Clinical trials: Tobacco Prevention
Tobacco Use Disorder
Zileuton With or Without Celecoxib As Chemopreventive Agents in Smokers
The goal of this clinical research study is to learn how zileuton alone or the combination of zileuton and celecoxib may affect certain chemicals in the body that may be linked with a risk for smoking-related lung disease.
- Trial name
- NCT01021215
- Testing
- Zileuton, Celecoxib, laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- National Cancer Institute (NCI)
Cigarette Smoking
Improving the Delivery of Smoking Cessation Guidelines in Hospitalized Veterans
The primary objective of this study is to determine whether a nurse-initiated intervention, which couples brief inpatient counseling and proactive telephone counseling by a centralized tobacco quitline, improves 6-month cessation…
- Trial name
- NCT00816036
- Testing
- Smoking Cessation Guideline Implementation
- Where
- 4 sites in United States
- Volunteers
- 898 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Smoking Cessation, Alcohol Consumption
Smoking Cessation in Alcoholics
Most alcohol-dependent individuals are heavy smokers. The aim of this study is to evaluate whether a specific smoking cessation program (based on cognitive-behavioral therapy) for inpatient alcohol-dependent smokers is more…
- Trial name
- NCT00963482
- Testing
- Cognitive-behavioural smoking cessation program, Autogenic training
- Where
- Switzerland
- Volunteers
- 103 people
- Sponsor
- University Hospital, Basel, Switzerland
Tobacco Smoking
Cognitive and Emotional Skills to Aid Smoking Prevention
The purpose of the current proposal is to investigate the extent to which interventions designed to improve cognitive (working memory) and emotional (distress tolerance) regulatory processes enhance the effectiveness of standard…
- Trial name
- DOAN (NCT03058991)
- Testing
- Distress Tolerance Intervention, Working Memory Intervention, Control Informational Intervention
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Tobacco Use Disorder
Progesterone for Smoking Relapse Prevention Following Delivery
Smoking is the main preventable cause of mortality in Western countries, contributing to over 430,000 deaths a year in the U.S. alone.
- Trial name
- NCT01972464
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Yale University
Nicotine Dependence
Effectiveness of GSK598809, a Selective D3 Antagonist, Added to CBT and NRT for Smoking Cessation and Relapse Prevention
The purpose of this research study is to find out if an investigational drug, GSK598809 can help people who have very recently quit smoking; the investigators want to find out if continuing to take GSK598809 over six weeks can…
- Trial name
- NCT01188967
- Testing
- GSK598809
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Massachusetts General Hospital
Nicotine Dependence
Study Two on the Effectiveness of Mindfulness Training for Smokers
The MTS2 study enrollment goal is N=240 adult smokers randomized to study treatments. The study design includes two randomized arms to compare matched intensive interventions and a third non-randomized option for participants who…
- Trial name
- MTS2 (NCT01299909)
- Testing
- Integrated Training for Smokers, Mindfulness Training for Smokers, Quitline
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of Wisconsin, Madison
Adolescent Behavior, Tobacco Use
Pittsburgh and Rural Area High School Tobacco Prevention
This research project will explore the feasibility and acceptability of a web-based media literacy tobacco prevention program. The project will be conducted with 9th graders in two schools in the Pittsburgh area.
- Conditions
- Adolescent Behavior, Tobacco Use, E-Cig Use
- Trial name
- NCT05081843
- Testing
- AD IT UP media literacy intervention, Usual health education curriculum
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Prescription Drug Abuse, Substance Abuse
A High School Program for Preventing Prescription Drug Misuse
This project will develop and evaluate a program to prevent prescription drug misuse in high school students
- Conditions
- Prescription Drug Abuse, Substance Abuse, Substance Use (Drugs, Alcohol)
- Trial name
- NCT03219190
- Testing
- LST High School Hybrid
- Where
- United States
- Volunteers
- 1,804 people, healthy volunteers welcome
- Sponsor
- National Health Promotion Associates, Inc.
Little Cigars and Cigarillos (LCC) Use
Little Cigar and Cigarillo Warnings for Youth
This study explores the effect of the little cigars and cigarillos (LCC) warnings on youth who currently use, have ever used, or are susceptible to using LCCs.
