Clinical trials: Tobacco Smoking
AIDS/HIV
Smoking Cessation Intervention for Women Living With HIV
As people with HIV/AIDS live longer, the burden of non-AIDS-related health problems such as cardiovascular diseases and cancers on these people have consistently increased.
- Trial name
- SoCIWHIV (NCT02898597)
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Massachusetts, Boston
Smoking Cessation and Lung Cancer
Study of Psychopathological Characteristics of Patient Smoking in Thoracic Oncology
Persistent smoking after lung cancer has been the subject of medical, therapeutic and epidemiological publications for twenty years of research.
- Trial name
- NCT01955057
- Testing
- Research interviews, Tests (Fagerström, Q-MAT, H.A.D.S, SCL 90-R), Projective methods (Thematic apperception Test, Rorschach)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Healthy Volunteers
Effects of Smoking, Age and Body Size on Pharmacokinetics, Safety and Tolerability on Tasimelteon in Healthy Subjects
The purpose of this research study is to understand whether there is any difference in the amount of tasimelteon in the blood in smokers versus non-smokers.
- Trial name
- NCT01477619
- Testing
- Tasimelteon
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanda Pharmaceuticals
Healthy Subjects
Pharmacokinetics & Tolerability Study of MAP0004 in Smoking and Non-Smoking Adult Volunteers
Compare the pharmacokinetics of Dihydroergotamine Mesylate (DHE) delivered by oral inhalation (MAP0004) or Intravenous (IV) DHE in smokers versus non-smokers.
- Trial name
- NCT01199965
- Testing
- MAP0004, IV DHE
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Allergan
Nicotine Dependence, Smoking
Varenicline for Smoking Cessation in Heavy Drinking Smokers
The purpose of this study is to determine whether extended pretreatment with varenicline (Chantix) is more efficacious for smoking cessation than standard pretreatment, how well varenicline is tolerated in heavy drinking smokers…
- Conditions
- Nicotine Dependence, Smoking, Heavy Drinking
- Trial name
- NCT00860028
- Testing
- Extended Varenicline Pretreatment, Short-term Varenicline Pretreatment
- Volunteers
- 30 people
- Sponsor
- Yale University
Smoking
Oklahoma Weight Concerns Quitline: a Randomized Cessation Trial
The purpose of the "Weigh2Quit" study was to test in a randomized trial, a "weight concerns" intervention designed to reduce weight concerns that might impact cessation, increase physical activity and adherence to tobacco…
- Trial name
- OKRCT (NCT01162577)
- Testing
- Weight Concerns
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Consumer Wellness Solutions
Schizophrenia, Schizoaffective Disorder
Enhancing Motivation To Quit Smoking In Smokers With Serious Mental Illness
This project will assess the utility of a brief motivational intervention to engage smokers with schizophrenia in treatment for tobacco dependence treatment.
- Trial name
- NCT00500695
- Testing
- Motivational Interviewing, Psychoeducation
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Rutgers, The State University of New Jersey
Tobacco Dependence
Project 1, Study 1: Investigating the Impact of Nicotine Using Spectrum Cigarettes
Project 1, Study 1 will evaluate the relationship between nicotine yield of very low nicotine content cigarettes and cigarettes smoked per day, nicotine exposure, discomfort/dysfunction, other health-related behaviors…
- Trial name
- P1S1 (NCT01681875)
- Testing
- very low nicotine content cigarettes
- Where
- 9 sites in United States
- Volunteers
- 839 people
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use, Smoking Cessation
Can Cognitive Behavioural Therapy Help Incarcerated Men Quit Smoking? Efficacy and Predictors of Treatment Outcomes
The goal of this clinical trial is to evaluate whether a brief group-based psychological intervention using cognitive-behavioral therapy (CBT) helps people in prison quit smoking.
- Conditions
- Tobacco Use, Smoking Cessation, Cognitive Behavioral Therapy, Prisoners
- Trial name
- PriSanTabac (NCT06873009)
- Testing
- Cognitive-Behavioral Therapy (CBT) for Smoking Cessation, Health Education Session on Tobacco Use
- Where
- France
- Volunteers
- 202 people
- Sponsor
- Centre Hospitalier St Anne
Smoking, Smoking Behaviors
Abuse Liability of Two Modern Oral Nicotine Pouched Products
This is a single-site, open-label, randomized, 4-way cross-over study designed to evaluate elements of abuse liability (AL) including subjective effects and physiological measures (pharmacodynamics [PD]) and plasma nicotine…
- Conditions
- Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
- Trial name
- NCT07595055
- Testing
- Usual Brand (UB) filtered, menthol or non-menthol combustible cigarette, Modern Oral Pouch Wintergreen-A 9 mg Nicotine, Modern Oral Pouch Wintergreen-B 9 mg Nicotine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Smoking, Alcohol Drinking
Smoking and Alcohol Initiation
This study evaluates multi-attribute utility, a modification of subjective expected utility, as a descriptive model of the adolescent's decision to initiate smoking or alcohol use.
