Clinical trials: Tobacco Smoking
Smoking Cessation
Post-Discharge Smoking Cessation Strategies: Helping HAND 4
This randomized controlled trial will compare the effectiveness of two models of post-discharge tobacco cessation treatment for adult smokers admitted to 3 U.S. hospitals.
- Trial name
- HH4 (NCT03603496)
- Testing
- Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
- Where
- 3 sites in United States
- Volunteers
- 1,416 people
- Sponsor
- Massachusetts General Hospital
Cough
Effect of Electronic Cigarette Use on Cough Reflex Sensitivity
Although electronic cigarettes (e-cigs) are now widely used, very little information exists regarding the effect of electronic cigarette use (vaping) on the respiratory system.
- Trial name
- NCT02203162
- Testing
- electronic cigarette exposure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Smoking
Protecting the 'Hood Against Tobacco
Among all racial/ethnic groups, African Americans have the greatest risk of becoming ill or dying from tobacco-related diseases.
- Trial name
- NCT00187603
- Testing
- tobacco cessation program
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation, Diabetes Type 2
Diabetes and Smoking Cessation: a Gender-Oriented Study
People with diabetes still smoke at equivalent rates as non-diabetics. There is lack of evidence regarding interventions for smoking cessation among individuals with diabetes.
- Trial name
- DiSCGO (NCT03426423)
- Testing
- Behavioral smoking cessation intervention, Control
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Carole Clair
Chronic Coronary Insufficiency, Smoking
Coagulation Profile in Patients Undergoing Coronary Angiography and Percutaneous Coronary Intervention
The activated clotting time (ACT), global thrombosis test (GTT-3), platelet inhibition P2Y12 (VerifyNow) test and serum coagulation factors will be measured in patients undergoing coronary angiography (CA) and percutaneous…
- Trial name
- GlobalACT (NCT05336669)
- Volunteers
- 40 people
- Sponsor
- Centre of Postgraduate Medical Education
Tobacco Products, Smoking Behavior
Communicating About Nicotine Reduction in Cigarettes
The goal of this clinical trial is to learn how a messaging campaign about reduced nicotine cigarettes and policy, combined with the use of very low nicotine cigarettes (VLNCs), affects smoking behavior and attitudes among adult…
- Conditions
- Tobacco Products, Smoking Behavior, Cigarette Use
- Trial name
- NCT06787937
- Testing
- VLNC messages, Control message
- Where
- 2 sites in United States
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Nicotine Addiction
Quantitation of Human Cerebral Nicotinie Receptors With 2[18F]FA-85380 and PET Healthy Non-smokers and Ex-Smokers and in Heavy and Light Situational Smokers
Background: Central nicotinic acetylcholine receptors (nAChRs) are primary targets for the action of nicotine. In addition to being involved in tobacco dependence, they are also involved in a variety of brain disorders, including…
- Trial name
- NCT01038245
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking
Tobacco Cessation Via Public Health Dental Clinics
The study will examine the effectiveness of public health dental practitioners using a brief office based intervention designed to help patients quit smoking or smokeless tobacco use, as compared to usual care.
- Trial name
- PHD2 (NCT00683839)
- Testing
- Brief tobacco counseling
- Where
- 3 sites in United States
- Volunteers
- 2,637 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Smoking Cessation
Adaptive Mobile Interventions to Reduce Cancer Risk Behaviors
Tobacco use remains the leading cause of preventable death, causing over 400,000 annual deaths in the United States alone. Smartphone-based interventions, particularly those leveraging real-time adaptive messaging, represent a…
- Trial name
- NCT07585357
- Testing
- Smartphone-based intervention messages
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Hookah Smoking
Effects of Hookah Smoking on Blood Flow to the Heart, Muscle and Skin
This is a pilot study on acute effects of Hookah smoking on the sympathetic neural control of the human cardiovascular system. Hookah smoking is known to transiently increase blood pressure and heart rate while decreasing heart…
- Trial name
- NCT02147665
- Testing
- Hookah smoking
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Smoking Cessation
Factorial Design to Assess Quit-line Connections
Improved strategies and scalable interventions to engage low-socioeconomic status (SES) smokers in tobacco treatment are needed.
