Clinical trials: Tobacco Smoking
Tobacco Use Cessation, Tobacco Use Disorder
Progesterone & Postpartum Relapse to Smoking
The primary goal of this project is to investigate the potential efficacy of exogenous progesterone (with supplemental relapse prevention counseling) on postpartum relapse in new mothers.
- Trial name
- NCT01798394
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
COPD
Adverse Health Effects of Mainstream and Secondhand Hookah Smoke in NYC Hookah Bars
The primary purpose of this study is to examine the health effects of mainstream and secondhand hookah (i.e. water pipe) smoke on pulmonary and cardiovascular functions as well as serum levels of inflammatory biomarkers.
- Trial name
- NCT02638194
- Testing
- Active smoking of Tobacco Hookah for 2 hours, Exposure to tobacco hookah second hand smoke, Visit a win bar
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Tobacco Use Disorder
Improving Smoking Cessation Outcomes in Heavy Drinkers - 1
To test the effectiveness of an smoking cessation treatment for smokers who also drink alcohol heavily.
- Trial name
- NCT00107575
- Testing
- Standard treatment plus brief alcohol intervention, Standard treatment (ST)
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Brown University
Cancer
Effect of an Acute Bout of Exercise on Smoking Topography
Smokers will complete questionnaires and smoking behaviour will be examined. After abstaining from smoking for approximately 18 hours, they will be randomized to a moderate intensity exercise group or passive sitting group.
- Trial name
- NCT01431365
- Testing
- Moderate Exercise Group, Passive Sitting Group
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Nicotine Dependence
Maintaining Nonsmoking
The research is based on a chronic disorder model of cigarette smoking which suggests that long-term treatment targeted to prevent relapse may be useful.
- Trial name
- NCT01162239
- Testing
- Varenicline, Initial Individual counseling, Check-ins with medical staff
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cannabis Use, THC
Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults
The goal of this interventional study is to determine the impact of high potency THC product use on cognitive function of young adults aged 21-25.
- Conditions
- Cannabis Use, THC, Marijuana Use, Cognitive Impairment
- Trial name
- THC-YA (NCT06077292)
- Testing
- 15% THC Potency Reduction, 35% THC Potency Reduction
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Cessation, Tobacco Use Disorder
Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid
Coal miners in Central Appalachia have among the highest rates of tobacco and nicotine product (TNP) use of any occupational group and face elevated rates of lung cancer and coal workers' pneumoconiosis ("black lung").
- Conditions
- Tobacco Use Cessation, Tobacco Use Disorder, Nicotine Dependence, Smokeless Tobacco Use
- Trial name
- NCT07694492
- Testing
- QuitAid (pharmacist-delivered MTM), Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Smoking
Web and Mobile Smoking Cessation
This study seeks to develop and then perform a controlled efficacy Randomized Controlled Trial assessing tobacco abstinence of a best-practices Web-based PC-delivered smoking cessation intervention (QuitOnline) compared to a…
- Trial name
- MobileQuit (NCT01952236)
- Testing
- Web+Mobile, Web Only
- Where
- United States
- Volunteers
- 1,266 people
- Sponsor
- Oregon Research Institute
Electronic Cigarette Use
Developing and Testing Health Warning Labels on the ENDS Device
In this project, after systematically developing electronic nicotine delivery systems (ENDS) pictorial health warning labels (HWLs), a proven clinical lab model will be used to examine and test their effect when these are placed…
- Trial name
- NCT04907136
- Testing
- Preferred ENDS, Preferred ENDS with HWL
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Florida International University
Periapical Periodontitis
Healing of Apical periodontitis-the Effect of Diabetes Mellitus and Tobacco Smoking
Apical periodontitis is an inflammatory process located around the apex of the root. It is mainly caused by a microbial infection of the pulp space.
- Trial name
- NCT04812171
- Testing
- non-surgical endodontic treatment
- Where
- Croatia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Romana Peršić Bukmir
Smoking Cessation, Tobacco Use Disorder
Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1
Currently one in five high school students smokes. Smoking can harm adolescents well before they reach adulthood by causing a number of immediate, sometimes irreversible, health risks and problems.
- Trial name
- NCT00158171
- Testing
- Nicotine Replacement Therapies, Nicotine patch, Folic Acid
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation, Harm Reduction
Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction
This open-label study will explore the impact of varenicline on the process of switching from combustible cigarettes (CC) to an e-cigarette.
- Trial name
- EVAR (NCT04210180)
- Testing
- Varenicline, e-cigarette
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Smoking Cessation
Mindfulness Training for Smoking Cessation
Participants will complete this study remotely, either at home or at their preferred location using an online platform. The investigators propose to test the effects of a mindfulness training [MT: Headspace] intervention compared…
- Trial name
- NCT05440903
- Testing
- Headspace, TEDTalk
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Nicotine Dependence
Effects of Varenicline on Brain Activity During Nicotine Abstinence
This project aims to define mechanisms through which varenicline might be an effective smoking cessation medication.
- Trial name
- NCT00602927
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Chronic Obstructive Airway Disease
Pulmonary Disease in a Psychiatric Inpatient Population
Purpose: Patients with mental health disorders have a reduced life expectancy, compared to the general population. The shorter life expectancy is caused by natural and unnatural death.
- Trial name
- NCT01823627
- Testing
- Spirometry with reversibility test
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Psykiatrien Syd
Nicotine Dependence
Evaluation of Learning-Theory-Based Smoking Cessation Strategies
This clinical trial tested whether a new treatment designed to help smokers prepare to quit smoking by practicing quitting several times helped more smokers quit and stay quit than standard treatment with nicotine patch and…
- Trial name
- NCT01368653
- Testing
- Standard treatment, Standard treatment+practice quitting, Very low nicotine cigarettes
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Smoking Cessation
Young Adult Smoker's Treatment Demand
The purpose of this study is to determine whether tailored online advertisements will drive young adult smoker's (18 to 26 years old), who are motivated to quit, to use Internet-based cessation treatment.
- Trial name
- NCT01569529
- Testing
- Online advertisement
- Where
- United States
- Volunteers
- 3,070 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Smoking, Betel Nut
Biobehavioral and Cultural Determinants of Betel Quid Chewing, Dependence, and Withdrawal in Taiwan
Cancer of the oral cavity is one of the fastest growing cancers among men in Taiwan. Previous research has established a strong link between betel quid chewing, a common practice among Taiwanese men, and oral cancer.
- Trial name
- BCDBQCDWT (NCT02167295)
- Where
- Taiwan
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Human Immunodeficiency Virus, Smoking Cessation
Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV
Smokers living with HIV represent a major health disparity population in the United States and the world more generally. Major contributing factors to the maintenance and relapse of smoking among smokers living with HIV include…
- Conditions
- Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette, Smoking
- Trial name
- NCT03904186
- Testing
- QUIT, Time-Matched Control (TM)
- Where
- 3 sites in United States
- Volunteers
- 131 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation
Pennsylvania Adolescent Smoking Study (PASStudy)
The Pennsylvania Adolescent Smoking Study (PASStudy) will evaluate the effectiveness of Motivational Interviewing (MI) compared to Structured Brief Advice (SBA) to reduce cigarette smoking among adolescents who smoke.
- Trial name
- NCT00381329
- Testing
- Motivational Interviewing (MI), Structured Brief Advice (SBA)
- Where
- 3 sites in United States
- Volunteers
- 330 people
- Sponsor
- Pennsylvania Department of Health
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