- Trial name
- NCT00271843
- Where
- United States
- Volunteers
- 2,600 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Pulmonary Disease, Chronic Obstructive
Effect of Spiriva® on Health-related Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients Who Stopped Smoking During Treatment.
Post marketing Surveillance to gain insights into the effects of therapy with Spiriva® (tiotropium bromide) on health-related quality of life in COPD patients who stopped smoking during treatment and to obtain safety data…
- Trial name
- NCT02172547
- Testing
- Spiriva
- Volunteers
- 10,821 people
- Sponsor
- Boehringer Ingelheim
Smoking, Alcoholism
Combination Nicotine Replacement for Alcoholic Smokers
The overall objective of the study is to develop recommendations for treatment programs to help alcoholic smokers to stop smoking.
- Trial name
- NCT00064844
- Testing
- Cognitive Behavior Therapy for alcohol and smoking cessation, Nicoderm CQ nicotine patch, Nicotine gum - Nicorette®
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Yale University
Cigarette Smoker
Validation of Biomarkers of Exposure and Host Response
This study will evaluate biomarkers measured in exhaled breath condensate (EBC) to assess clinical strategies of harm reduction.
- Trial name
- NCT00468234
- Testing
- nicotine polacrilex, nicotine transdermal system, nicotine inhaler
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Smoking
Building a Community-based Network to Promote Smoking Cessation
This study describes the development of a community-based network to promote smoking cessation among female smokers in Hong Kong.
- Trial name
- NCT02968199
- Testing
- A brief intervention
- Where
- China
- Volunteers
- 457 people
- Sponsor
- The University of Hong Kong
Smoking Status, Cigarette Consumption
Analysis of 'Tobacco and Alcohol Tax Law' and Its Impact on Cigarette Consumption
This project is the survey on smoking behavior in Taiwan. The survey information will be used to analyze the influence of the earmarked tax of cigarettes on (1)the consumption of cigarette,(2)the substitution between the…
- Trial name
- NCT00262158
- Volunteers
- 4,000 people
- Sponsor
- National Health Research Institutes, Taiwan
Therapeutic Equivalency
Fasting Bioequivalence Study of Pravastatin Sodium 80 mg Tablets Versus Pravachol® 80 mg Tablets In Normal Healthy Subjects
The objective of this study was to compare the rate and extent of absorption of pravastatin sodium from a test formulation of Pravastatin Sodium 80 mg Tablets versus the reference Pravachol® 80 mg Tablets under fasting…
- Trial name
- NCT00650221
- Testing
- Pravastatin
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Infertility
Impact of Male Smoking on the Couple's Infertility
About 15% of couples consult for difficulties achieving pregnancy. In about two-thirds of cases, a male component is identified, but is not always sufficient to explain infertility.
- Trial name
- TABAFERTIMASC (NCT02803658)
- Testing
- smoking behavior, Sperm collection
- Where
- 2 sites in France
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hospitalization, Smoking
Impact of Twice-daily Measurement of Expired CO During Hospitalization on Smoking
The main objective of this study is to show that the repeated (twice-daily) measurement of expired CO during hospitalization helps reduce smoking.
- Trial name
- CoCHU (NCT03729063)
- Testing
- Twice-daily expired carbon monoxide (CO) measurements, Minimal control
- Where
- France
- Volunteers
- 67 people
- Sponsor
- University Hospital, Montpellier
HIV, AIDS
Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care
To determine the efficacy of an algorithm designed to recommend smoking cessation-related pharmacotherapy options to the primary care providers of smokers living with HIV/AIDS.
- Conditions
- HIV, AIDS, Smoking Cessation
- Trial name
- NCT03670316
- Testing
- Algorithm Treatment, Quitline only
- Where
- United States
- Volunteers
- 371 people
- Sponsor
- University of Alabama at Birmingham
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