Clinical trials: Tobacco Smoking
Tobacco Dependence
Bupropion Alone or Combined With Nicotine Gum
Focus of this study was to determine if bupropion was more effective for smoking cessation when used alone or combined with nicotine gum.
- Trial name
- NCT01621022
- Testing
- bupropion + nicotine gum
- Where
- United States
- Volunteers
- 608 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cigarette Smoker, Current Every Day Smoker
Mobile Smoking Cessation Intervention in Enhancing Cancer Outreach in Low-Income Adult Smokers
This trial studies how well a mobile smoking cessation intervention works in enhancing cancer outreach in low-income adult smokers.
- Trial name
- NCT00948129
- Testing
- Laboratory Biomarker Analysis, Smoking Cessation Intervention, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Arthritis, Rheumatoid, Arthritis, Psoriatic
Characterization of Immunogenicity of TNF Inhibitors in Arthritis Patients With Poorer Treatment Response.
The aim of the study is to explore whether the influence of gender, tobacco smoking and obesity on treatment response in tumor necrosis factor inhibitors (TNFIs) can be explained by high degree of inflammation, human leucocyte…
- Conditions
- Arthritis, Rheumatoid, Arthritis, Psoriatic, Spondylitis, Ankylosing
- Trial name
- NCT04731831
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Aalborg University Hospital
Cigarette Smoking, Post Traumatic Stress Disorder
Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster
The purpose of this study was to test the efficacy of a CBT-based smoking cessation treatment enhanced with transdiagnostic skills for the management of anxiety and fear-based avoidance behaviors (CBT-A) relative to a standard…
- Conditions
- Cigarette Smoking, Post Traumatic Stress Disorder, Signs and Symptoms, Respiratory
- Trial name
- NCT02538601
- Testing
- CBT-A, CBT-S
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stony Brook University
Vaping, Adolescent Behavior
Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender Minority Teens
The investigators long-term goal is to reduce tobacco use and tobacco-related health disparities among SGM populations. The objective of Project SMART (Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender…
- Conditions
- Vaping, Adolescent Behavior, Communication Research
- Trial name
- SMART (NCT06308081)
- Testing
- Tailored
- Where
- United States
- Volunteers
- 1,155 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Smoking Cessation, Motivation
Smoking Cessation in Cancer Treatment
The intervention to be studied is a smoking cessation program offered to newly diagnosed cancer patients at their first consultation for treatment at an oncological hospital department.
- Trial name
- NCT03328962
- Testing
- Structured smoking cessation counselling based on motivational interviewing (MI) and adapted for the cancer setting eventually combined with provision of smoking cessation medication
- Where
- 6 sites in Norway
- Volunteers
- 1,200 people
- Sponsor
- Norwegian Institute of Public Health
E Cigarette Use
Impact of Aversive Warnings on E-Cigarette Cessation
This project aims to evaluate the effectiveness of aversive visual health warnings on e-cigarette cessation among young adults through a randomized controlled trial, as e-cigarette use among this population has been steadily…
- Trial name
- NCT05892445
- Testing
- Graphic Warning Labels
- Volunteers
- 1,000 people
- Sponsor
- University of California, San Diego
Nicotine Dependence, Nicotine Vaping
Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
In a crossover study, experienced electronic cigarette users will vape 3 different forms of nicotine: natural (derived from tobacco), synthetic, or a 50:50 mixture of both natural and synthetic.
- Trial name
- NCT05962229
- Testing
- (S)-Nicotine, (R)- nicotine, Racemic nicotine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cigarette, Smoking Behaviors
Vape Use Among Younger & Older Smokers
The study aims to recruit 100 current cigarette smokers (50 young adults ages 21-34; 50 older adults ages 35-65) who have tried vaping or are currently vaping (dual users).
