Clinical trials: Tobacco Consumption
Smoking &Amp; Tobacco Cessation
An Innovative Conversational Agent (Quitbot) for Smoking Cessation
This phase III trial compares two remote digital smoking cessation programs to see how well they work for quitting smoking.
- Trial name
- NCT04308759
- Testing
- Experimental Smoking Cessation Program, Control Smoking Cessation Program
- Where
- United States
- Volunteers
- 1,647 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Tobacco Smoking
Cognitive and Emotional Skills to Aid Smoking Prevention
The purpose of the current proposal is to investigate the extent to which interventions designed to improve cognitive (working memory) and emotional (distress tolerance) regulatory processes enhance the effectiveness of standard…
- Trial name
- DOAN (NCT03058991)
- Testing
- Distress Tolerance Intervention, Working Memory Intervention, Control Informational Intervention
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Tobacco Use Disorder
Persistence-Targeted Smoking Cessation
The investigators propose to develop a theory-based smoking cessation intervention (called Persistence-targeted smoking cessation; PTSC).
- Trial name
- PTSC (NCT01654107)
- Testing
- Persistence Targeted Smoking Cessation, Clearing The Air, Nicotine lozenge
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Smoking
Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT)
The purpose of this research study is to: 1. compare the effectiveness of a nicotine patch and nicotine nasal spray for smoking cessation; and 2.
- Trial name
- NCT00326781
- Testing
- Nicoderm Transdermal Patch, Nicotine Nasal Spray
- Where
- United States
- Volunteers
- 674 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Use Disorder
Evaluation of Oral Tobacco as a Harm Reduction Method for Smokers
Recently, tobacco companies have developed new oral tobacco products that are purportedly less harmful than conventional tobacco products.
- Trial name
- NCT00711100
- Testing
- Camel Snus, Marlboro Snus, Stonewall
- Where
- 2 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence, Nicotine Addiction
A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults
Almost one in ten young adults report current e-cigarette use, putting them at risk of developing nicotine addiction and long-term health effects of exposure to inhaled toxicants.
- Conditions
- Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping
- Trial name
- NCT05897242
- Testing
- Smartphone app, Text Message, Survey Administration
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Tobacco Use, Tobacco Smoking
Tobacco Cessation at FDNY
At the Fire Department of the City of New York (FDNY) World Trade Center Health Program, 36% of participants in the low dose computed tomography (LDCT) lung cancer screening program are current smokers, despite referral to the…
- Conditions
- Tobacco Use, Tobacco Smoking, Tobacco Use Cessation
- Trial name
- NCT05997225
- Testing
- opt out enrollment, tailored counseling, varenicline started prior to target quit date, opt in enrollment, non-tailored counseling, varenicline started prior to target quit date
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Tobacco Dependence
Low Nicotine Cigarettes Plus Electronic Cigarettes
This study aims to determine the health effects of very low nicotine content in cigarettes, in conjunction with the availability of nicotine-containing electronic cigarettes (e-cigs) among smokers with mental health conditions…
- Trial name
- NCT04058717
- Testing
- Normal Nicotine Content research cigarettes, High Nicotine e-cigarette, Very Low Nicotine Content research cigarettes
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Alcohol Use Disorder, Cigarette Smoking
Semaglutide for Alcohol Use Disorder
This is an early-Phase II human laboratory trial using a randomized, placebo-controlled, dose-ranging design to investigate the effects of semaglutide, a GLP-1 receptor agonist, on alcohol-related outcomes in adults with alcohol…
- Trial name
- NCT05520775
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Insomnia, Nicotine Dependence
Study of Lunesta Versus Placebo for Sleep Problems Related to Smoking Cessation and Zyban
Objectives: The primary objective of this study is to determine the efficacy of eszopiclone at treating sleep problems related to withdrawal from nicotine in healthy smokers attempting smoking cessation.
- Trial name
- NCT00511134
- Testing
- Eszopiclone, Bupropion
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking, Cigarette
Perceptions of Cigarette Smoking in Young Adults
This study focuses on menthol (n = 125) and non-menthol (n = 125) smoking young adults (YAs; defined here as ages 18 to 26).
- Trial name
- PRISM (NCT03953508)
- Testing
- Cigarette flavor type
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Little Cigars and Cigarillos (LCC) Use
Little Cigar and Cigarillo Warnings for Youth
This study explores the effect of the little cigars and cigarillos (LCC) warnings on youth who currently use, have ever used, or are susceptible to using LCCs.
- Trial name
- NCT06413797
- Testing
- FDA warnings + Image, FDA Warnings Text-Only, Surgeon General Text-Only Warnings
- Where
- United States
- Volunteers
- 928 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cannabis Use Disorder, Tobacco Use Disorder
Clinical Trial Tobacco Marijuana
Approximately 50% of persons seeking treatment for cannabis-use disorders (CUDs) regularly smoke tobacco. Combining tobacco with cannabis has become a common method of smoking cannabis.
- Trial name
- RCTTM (NCT02277665)
- Testing
- CUD Treatment, Tobacco Treatment
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Smoking Cessation
Treatment of Smoking Lapses and Relapses
Many smokers who try to stop smoking with nicotine medications (NM) such as gum, lozenge and patch, go back to smoking (i.e., a slip or lapse).
- Trial name
- NCT01807871
- Testing
- nicotine patch, experimental use, nicotine patch, labeled use
- Where
- United States
- Volunteers
- 701 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Tobacco Smoking, Smoking Behaviors
Human Perception of Odors and Odor Blockers
The goal of this clinical trial is to determine whether blockers of perception of key odorants in cigarette smoke have any utility in smoking cessation.
- Trial name
- NCT06191419
- Testing
- Odorants
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Tim McClintock
Smoking Cessation
Advancing Tobacco Use Treatment for African American Smokers
The purpose of this study is to examine whether or not providing Chantix (varenicline) will help African American smokers quit smoking.
- Trial name
- KIS-IV (NCT02360631)
- Testing
- Chantix
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Lisa Sanderson Cox, PhD
Anxiety Disorders, Depression
Personalized Feedback for Distress Intolerant Smokers
This project will develop and refine a computer-delivered integrated Personalized Feedback Intervention (PFI) that directly addresses smoking and distress tolerance.
- Conditions
- Anxiety Disorders, Depression, Psychological Distress, Tobacco Dependence
- Trial name
- NCT03918031
- Testing
- PFI for Smoking & Distress Tolerance, PFI for Smoking Only
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Houston
Tobacco Use, E-Cigarette Use
E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease
This study is designed to enhance the understanding of the possible health effects of e-cigarette use by relating the acute and long-term use of e-cigarettes and conventional cigarettes ("products") to well-validated…
- Conditions
- Tobacco Use, E-Cigarette Use, Cardiovascular Diseases, Pulmonary Disease
- Trial name
- NCT03863509
- Testing
- Cigarettes, E-Cigarettes
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Nicotine Dependence, Cigarettes
Penn State TXT2Quit Study
This study is evaluating the feasibility and short term smoking cessation outcomes of an automated smoking cessation intervention delivered via mobile phone text messaging as an adjunct to Varenicline in a primary care setting.
- Trial name
- NCT02367391
- Testing
- Motivational Text Messages, Control
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Smoking, Cigar
Cigarillo Warnings Image Sorting Study
The goal of this study is to examine the impact of repeated exposure to cigarillo warnings on cigarillo users' intentions and behaviors for cigarillo smoking.
- Trial name
- NCT05838378
- Testing
- Package image sorting with pictorial warnings, Package image sorting with Surgeon General text-only warnings, Package image sorting with FDA text-only warnings
- Where
- United States
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- Boston University