Clinical trials: Tobacco Use Cessation
Tobacco Dependence
Prolonged Smoking Cessation Using Prescription Step Care
Smoking is the number one preventable cause of morbidity and mortality in this nation. Unfortunately, more than 50% of those who quit following a smoking cessation intervention typically relapse within two weeks, with…
- Trial name
- NCT00170079
- Testing
- Smoking Cessation Intervention
- Where
- 2 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Smoking, Tobacco Use Cessation
Group Therapy for Nicotine Dependence: Mindfulness and Smoking
The goal of this behavioral research study is to create and study a Mindfulness-Based Addiction Treatment (MBAT) for nicotine dependence.
- Trial name
- NCT00297479
- Testing
- MBAT Group Therapy, Nicotine, Group Therapy
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Tobacco Use Disorder, Mental Disorders
Effectiveness of Smoking Cessation Education
Smoking is an important psychosocial problem that concerns society. It is reported that 1.3 billion people use tobacco products in the world and approximately 6 million people lose their lives due to smoking every year.
- Conditions
- Tobacco Use Disorder, Mental Disorders, Smoking Cessation
- Trial name
- NCT06930547
- Testing
- Experimental
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Technical University
Tobacco Use Disorder
Innovative Interventions for Smoking Cessation
The purpose of this study is to evaluate the effect of a combination of the 21 mg nicotine patch and very low nicotine content (VLNC) cigarettes compared to 21 mg nicotine patch only and very low nicotine content cigarette only…
- Trial name
- NCT01050569
- Testing
- Nicotine Patch, VLNC Cigarette, VLNC Cigarette Plus Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence
Study of Varenicline (Champix) for Smoking Cessation/Reduction in Patients With Bipolar Disorder
Bipolar Disorder is a chronic relapsing mental disorder characterized by periods of elevated, expansive and irritable mood, often alternating with periods of significant clinical depression.
- Trial name
- NCT01093937
- Testing
- varenicline
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Cigarette Smoking
Mood Management Phone Counseling in Smoking Cessation
Information obtained from this study will help us to have a better idea of how phone counseling may facilitate the process of quitting smoking for individuals with a history of recurrent depression.
- Trial name
- NCT00500877
- Testing
- Mood Management Phone Counseling for Smoking Cessation
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Butler Hospital
Nicotine Dependence
Electronic Nicotine Delivery Systems as a Smoking Cessation Treatment
The purpose of this research study is to determine whether combining electronic nicotine delivery systems (ENDS) with nicotine patch treatment will augment abstinence rates compared to either treatment alone.
- Trial name
- ENDS-P50 (NCT02487953)
- Testing
- Nicotine patch, ENDS
- Where
- United States
- Sponsor
- Duke University
Cigarette Smoking
Tailored Tobacco Quitline for Rural Veterans
The proposed work is designed to help increase access to tobacco cessation services among rural veterans and to develop more effective treatment services that better address comorbid issues commonly experienced by rural smokers.
- Trial name
- NCT01592695
- Testing
- Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Smoking Cessation, Smoking, Tobacco
Pivot Breath Sensor Performance Study
A clinical study enrolling 70 subjects to: evaluate the user performance of the Pivot Breath Sensor compare measurements from the Pivot Breath Sensor to a similar device assess user documentation comprehension obtain feedback on…
- Trial name
- NCT03870022
- Testing
- Pivot Breath Sensor System, Similar Carbon Monoxide breath sensor system
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Jennifer Marler, MD
Tobacco Use, Smoking Cessation
Overcoming Nicotine Dependence to Enable Quitting
Tobacco use disorder is a chronic, relapsing health condition that necessitates a chronic care approach. However, traditional smoking cessation treatment programs allocate nearly all their resources only to those smokers who are…
- Conditions
- Tobacco Use, Smoking Cessation, Smoking Behaviors, Nicotine Dependence
- Trial name
- ON-DEQ (NCT05513872)
- Testing
- Nicotine Replacement Therapy (NRT) Sampling, Practice Quitting (PQ) Counseling, Motivational Interviewing (MI) Counseling
- Where
- United States
- Volunteers
- 780 people
- Sponsor
- Rush University Medical Center
Smoking, Smoking Cessation
Couples Dynamics and Smoking Cessation
This study is about investigating smoking and attempts to quit smoking in couples. Participation will help determine better treatment efforts for couples who want to quit smoking.
