Clinical trials: Tobacco Smoking Behavior
Smoking Cessation, Tobacco Use Disorder
Effectiveness of Reducing Smoking in Facilitating Smoking Cessation in Adolescents - 2
Currently one in five high school students smoke. Smoking can harm adolescents well before they reach adulthood by causing a number of immediate, sometimes irreversible, health risks and problems.
- Trial name
- NCT00158158
- Testing
- Usual Care, Smoking Reduction
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation
Determinants of Smoking Cessation Among Latinos
The goal of this study is to learn how neighborhood and individual factors affect the ability to stop smoking among Spanish-speaking Mexican American (MA) smokers who want to quit smoking.
- Trial name
- NCT01008748
- Testing
- Nicotine Replacement Therapy (NRT), Questionnaire, Counseling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
COPD, Emphysema
Efficacy of Losartan in Preventing Progression of COPD
Evidence in animals shows that losartan can prevent or reverse inflammation and lung damage due to smoking. The goal of this study is to determine whether this drug which is also used to treat hypertension can stabilize or…
- Conditions
- COPD, Emphysema, Chronic Bronchitis, Smoking
- Trial name
- NCT00720226
- Testing
- Losartan
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Johns Hopkins University
Smoking, Nicotine Addiction
The END Perioperative Smoking Pilot Study
The purpose of this pilot randomized trial is to determine the feasibility of e-cigarettes and telephone counselling (compared to transdermal nicotine replacement and telephone counselling) as a harm-reduction tool that may lead…
- Conditions
- Smoking, Nicotine Addiction, Surgery
- Trial name
- NCT02482233
- Testing
- ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Smoking
Impact of Graphic Cigarette Warnings
The purpose of this randomized controlled trial is to determine whether graphic health warnings on cigarette packs are more effective than the existing Surgeon General's warning on cigarette packs at encouraging quit attempts.
- Trial name
- NCT02247908
- Testing
- Surgeon General's Warning, Graphic Warning
- Where
- 2 sites in United States
- Volunteers
- 2,149 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cigarette Smoking, Tobacco Use
Gabapentin for Smoking Cessation
Gabapentin is an anti-epileptic agent that has shown preliminary evidence of efficacy for improving symptoms of cocaine and alcohol withdrawal in pilot studies.
- Trial name
- NCT00578552
- Testing
- Gabapentin - 1800 mg/day, Gabapentin - 2700 mg/day
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Periodontal Diseases, Smoking
The Effect of Scaling and Root Planing on Oral Inflammatory Biomarkers Among E-cig Users and Non-smokers
Background/Aim: There are no studies that have compared the gingival crevicular fluid (GCF) levels of IL-1β in non-smokers (NS) and electronic nicotine delivery system (ENDS)-users before and after scaling and root planing (SRP)…
- Trial name
- ENDS-SRP (NCT05745324)
- Testing
- Scaling and root planing
- Where
- Kuwait
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Smoking Cessation, Diabetes
Efficacy And Safety Of Smoking Cessation With Varenicline Tartrate In Diabetic Smokers: (DIASMOKE)
Objectives This protocol is intended to provide information regarding the efficacy and safety of the nicotine partial agonist varenicline tartrate, at a dose of 1 mg twice daily, for smoking cessation in diabetic subjects who…
- Trial name
- DIASMOKE (NCT01387425)
- Testing
- varenicline
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- University of Catania
Smoking, Smoking Cessation
Smoking Cessation on the Human Airway: Mucus Secretion, Inflammatory and Proteomic Profile in Nose and miRNAs in Blood
Smoking cessation improves health conditions with reduction of the risk factors for cardiovascular and respiratory disease, as functional capacity and quality of life.
- Trial name
- NCT02136550
- Testing
- Smoking cessation
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cigarette Smoking
Tailored Web and Peer Email Cessation Counseling for College Smokers
The RealU2 is a randomized controlled trial to determine the efficacy of an online health and wellness program for young adults with the addition of individualized peer health coaching.
