Clinical trials: Tobacco Product
Initial Efficacy of Quit Line, Efficacy of Secondary Reengagement Intervention
Enhancing the Efficacy of Smoking Quit Line in the Military (AFIII Renewal)
This study is a randomized clinical trial designed to measure the effectiveness of three QL interventions for smokers who failed to quit an initial smoking cessation intervention, but remain motivated to quit smoking.
- Trial name
- Freedom (NCT02201810)
- Testing
- Rate reduction intervention, Recycling Group, Choice Group
- Where
- United States
- Volunteers
- 614 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Tobacco Use Disorder
Zileuton With or Without Celecoxib As Chemopreventive Agents in Smokers
The goal of this clinical research study is to learn how zileuton alone or the combination of zileuton and celecoxib may affect certain chemicals in the body that may be linked with a risk for smoking-related lung disease.
- Trial name
- NCT01021215
- Testing
- Zileuton, Celecoxib, laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- National Cancer Institute (NCI)
High-risk Lung Nodules
Immunoprevention for High-risk Lung Lesions
The main purpose of this study is to assess nadunolimab as an immunoprevention strategy for high-risk lung nodules in participants who are current or former tobacco smokers. The study may last up to 5 years for each participant.
- Trial name
- NCT07284485
- Testing
- Nadunolimab
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Robert Samstein
Cigarillo Flavor
Attitudes and Perceptions Attitudes and Smoking Perceptions in the Real Environment -II
This multi-method project will recruit young adults who currently use cigarillos and examine the effects of different flavored cigarillo types (concept, characterizing, tobacco) on three measures of tobacco product appeal…
- Trial name
- ASPIRE-II (NCT06668350)
- Testing
- Smoking outcomes
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking, Tobacco, Vaping
Investigating Exposure to Toxicants From Smoking and Vaping
Background: Many people who smoke use vaping products to help them quit. Levels of toxicants in urine samples are substantially lower in those who exclusively vape compared to those who smoke, suggesting that vaping poses only a…
- Conditions
- Smoking, Tobacco, Vaping, Mental Health Disorder
- Trial name
- NCT05953220
- Testing
- Exclusive tobacco smoking, Exclusive e-cigarette use, Dual use of e-cigarettes and tobacco smoking
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King's College London
Marijuana Smoking, Cannabis
Study on Regulated Cannabis Sales in Pharmacies
Though regulated cannabis sales are increasing, little is known about the individual health effects of cannabis regulation. Data from countries with a regulated market can be used to test the effect of regulation on the price of…
- Conditions
- Marijuana Smoking, Cannabis, Cannabis Use
- Trial name
- SCRIPT (NCT06120855)
- Testing
- Regulated cannabis from authorized pharmacies, Cannabis from the illicit market
- Where
- 2 sites in Switzerland
- Volunteers
- 1,177 people, healthy volunteers welcome
- Sponsor
- University of Bern
Cardiovascular Health, Self-management
MECA Clinical Intervention ( MECA Health360x)
The purpose of this research is to test whether a technology application(Health360x) that lets participants set goals for better health and track health can help participants reduce their heart disease risk.
- Trial name
- MECAH360x (NCT04791618)
- Testing
- Health360x plus health coach, Health360x only (High tech)
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Smoking Cessation
Pharmacological Aids for Interactive Smoking Cessation
There is an important need for effective smoking cessation programs that both (a) promote the effective use of pharmacological aids, such as nicotine replacement products and bupropion, and (b) provide cognitive-behavioral…
- Trial name
- NRT_2 (NCT02329249)
- Testing
- Smokefree Partners: 21 Days to Freedom, Wait-List Control
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Tabagism
Prevention in a Virtual Community Game
The main objective of the SCOTT project is to reduce tobacco experimentation of teenagers through an online intervention based on social networking and empowerment of users. Specific objectives of this emerging project are : 1.
- Trial name
- SCOTT (NCT04888208)
- Testing
- Behavioral
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Cancer, Precancerous Condition
Green Tea Extract in Treating Current or Former Smokers With Bronchial Dysplasia
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of Polyphenon E, a substance found in green tea, may keep cancer from forming in current or former smokers with bronchial dysplasia.