- Conditions
- Smoking, Smoking Cessation, Cessation, Smoking, Smoking Behaviors
- Trial name
- SCOR (NCT03885336)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of Southern California
Nicotine Dependence
Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study
One of the most promising lines of investigation for the therapeutic use of hallucinogens in the 1960s and 1970s was in the treatment of drug dependence.
- Trial name
- NCT01943994
- Testing
- Psilocybin-assisted treatment, Nicotine Replacement Therapy (NRT)
- Where
- 2 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tobacco Use Disorder, Nicotine Dependence
Young Adult Tobacco/Nicotine and Cannabis Co-use
The goal of this project is to better understand the relationship between tobacco/nicotine and cannabis using behavioral economics during a tobacco/nicotine quit attempt.
- Trial name
- YouthCAT (NCT06239350)
- Testing
- Counseling, Contingency management, Text-based support
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cigarette Smoking, Current Smoker
Quit4Health Intervention in Supporting Smoking Cessation and Preventing Smoking Initiation in Young Adults
This trial studies how well Quit4Health intervention works in supporting smoking cessation and preventing smoking initiation in young adults.
- Trial name
- NCT04009590
- Testing
- Educational Intervention, Questionnaire Administration, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking
Reaching and Treating Lesbian, Gay, Bisexual, and Transgender (LGBT) Cigarette Smokers
Smoking rates are significantly higher among lesbian, gay, bisexual, and transgender (LGBT) populations compared to the general population.
- Trial name
- NCT00634218
- Testing
- Mail-based Self-help plus Internet-based Smoking Treatment, Self-Help Manual plus Telephone counseling, Self-Help Manual
- Where
- United States
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Implementation Science, Engagement, Patient
Parents Helping Parents for Youth Vaping Cessation
The goal of this randomized controlled study is to test if this new intervention works to help adolescents quit vaping. A key feature of the program is the use of peer support for parents, delivered by trained parent coaches.
- Conditions
- Implementation Science, Engagement, Patient, E Cigarette Use, Peer Support
- Trial name
- PhP-VX (NCT07207850)
- Testing
- Parents Helping Parents program
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Nebraska
Schizophrenia, Smoking Cessation
Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia
Purpose of the study: Evaluate the effect of deep repetitive transcranial magnetic stimulation (deep rTMS; hereafter abbreviated as "dTMS") on synaptic density measured with positron emission tomography (PET) and the radiotracer…
- Conditions
- Schizophrenia, Smoking Cessation, Tobacco Use
- Trial name
- NCT05724810
- Testing
- Active deep transcranial magnetic stimulation (dTMS)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stony Brook University
HIV, AIDS
Smoking Cessation for People Living With HIV/AIDS
In this proposed study with People Living with HIV/AIDS (PLWHA), we will use a stepped care model called a Sequential Multiple Assignment Randomized Trial (SMART) to examine the efficacy of low- and high-intensity smoking…
- Conditions
- HIV, AIDS, Nicotine Dependence
- Trial name
- NCT01965405
- Testing
- Bupropion, Brief Counseling, High-magnitude prize contingency management
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Wayne State University
Tobacco Use Cessation
Smoking Cessation Support for Patients With Rheumatologic Diseases Via WhatsApp
Smoking cessation support for patients with rheumatologist diseases is an underestimated issue. In the previous prospective cohort study the investigators determined that with the brief cessation interventions 63.5% of smokers…
- Trial name
- NCT06219551
- Testing
- Mobile messages via What's App
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Cigarette Smoking, Nicotine Addiction
STOP Study: Effectiveness of Zyban in a Clinical Population
Despite the significant health, social and economic costs of cigarette smoking, 17% of Ontarians still currently smoke. Use of smoking cessation pharmacotherapy such as Zyban (bupropion HCl) has been shown to double quit rates…
- Conditions
- Cigarette Smoking, Nicotine Addiction, Smoking Cessation
- Trial name
- NCT01015170
- Testing
- bupropion HCl
- Where
- 24 sites in Canada
- Volunteers
- 454 people
- Sponsor
- Centre for Addiction and Mental Health