- Trial name
- NCT03760107
- Testing
- Connect Smokers to Treatment 1, Connect Smokers to Treatment 2, Connect Smokers to Treatment 3
- Where
- United States
- Volunteers
- 3,723 people
- Sponsor
- Minnesota Department of Health
Menstrual Cycle
Menstrual Phase and Smoking Cessation at a State Quitline
Quitlines are efficient and cost-effective treatments for smoking cessation, yet little research has explored how to personalize and optimize quitline services for women.
- Trial name
- Project Phase (NCT03908320)
- Testing
- Menstrual Cycle Timing, NRT Patch, Cessation Counseling
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Tobacco Use Cessation, Tobacco Smoking
EHR-Based and Fax-Based Referral to a Tobacco Quitline: A Comparative Study
This study is designed to assess whether completely electronic, HIPAA-compliant, EHR-based, closed-loop referrals for tobacco cessation from primary care clinics to a state telephone tobacco quitline service can increase the…
- Trial name
- NCT02735382
- Testing
- Tobacco quitline EHR referral, Tobacco quitline Fax referral
- Where
- United States
- Volunteers
- 14,930 people
- Sponsor
- University of Wisconsin, Madison
Health Communication, Smoking
Messages About Reduced Nicotine in Combusted Tobacco Products
The investigators will conduct a message-exposure experiment with nationally representative samples of smokers, dual-users (cigarettes and e-cigarettes), and young adult non-smokers (aged 18-29).
- Conditions
- Health Communication, Smoking, Smoking, Tobacco, Smoking Behaviors
- Trial name
- NCT05506046
- Testing
- Reduced nicotine message exposure, Modified risk message exposure, Combined message exposure (reduced nicotine + modified risk)
- Where
- United States
- Volunteers
- 1,901 people
- Sponsor
- Georgia State University
Smoking
Does CERC-501 Attenuate Stress-precipitated Smoking Lapse?
A Randomized, Double-Blind, Placebo-Controlled, Crossover Design Study of CERC-501 in a Human Laboratory Model of Stress-precipitated Smoking Behavior.
- Trial name
- NCT02800928
- Testing
- CERC-501
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Yale University
Chronic Obstructive Pulmonary Disease (COPD)
Cross-Sectional Study of COPD Prevalence Among Smokers, Ex-smokers and Never-Smokers in Almaty, Kazakhstan
The purpose of this study is to assess the prevalence of COPD among individuals aged 35 - 59 years based results of spirometry before and after bronchodilator, presence of structural changes in lungs (emphysema, inflammatory…
- Trial name
- NCT02926534
- Where
- Kazakhstan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Kazakhstan Academy of Preventive Medicine
Chronic Airflow Obstruction
A Study on Smoking-related Lung Function Abnormalities and Correlation With Serum Biomarkers in Chinese
Tobacco-smoking causes lung function decline with airflow obstruction, which may be accelerated in persistent smokers.This would eventually lead to chronic obstructive pulmonary disease (COPD), a leading cause of morbidity and…
- Trial name
- NCT01185652
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- The University of Hong Kong
Smokers
Effect of Smoking on Retinal Vessel Morphology and Functionality
The study aims at evaluating the effect of smoking activity on anatomy and functionality of retinal blood vessels using optical coherence tomography angiography (OCT-A) and dynamic vessel analysis (DVA).
- Trial name
- NCT07261176
- Testing
- Cigarette Smoking
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Obstructive Sleep Apnea, Obesity
Impact of Smoking, Benzodiazepine (BZD) Use and Obesity on Severe Obstructive Sleep Apnea (sOSA)
In this study the investigators will analyze the influence of smoking, benzodizepine use, and obesity among patients with severe Obstructive Sleep Apnea (sOSA).
- Conditions
- Obstructive Sleep Apnea, Obesity, Smoking
- Trial name
- NCT02539264
- Testing
- Smoking, Obesity, Benzodiazepine use
- Volunteers
- 920 people
- Sponsor
- Astes
Smoking Cessation, Smoking
A Comparative Effectiveness & Long Term Health Study in Wisconsin Smokers
The overall purpose of this research is two-fold. First, the two smoking cessation medication treatments with the strongest evidence of effectiveness have never been directly compared.
- Conditions
- Smoking Cessation, Smoking, Nicotine Dependence
- Trial name
- NHLBI-RO1 (NCT01553084)
- Testing
- Varenicline, Nicotine lozenge, Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 1,086 people
- Sponsor
- University of Wisconsin, Madison
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