Clinical trials: Tobacco Smoking
Smoking Cessation
Trial of Cytisine in Adult Smokers
This placebo-controlled Phase 2b trial is being conducted at sites within the United States (US) to evaluate the effectiveness cytisine dosage (1.5 mg, 3.0 mg) and administration schedule (commercial titration versus simplified 3…
- Trial name
- NCT03709823
- Testing
- Cytisine, Behavioral support
- Where
- 8 sites in United States
- Volunteers
- 254 people
- Sponsor
- Achieve Life Sciences
Smoking, Smoking, Cigarette
The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers.
- Conditions
- Smoking, Smoking, Cigarette, Smoking, Tobacco, Betel Chewer's Mucosa
- Trial name
- NCT06535867
- Testing
- mHealth
- Where
- United States
- Volunteers
- 5,122 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
HIV, Tobacco Use
Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, Kenya
People with HIV (PWH) smoke tobacco cigarettes and drink alcohol at higher rates than the general population, both in the US and internationally, including low- and middle-income countries.
- Conditions
- HIV, Tobacco Use, Alcohol Use Disorder
- Trial name
- NCT06790342
- Testing
- Cystine, Positively Smoke Free, Standard of Care
- Where
- 2 sites in Kenya
- Volunteers
- 300 people
- Sponsor
- University of Chicago
Smoking, Tobacco, Second Hand Tobacco Smoke
Optimizing Smoke-free Residential Housing Policies
This project will be conducted to investigate activities on housing-related health and safety issues. The focus of this project is the development of evidence-based approaches to implement smoke-free policies to reduce harms…
- Conditions
- Smoking, Tobacco, Second Hand Tobacco Smoke, Smoking Cessation
- Trial name
- NCT04791722
- Testing
- Adaptive Intervention
- Where
- United States
- Volunteers
- 386 people
- Sponsor
- Harvard School of Public Health (HSPH)
Nicotine Dependence, Nicotine Dependence, Cigarettes
Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers
A Ten Sequence, Open Label, Randomized Crossover Study Comparing Nicotine Pharmacokinetics of JUUL 1.7% and JUUL 5% Nicotine Salt Based ENDS Products, in Healthy Adult Smokers.
- Conditions
- Nicotine Dependence, Nicotine Dependence, Cigarettes, Tobacco Use, Tobacco Smoking
- Trial name
- NCT03593239
- Testing
- Tobacco flavored JUUL 1.7% ENDS, Tobacco flavored JUUL 5% ENDS, Mint flavored JUUL 1.7% ENDS
- Where
- New Zealand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital
Smoking Cessation
Smoking Cessation Outcomes and Effective Factors
The study is a cross-sectional-descriptive study. Cases who met the inclusion criteria, agreed to participate in the study voluntarily, were active smokers, passive smokers and non-smokers will be included.
- Trial name
- NCT05695742
- Testing
- Active Smoking, Passive smoker, Non-smoker
- Where
- Turkey (Türkiye)
- Volunteers
- 893 people
- Sponsor
- Saglik Bilimleri Universitesi
Risk Behavior
Effectiveness of Counseling Interventions to Modify Risk Behaviors in Patients at the Hospital San Ignacio.
Randomized clinical trial that aims to determine the effectiveness of a counseling intervention to modify the stage of behavioral change in risk behaviors (smoking and risky alcohol consumption) in patients candidates for…
- Trial name
- EFICO (NCT03521622)
- Testing
- brief counseling
- Where
- Colombia
- Volunteers
- 440 people
- Sponsor
- Hospital Universitario San Ignacio
Smoking
European Exposure Study
The current study was designed to determine the exposure of adult smokers and non-smokers to cigarette smoke constituents through evaluation of selected biomarkers of exposure.
- Trial name
- NCT01237912
- Where
- United Kingdom
- Volunteers
- 1,667 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking Cessation, Health Behavior
A Health Recommeder System to Tailor Message Preferences in a Smoking Cessation Programme
Patients attending the smoking cessation programme at the Virgen del Rocío University Hospital under the SoLoMo clinical trial of the SmokeFreeBrain project and provided with the SoLoMo mobile app will be observed for one year.