- Trial name
- NCT06413797
- Testing
- FDA warnings + Image, FDA Warnings Text-Only, Surgeon General Text-Only Warnings
- Where
- United States
- Volunteers
- 928 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Smoking Among Youth
Hutchinson Smoking Prevention Project
The Hutchinson Smoking Prevention Project is a 16-year, group-randomized trial to determine the extent to which a school-based (grades 3-10), theory-based, social-influences tobacco use prevention intervention can deter youth…
- Trial name
- HSPP (NCT00115869)
- Testing
- Social-influences
- Where
- United States
- Volunteers
- 8,388 people
- Sponsor
- Fred Hutchinson Cancer Center
Tobacco Use Cessation, Cancer Prevention
Project Impact 2: A Culturally Tailored Smoking Cessation Intervention for Latino Smokers
The goal of this research study is to learn how 3 different kinds of counseling treatments may help individuals to quit smoking.
- Trial name
- NCT02596711
- Testing
- Nicotine Patch, Questionnaires, Carbon Monoxide (CO) Test
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Vaping Behavior
Impact of E-Cigarette Prevention Messages on Adolescents
The purpose of this trial is to determine whether a vaping prevention text message program reduces susceptibility to vaping among adolescents and young adults.
- Trial name
- NCT05985538
- Testing
- Vaping prevention text messages, Wellness behaviors text messages
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Nicotine Dependence
Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking
The purpose of this study is to evaluate the efficacy of the glycine antagonist, GW468816, compared with placebo on duration of abstinence and rates of relapse in recently quit female smokers in a randomized, double-blind…
- Trial name
- NCT00218465
- Testing
- GW468816
- Where
- 2 sites in United States
- Volunteers
- 264 people
- Sponsor
- Massachusetts General Hospital
Alcohol Drinking, Smoking
An Effectiveness Trial of Project ALERT
The purpose of this study is to replicate a longitudinal evaluation of Project ALERT, a substance abuse prevention program that targets middle school students.
- Conditions
- Alcohol Drinking, Smoking, Marijuana Smoking
- Trial name
- NCT00650585
- Testing
- Project ALERT
- Where
- United States
- Volunteers
- 8,338 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Smoking, Cigarette, Breastfeeding
Postpartum Smoking Relapse Prevention by Breastfeeding Promotion
This is a randomized controlled trial to prevent postpartum smoking relapse by breastfeeding promotion. The intervention group (N=30) will receive multicomponent breastfeeding intervention from late pregnancy to 6 months…
- Trial name
- NCT04670822
- Testing
- Breastfeeding promotion
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Tobacco Use Behavior
Smoking Prevention Through Social Connections Among Adolescents - ASPIRE
The central hypothesis of this study is that the addition of social influence strategies to a web-based program called ASPIRE will boost its success in lowering intention to use tobacco among adolescents and experiencing stronger…
- Trial name
- NCT02703597
- Testing
- Surveys, ASPIRE, GSA-ASPIRE-Network
- Where
- United States
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- University of Florida
Smoking, Cigarette, Breastfeeding
Lung and Breast Cancer Prevention by an Integrated Intervention of Maternal Smoking Cessation and Breastfeeding
This pilot clinical trial aims to integrate maternal smoking cessation and breastfeeding interventions to enhance both cancer prevention behaviors.
- Trial name
- NCT05123118
- Testing
- Integrated intervention of smoking cessation and breastfeeding
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xiaozhong Wen
ADHD
Prevention of Cigarette Smoking in Attention Deficit Hyperactivity Disorder (ADHD) Youth With Concerta
This study will consist of a six-week open-label treatment period with an extended duration methylphenidate (OROS MPH) followed by subsequent monthly visits for 24 months in a large sample of youths aged 12-17 who meet Diagnostic…
- Trial name
- NCT00181714
- Testing
- methylphenidate HCl (Concerta)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Massachusetts General Hospital
Tobacco Use
Expanding the Click City Tobacco Prevention Program to Include E-cigarettes and Other Novel Tobacco Products
The goal of this study is to modify a smoking prevention program for 5th and 6th grade students to also target vaping e-cigarettes.
- Trial name
- NCT03682900
- Testing
- Click City®: Tobacco, Usual Tobacco Curriculum
- Where
- United States
- Volunteers
- 2,673 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.