Clinical trials: Tobacco Smoking
Emphysema
Smoking Cessation and Functional CT Assessment
The investigators will study the effect of pulmonary arterial vasodilation to see if it eliminates indices of persistent lung injury in smokers that are susceptible to emphysema.
- Trial name
- NCT03382106
- Testing
- Sildenafil 20 MG, Pulse wave velocity, Carotid artery compliance and stiffness
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Eric A. Hoffman
Smoking, Nicotine Addiction
The END Perioperative Smoking Pilot Study
The purpose of this pilot randomized trial is to determine the feasibility of e-cigarettes and telephone counselling (compared to transdermal nicotine replacement and telephone counselling) as a harm-reduction tool that may lead…
- Conditions
- Smoking, Nicotine Addiction, Surgery
- Trial name
- NCT02482233
- Testing
- ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Tobacco Use, Nicotine Pouch Self-Administration
Comparison of Demand and Substitution for Nicotine Pouches as a Function of Nicotine Dosage
Smoking is a prominent public health issue. Traditional nicotine replacement therapy suffers from being a poor substitute for cigarettes.
- Trial name
- NCT07213947
- Testing
- Nicotine Pouch Dosage
- Where
- United States
- Volunteers
- 1,360 people
- Sponsor
- William Middleton
Schizophrenia, Cigarette Smoking
Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia
This study is designed to evaluate if a treatment the investigators call iCOMMIT is effective at helping smokers with schizophrenia stop smoking.
- Trial name
- NCT02420015
- Testing
- Nicotine replacement therapy, Bupropion, cognitive-behavioral smoking cessation counseling
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Duke University
Substance Use
Substance Use Screening Among Drug User
The purpose of this research is to improve the ability of primary medical staffs in screening and intervention for alcohol, benzodiazepines, and other illicit drug use.
- Trial name
- NCT02951858
- Testing
- Intervention Group, Control Group
- Volunteers
- 218 people
- Sponsor
- Shanghai Mental Health Center
Tobacco Dependence
Effects of Yoga and Cardiovascular Exercise on Smoking Motivation
The overall purpose of this pilot study is to examine effects of Hatha yoga and cardiovascular exercise on craving, mood, cue reactivity, and smoking behavior.
- Trial name
- NCT01423578
- Testing
- Hatha Yoga (HY), Cardiovascular Exercise (CE), Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
HIV Infections, AIDS
HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
Background: The incidence of lung cancer is quite high among people with the human immunodeficiency (HIV) virus. Frequent smoking may explain that cancer increase, given that 50% to 70% of HIV-infected people are current smokers.
- Conditions
- HIV Infections, AIDS, Lung Cancer, Tobacco Addiction
- Trial name
- NCT00491335
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Smoking Cessation, Second Hand Tobacco Smoke
The "Quit-for-Kids" Project: to Increase Abstinence and Protect Children From Tobacco Smoke Exposure
This project aims to test the effectiveness of an integrated intervention of brief cessation advice (AWARD), Nicotine Replacement Therapy, and Instant Messaging support compared with waitlist control participants among adult…
- Trial name
- NCT06127589
- Testing
- Brief cessation advice (AWARD), Nicotine Replacement Therapy (NRT), Instant messaging Support (IM)
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Ostracism
Experiment Among Smokers in Which Two Variables Are Manipulated: Ostracism and Concealability
The goal of this experimental study is to learn about the effects of ostracism and concealment among adult smokers. The main aims are: 1. Determine the causal consequences of gendered stigmatization.
- Trial name
- NCT06462950
- Testing
- Do men and women differ in their reactions to the experimental conditions.
- Volunteers
- 340 people
- Sponsor
- Dickinson College
Smoking Cessation, Respiratory Disease
The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig) on Respiratory Symptoms
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Respiratory symptoms outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03632421)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alcoholism, Smoking
Behavioral/Drug Therapy for Alcohol-Nicotine Dependence (Naltrexone/Nicotine Patch)
This study will develop a behavioral and drug relapse prevention program for individuals who are dependent on both alcohol and tobacco.
- Trial name
- NCT00000447
- Testing
- naltrexone (Revia), nicotine replacement patch
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Electronic Cigarette Use
Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers
This study is being conducted to evaluate nicotine uptake and exposure, the abuse liability, and puffing topography associated with the use of an electronic nicotine delivery system ENDS with tobacco- and menthol-flavored…
- Trial name
- NCT04640285
- Testing
- RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, Usual Brand Cigarette
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Cheerain HK Limited
Smoking Cessation
Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study
The study aims to evaluate the feasibility of using Dorsolateral Prefrontal Cortex (DLPFC) Transcranial Direct Current Stimulation (tDCS) as a tool to decreasing distress and cigarette smoking.
- Trial name
- NCT05460676
- Testing
- Transcranial Direct Current Stimulation (tDCS), Mindfulness
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Smoking Cessation, Mouth Diseases
Tobacco Cessation Intervention Study for Oral Diseases
This study is to verify the efficacy of tobacco cessation in patients with oral diseases; periodontitis, dental implant and oral mucosal diseases by a multicenter prospective trial.
- Conditions
- Smoking Cessation, Mouth Diseases, Periodontal Diseases, Leukoplakia
- Trial name
- TISOD (NCT02737176)
- Testing
- Tobacco cessation intervention
- Where
- 2 sites in Japan
- Volunteers
- 812 people
- Sponsor
- Association for the Japanese Academy of Maxillofacial Implants
Vasovagal Syncope, Smoke Inhalation
Relation Between Vasovagal Tendency and Smoking Among University Students
Almost everyone is aware these days is aware about the risk of smoking. Still many people start this habit specially in early life and during college year.
- Trial name
- NCT02949804
- Testing
- Comparison between two groups
- Where
- Jordan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jordan Collaborating Cardiology Group
Smoking, Smoking Behaviors
Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction
The study will recruit an anticipated 256 adults who currently smoke cigarettes and report a willingness to try switching to alternative, non-combustible products.
- Conditions
- Smoking, Smoking Behaviors, Nicotine Dependence
- Trial name
- NCT06077240
- Testing
- E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors, E-cigarette with 2.4% Nicotine with Tobacco Flavor Only, E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Yale University
Nicotine Addiction
tDCS Effects on Resisting Smoking: Dose Ranging Study
Behaviors such as tobacco use, unhealthy diet, and sedentary behavior have far-reaching health implications. These modifiable behaviors account for a substantial proportion of deaths from cancer, cardiovascular disease and…
- Trial name
- RDR (NCT02624284)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity, Tobacco Smoking
Study of Bronchial Inflammation in Adolescent Smokers With and Without Obesity
The investigators want to assess differences in lung function and bronchial inflammation of young smokers and non-smokers with (BMI > 30) and without obesity (BMI < 25)(4 patient groups).
- Trial name
- NCT00942019
- Where
- Germany
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Smoking Cessation
Smoking Cessation for Hospital Employees With Low Education.
The aim of this trial is to develop a new tailored smoking cessation program for smokers with low education. Smokers are involved in design of the intervention.
- Trial name
- RESPEKT (NCT02701530)
- Testing
- Targeted smoking cessation
- Where
- Denmark
- Volunteers
- 7,003 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Tobacco Use, Periodontitis
Snuff Use, Smoking, Periodontal Health and Premature Death: 30-year Study
Snuff use and smoking associated with poor periodontal health, especially if used together.
- Trial name
- NCT03614871
- Testing
- Epidemiological study
- Volunteers
- 1,676 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
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