- Conditions
- Smoking Cessation, Health Behavior, Smoking, Tobacco, Smoking
- Trial name
- NCT03206619
- Testing
- Social, Local and Mobile
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Seville
Tobacco Use Disorder
Fresh Lime Alone for Smoking Cessation
The purpose of this study is to determine whether fresh lime alone is effective for smoking cessation.
- Trial name
- LIM (NCT01333202)
- Testing
- Fresh lime
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Thai Health Professional Alliance Against Tobacco
Smoking, Nicotine Dependence
Nicotine TMS EFT Smoking Pilot Study
Prior and recent evidence suggests a role of medial prefrontal cortex (MPFC) in cigarette smoking. Episodic Future Thinking (EFT) has also been shown to be associated with increased delayed discounting and reduced cigarette self…
- Conditions
- Smoking, Nicotine Dependence, Addiction, Smoking, Cigarette
- Trial name
- NCT03579953
- Testing
- Real cTBS
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Medical University of South Carolina
Tobacco Smoking
Methods Project 4: Clinical Trial - Amended
Cigarette smokers will be randomized to E-cigarette, Nicotine Gum or Lozenge, or Control Group. Participants will enter a 1 week sampling phase.
- Trial name
- COMET (NCT03111537)
- Testing
- Cigarettes, E-Cigarette, Nicotine Gum or Lozenge
- Where
- 3 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use Disorder
Low Nicotine Content Cigarettes in Vulnerable Populations: Opioid Use Disorder
Prevalence of smoking among individuals with opioid use disorder (OUD) is six-fold that of the general US adult population. The mortality rate of opioid-dependent smokers is four times that of opioid-dependent nonsmokers, and…
- Trial name
- NCT04092101
- Testing
- Cigarettes with varying nicotine content, E-Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Orthopaedic Decision Making
Surgeon-Patient Communication: A Randomized Controlled Trial Evaluating the Impact of an Orthopaedic Related Smoking Cessation Discussion After Fracture Surgery
In this study, the investigators are interested in evaluating the impact of an orthopaedic related smoking cessation discussion after fracture surgery.
- Trial name
- NCT02440529
- Testing
- Intervention, Verbal Group
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Missouri, Kansas City
Smoking, Excessive Drinking
WHO-HPH Recognition Project on Fast-Track Implementation of Clinical Health Promotion
The project's background is the notion that patient centred clinical health promotion has been shown to significantly improve both outcomes and patient safety.
- Conditions
- Smoking, Excessive Drinking, Lack of Physical Activity, Malnutrition
- Trial name
- RP (NCT01563575)
- Testing
- fast-track implementation process
- Where
- 11 sites in Canada, Croatia and 9 more
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Cancer
Proactive Care Coordination for Cancer Survivors Who Smoke
This is a population-based randomized controlled trial of 600 patients with a diagnosis of cancer in the past 2 years and registry indicating smoking at the time of diagnosis, that will inform critical questions regarding the…
- Trial name
- NCT02723656
- Testing
- Online Referral NYS Quitline, Tobacco cessation counseling and coordination of cessation medications
- Where
- United States
- Volunteers
- 581 people
- Sponsor
- NYU Langone Health
Tobacco Smoking, Healthy Participants
Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model
The purpose of this pilot study is to evaluate allergen-induced nasal airway inflammation following nasal application of felis domesticus, or cat, extract in e-cigarette users, cigarette smokers, and non-smokers.
- Conditions
- Tobacco Smoking, Healthy Participants, E-cigarette Smokers
- Trial name
- Kitty Nose (NCT03031145)
- Testing
- Felis Domesticus
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Smoking
Nicotine Pharmacokinetic Profile of the CHTP 1.1 M
The primary objective of this clinical study is to evaluate the pharmacokinetic (PK) profile of nicotine (rate and amount of nicotine absorbed) after single use of the Carbon Heated Tobacco Product 1.1 Menthol (CHTP 1.1 M), a…
- Trial name
- NCT02466412
- Testing
- CHTP 1.1 M, mCC
- Where
- Japan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Healthy Participant
Different Modes of Universal Adhesive in Smokers and Non-Smokers
The aim of the study was to evaluate the influence of smoking on the clinical performance of a universal adhesive used with different application modes in non-carious cervical lesions.
- Trial name
- NCT04807465
- Testing
- G-Premio Bond in etch&rinse mode, G-Premio Bond in selective-etch mode, G-Premio Bond in self-etch mode
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
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