- Conditions
- Lung Cancer, Precancerous Condition, Tobacco Use Disorder
- Trial name
- NCT00611650
- Testing
- defined green tea catechin extract
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- British Columbia Cancer Agency
Tobacco-Related Carcinoma
Oral Nicotine Product Messaging to Communicate Risk of Use for Young Adults
This clinical trial tests the effect of different types of oral nicotine pouch (ONP) messaging to communicate risk of using these products for young adults.
- Trial name
- NCT07702435
- Testing
- Behavioral Intervention, Survey Administration
- Where
- United States
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Smoking Cessation
Countering Young Adult Tobacco Marketing in Bars
The goal of the study is to implement and evaluate interventions to decrease smoking among young adults attending bars and nightclubs.
- Trial name
- NCT01686178
- Testing
- Anti-smoking social marketing campaign
- Where
- United States
- Volunteers
- 17,422 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking, Tobacco
Nicotine Pharmacokinetics of THS Single Use of a Regular or a Menthol Stick Compared to CIG
The purpose of this study was to describe the nicotine pharmacokinetic (PK) profile during and after single use of THS (Induction heating technology, with either a regular or menthol stick) compared to singular CIG smoking in…
- Trial name
- NCT05789420
- Testing
- P1R stick, P1M stick, CIG
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Major Depression, Tobacco Addiction
Transcranial Magnetic Stimulation in Patients with Dual Disorders
According to the WHO, 280 million people are diagnosed with depression, the prevalence of which is almost twice as high in women as in men, with the incidence among young people increasing in recent years.
- Trial name
- NCT06765824
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Cardenal Herrera University
Nicotine Dependence, E-Cig Use
Research and Innovation to Stop E-cigarette/Vaping in Young Adults
The aim of this study is to test intervention components to help young adults quit vaping. A 2x2 factorial design will be used where all participants receive quitline-delivered behavioral phone counseling, and components to be…
- Trial name
- (RISE) (NCT04974580)
- Testing
- Nicotine patch, Phone Counseling, Digital Coaching
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Smoking Cessation, Smoking, Cigarette
Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia
The goal of this clinical trial is to evaluate the effectiveness and implementation of a pharmacist-delivered MTM (medication therapy management) approach, called QuitAid, to quitting cigarette smoking in rural Appalachia.
- Conditions
- Smoking Cessation, Smoking, Cigarette, Smoking Reduction, Smoking
- Trial name
- NCT05660525
- Testing
- 4 weeks of Nicotine lozenge, 8 weeks of Nicotine Replacement Therapy Patch, QuitAid
- Where
- United States
- Volunteers
- 768 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Cigarette Smoking
Project 1, Study 2: The Combined Impact of Nicotine Replacement and Spectrum Cigarettes
Project 1, Study 2 will evaluate the impact of very low nicotine content cigarettes with and without transdermal nicotine on cigarettes smoked per day, nicotine exposure, discomfort/dysfunction, other health-related behaviors…
- Trial name
- NCT02301325
- Testing
- Smoking research cigarettes with or without NRT
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Wake Forest University Health Sciences
Smoking, Smoking Cessation
BRP1802 Smoking Abstinence Study
A single-center study designed to evaluate changes in short-term biomarkers of potential harm (BoPH) in healthy adult cigarette smokers of two age groups (Group A: 24-34 years; Group B: 35-60 years) during 14 days of smoking…
- Conditions
- Smoking, Smoking Cessation, Tobacco Use
- Trial name
- NCT04979013
- Testing
- Smoking Abstinence
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Tobacco Use Cessation
Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)
The over-arching research question is: Does message (Advise) and referral approach (Refer) influence a patient's willingness to "opt-in" to receive a call from an Illinois Tobacco Quitline (ITQL) smoking cessation coach in…
- Trial name
- NCT04827420
- Testing
- Mi Quit Care
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Smoking Cessation, Smoking, Tobacco
Path2Quit Tobacco Intervention For African Americans
The purpose of this research is to study a smoking cessation program for adult smokers in Northeast Ohio. The study will also look at how different people respond to the program.
- Trial name
- NCT03524482
- Testing
- SmokeFreeText, Path2Quit
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center