- Conditions
- Smoking Cigarette, Smoking Behaviors, Vaping, Vaping Behaviors
- Trial name
- ENDS (NCT07214168)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Tobacco Smoking Behavior
MassCONECT (Massachusetts Community Networks to Eliminate Cancer Disparities Through Education) 4 Kids: Promoting Smoke-free Homes
This study evaluates the effectiveness of a motivational interviewing intervention with families with young children ages 0-5 where smoking is happening in the home to adopt a smoke-free home plan and reduce child's second-hand…
- Trial name
- NCT01537874
- Testing
- Motivational Interview, Usual best practices
- Where
- 3 sites in United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Smoking Cessation, Alcohol Consumption
Smoking Cessation in Alcoholics
Most alcohol-dependent individuals are heavy smokers. The aim of this study is to evaluate whether a specific smoking cessation program (based on cognitive-behavioral therapy) for inpatient alcohol-dependent smokers is more…
- Trial name
- NCT00963482
- Testing
- Cognitive-behavioural smoking cessation program, Autogenic training
- Where
- Switzerland
- Volunteers
- 103 people
- Sponsor
- University Hospital, Basel, Switzerland
Smoking Cessation
Smoking Cessation in NYC
The investigators tested the feasibility of a culturally and linguistically sensitive smoking cessation program with combined counseling and pharmacological components for Chinese smokers in New York City; identified factors and…
- Trial name
- NCT04489524
- Testing
- individualized counselor-led MI sessions, general health education session, NRT
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Temple University
Tobacco Use Cessation
Evaluating the Feasibility and Efficacy of a Real-time Smoking Intervention Using Wearable Technology
This study will use wearable technology to test the feasibility and efficacy of delivering a novel real-time smoking intervention to improve standard tobacco treatment.
- Trial name
- NCT04172623
- Testing
- Real-Time Smoking Intervention, Standard Treatment
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Yale University
Smoking Cessation
New Strategies to Enhance Smoking Cessation
The study goal is to get feedback on ways researchers can communicate complex research findings on smoking cessation to better inform patients' decisions to use medication and/or quit smoking.
- Trial name
- NCT06751927
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Smoking, Tobacco
A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers
The overall purpose of this study will be to assess primary combustible cigarette users' abstinence from smoking their usual brand of combustible cigarettes at the end of the study, when provided with an electronic nicotine…
- Trial name
- NCT07172438
- Testing
- P2611222, P2615022, P2615122
- Where
- 27 sites in United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Pregnant Women's Tabacco Exposure
Pregnant Women's Knowledge of the Active and Passive Smoking Effects on Pregnancy and the Fetus
There are two remaining areas where the standards for tobacco use during pregnancy have changed little: one area is the high level of consumption by pregnant women and the other is the limited care given to pregnant women.
- Trial name
- tabac-GO (NCT06117943)
- Testing
- data collection
- Where
- 2 sites in France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Smoking Cessation
Smoking Cessation and Relapse Prevention in Women Postpartum
Background: Pregnancy was found to be a significant triggering factor for smoking cessation and the reduction of nicotine consumption, but 50 - 70 % of mothers who stopped smoking during pregnancy resume tobacco smoking after…
- Trial name
- EARLINT-EP3 (NCT00475046)
- Testing
- Motivational Interviewing
- Volunteers
- 2,790 people
- Sponsor
- University Medicine Greifswald
Lower Back Pain
Assessment of Chiropractic Treatment for Low Back Pain and Smoking Cessation in Military Active Duty Personnel.
The purpose of this study is to evaluate the effectiveness of chiropractic manipulative therapy for pain management and improved function in active duty service members with low back pain that do not require surgery.
- Trial name
- NCT01692275
- Testing
- Medical Care + Chiropractic Care, Conventional Medical Care Only
- Where
- 3 sites in United States
- Volunteers
- 750 people
- Sponsor
- RAND
E-cigarette Use, Microcirculation
The Acute Effects of E-cigarette Inhalation on Vascular Function, Microcirculation and Thrombosis
This is a human randomized controlled cross-over study where the effects of e-cigarette inhalation (with or without nicotine) on vascular function, microcirculation and thrombosis is assessed.
- Conditions
- E-cigarette Use, Microcirculation, Thrombosis, Vascular Function
- Trial name
- NCT04175457
- Testing
- e-cigarette
- Where
- Sweden
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Smoking Cessation
A Pharmacokinetic and Pharmacodynamic Evaluation of Cytisine in Healthy Smokers
The primary objectives of this study are: To evaluate the pharmacokinetic (PK) parameters during repeat dosing of 1.5 mg or 3.0 mg cytisine when administered as the commercial 25-day schedule.
- Trial name
- NCT03303911
- Testing
- Cytisine
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Achieve Life Sciences
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