
- Trial name
- NCT06347055
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Alcohol Use Disorder, Hiv
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2
This study seeks to determine the feasibility, acceptability, and preliminary efficacy of an intervention consisting of off-label use of a medication with strong efficacy data for alcohol use disorder (AUD) with medical…
- Conditions
- Alcohol Use Disorder, Hiv, Tobacco Use Disorder
- Trial name
- HARP (NCT06006143)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Nicotine Addiction
Investigation of Cycloserine as a Smoking Cessation Treatment
Psychosocial treatments for drug abuse benefit some patients (Rawson et al 2004), but there is an urgent need for new treatment approaches that can improve treatment outcomes.
- Trial name
- NCT01062932
- Testing
- Cycloserine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Baylor College of Medicine
Nicotine Dependence, Nicotine Addiction
Effectiveness of N-Acetylcysteine (NAC) in Motivational Enhancement Therapy for Nicotine Addiction
The goal of this clinical trial is to determine the effectiveness of the combination of n-acetylcysteine and motivational enhancement therapy on laboratory improvement in the form of changes in blood nicotine, radiological…
- Trial name
- NCT05903014
- Testing
- n-acetylcysteine, Motivational Enhancement Therapy
- Where
- Indonesia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Tobacco Abuse Smoke
CogEcig: Cognitive Functioning and Electronic Cigarette
The aim of the present study is to compare cognitive scores (attention, executive function and working memory) of different e-Cigarette strength with usual cigarettes.
- Trial name
- CogEcig (NCT01735487)
- Testing
- Own Brand cigarette, one high 2,4% nicotine, original 7,4 mg nicotine
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Catania
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