- Trial name
- RealU (NCT01604525)
- Testing
- Tailored Web, Peer Coaching, Untailored Web
- Volunteers
- 1,699 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Periodontitis
The Influence of Smoking in Periodontitis Patients, Before and After Nonsurgical Treatment
Objective: The aim of this study was to evaluate and compare the oral neutrophil numbers (ONN) in saliva, the level of matrix metalloproteinase-8 (MMP-8) in gingival crevicular fluid (GCF) and the periodontal parameters in…
- Trial name
- NCT04974502
- Testing
- Nonsurgical periodontal treatment
- Volunteers
- 40 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Smoking
Internet Stop Smoking Study - Phase VI
The purpose of this study is to determine the percentage of English- and Spanish-speaking smokers worldwide who can stop smoking using an Internet stop smoking site. Latinos and non-Latinos are welcome to participate.
- Trial name
- TC4 (NCT00721786)
- Testing
- UCSF/SFGH Internet Stop Smoking Study site
- Where
- United States
- Volunteers
- 18,154 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Effects of E-smoke on Levels of Endothelial Progenitor Cells and Microparticles in Healthy Volunteers
We plan to investigate the acute effects of inhaling e-cigarette vapor on cell function measured by microvesicles and endothelial progenitor cells.
- Trial name
- ESMOKE (NCT02532894)
- Testing
- Electronic cigarette
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Smoking Cessation
The Effect of the Education Program Based on the PRECEDE-PROCEED Model on the Smoking Behaviors of Nursing Students
The causes of death due to smoking are responsible for 11.5% of the total deaths in the world. Smoking causes lung cancer, chronic obstructive pulmonary disease (COPD), ischemic heart disease and cerebrovascular diseases.
- Trial name
- NCT05314894
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Tobacco Use Disorder
Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation
The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers.
- Trial name
- NCT05726045
- Testing
- Standard smoking cessation program (SCP), Cognitive remediation treatment (CRT), High-intensity interval training (HIIT evening)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Tobacco Cessation
Support Person Intervention to Promote a Smoking Helpline Among Under Resourced Smokers
This pilot study is being done to adapt an effective 1 session phone coaching intervention for nonsmoking support persons to a low income population.
- Trial name
- NCT03096145
- Testing
- Telephone counseling 1 session, Mobile texting, Health incentive
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Use
Pilot Randomised Controlled Trial of ToQuit Intervention in India
Tobacco use is associated with high mortality, and a range of morbidities including cancer, and lung and cardiovascular diseases.
- Trial name
- ToQuit (NCT04782453)
- Testing
- ToQuit, a technology delivered tobacco cessation intervention, Tobacco quitting helplines
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sangath
Smoking
Exploratory THS 2.1 Nicotine Pharmacokinetics and Safety Study
The main goal of this exploratory study is to evaluate the pharmacokinetic profile of nicotine for the candidate modified risk tobacco product THS 2.1 and for conventional cigarettes (CC).
- Trial name
- NCT01780688
- Testing
- Conventional cigarettes (CC), THS 2.1
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking Cessation
Improving Adherence to Web-Based Cessation Programs: A Social Network Approach
This study will compare the efficacy of an interactive, evidence-based smoking cessation website (WEB) alone and in conjunction with 1) a theory-driven, empirically-informed social network (SN) protocol designed to integrate…
- Trial name
- NCT01544153
- Testing
- WEB, Social Network, Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 5,292 people
- Sponsor
- Truth Initiative
Tobacco Smoking
Smoking Prevalence at a University Hospital
Tobacco is the leading risk factor for avoidable mortality in France and around the world. It is also the second cause of life with disability in the world and the leading preventable risk factor for cancer in France and…
- Trial name
- TABAC-HCL (NCT03268980)
- Testing
- Questionnaire Hospital Staff group, Questionnaire students and patients group
- Where
- France
- Volunteers
- 11,276 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon