Clinical trials: Tobacco Use Cessation
Smoking Cessation
Empowering LGBTQ+ Tobacco Cessation Pilot
Sexual and/or gender minority (SGM) people have disproportionately high rates of tobacco use - the number one cause of preventable death.
- Trial name
- NCT05365633
- Testing
- Empowerment activity-enhanced tobacco cessation assistance
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Bladder Cancer, Cervical Cancer
Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking
RATIONALE: Stop-smoking plans, including counseling and nicotine replacement therapy, may help smokers quit smoking. It is not yet known whether counseling and the nicotine lozenge is more effective than counseling and the…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00365508
- Testing
- nicotine lozenge, nicotine patch
- Where
- 10 sites in United States
- Volunteers
- 642 people
- Sponsor
- Fox Chase Cancer Center
Tobacco Use Cessation, Tobacco Use Disorder
Progesterone & Postpartum Relapse to Smoking
The primary goal of this project is to investigate the potential efficacy of exogenous progesterone (with supplemental relapse prevention counseling) on postpartum relapse in new mothers.
- Trial name
- NCT01798394
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Dependence, Smoking Cessation
Use of Varenicline for 4-weeks Prior to Quitting
Varenicline (Champix) is a relatively new medicine that is effective in helping people to quit smoking. It is normally started 1-week before stopping smoking and used for up to 12-24 weeks.
- Trial name
- NCT00789074
- Testing
- Varenicline
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Tobacco Use in Childbirth, Smoking Cessation
Fish Oil to Reduce Tobacco Use iN Expectant Mothers Study
The purpose of this feasibility study is to obtain pilot data in preparation for an upcoming R01 submission. The goals of that submission will be to conduct a clinical trial of n-3 LCPUFAs for smoking cessation in pregnant women.
- Conditions
- Tobacco Use in Childbirth, Smoking Cessation, Pregnancy Related
- Trial name
- FORTUNE (NCT03077724)
- Testing
- Fish oil
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Smoking Cessation, Nicotine Addiction
Innovative Digital Therapeutic for Smoking Cessation
This study is comparing the efficacy of two smoking cessation apps.
- Conditions
- Smoking Cessation, Nicotine Addiction, Drug Addiction, Drug Dependence
- Trial name
- NCT03694327
- Testing
- CT-101-M, QuitGuide
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- My Digital Study
Cigarette Smoking
E-Cigarettes and Financial Incentives to Promote Tobacco Harm Reduction Among Adults Accessing Shelter Services
This randomized controlled trial evaluated the feasibility and potential efficacy of 1) e-cigarette switching (EC) or 2) e-cigarette switching + financial incentives for combustible cigarette cessation (EC+FI)
- Trial name
- EXCHANGE (NCT03743532)
- Testing
- E-cigarette Switching, Financial Incentives
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation, Smoking, Cigarette
Enhancing Self Regulation Among Smokers
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to smoking cues in individuals with nicotine dependence.
- Conditions
- Smoking Cessation, Smoking, Cigarette, Nicotine Dependence
- Trial name
- MIMIC (NCT04161144)
- Testing
- sirolimus
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Medical University of South Carolina
Cocaine Dependence, Methamphetamine Dependence
Smoking-Cessation and Stimulant Treatment (S-CAST)
The primary objective of this study is to evaluate the impact of substance-abuse treatment as usual plus smoking-cessation treatment (TAU+SCT), relative to substance-abuse treatment as usual (TAU), on drug-abuse outcomes.
- Conditions
- Cocaine Dependence, Methamphetamine Dependence, Nicotine Dependence
- Trial name
- S-CAST (NCT01077024)
- Testing
- Smoking-cessation treatment
- Where
- 12 sites in United States
- Volunteers
- 538 people
- Sponsor
- University of Cincinnati
Tobacco Use Disorder
Innovative Interventions for Smoking Cessation
The purpose of this study is to evaluate the effect of a combination of the 21 mg nicotine patch and very low nicotine content (VLNC) cigarettes compared to 21 mg nicotine patch only and very low nicotine content cigarette only…
- Trial name
- NCT01050569
- Testing
- Nicotine Patch, VLNC Cigarette, VLNC Cigarette Plus Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use Disorder, Smoking Cessation
Deep rTMS and Varenicline for Smoking Cessation
The purpose of this study is to investigate the effect of deep repetitive transcranial magnetic stimulation (rTMS) using the insula H-coil on smoking outcomes in smokers receiving varenicline.
- Trial name
- NCT04083144
- Testing
- Deep Repetitive Transcranial Magnetic Stimulation (Active), Varenicline
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre for Addiction and Mental Health
Nicotine Dependence
Combination Bupropion / Varenicline for Smoking Cessation in Male Smokers
Previous results from the investigators' Center have shown that combination treatment with Chantix and Zyban is more successful in helping men quit smoking. The investigators hope to replicate these findings with this study.
- Trial name
- ConNic5 (NCT01806779)
- Testing
- Chantix, Zyban, Nicotine patches
- Where
- 4 sites in United States
- Volunteers
- 376 people
- Sponsor
- Duke University
Smoking, Smoking Cessation
Connect to Quit for Smoking
The purpose of this research study is to examine the effectiveness of an intervention designed to reduce smoking in low income veterans within a regional United States Veterans Administration(VA) health care system.
- Trial name
- CTQ (NCT01299896)
- Testing
- Coordinated Care, Usual Care
- Where
- United States
- Volunteers
- 633 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Nicotine Dependence, Cigarette Smoking
New Approaches to Smoking Cessation in Heavy Drinkers
The purpose of this study is to develop and test an integrated cognitive-behavioral intervention for smoking and alcohol among heavy drinking smokers.
- Conditions
- Nicotine Dependence, Cigarette Smoking, Alcohol Consumption, Heavy Drinking
- Trial name
- NCT02151591
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Pulmonary Disease, Chronic Obstructive, Cigarette Smoking
E-Visit for COPD and Smoking Cessation
The goal of this work is to develop, refine, and pilot test an electronic visit (e-visit) to: 1) deliver smoking cessation treatment to adults at risk for COPD and 2) to improve rates of COPD early detection and accurate…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Cigarette Smoking, Telemedicine
- Trial name
- NCT04155073
- Testing
- smoking cessation, early COPD detection, electronic visit, Treatment As Usual
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Medical University of South Carolina
Tobacco Use Cessation
Improving Quitline Support Study
This study seeks to evaluate ways to improve outcomes for low-education, uninsured or Medicaid-eligible smokers who do not successfully quit with standard telephone quit line treatment.
- Trial name
- IQS (NCT03538938)
- Testing
- 1-Call Quitline Counseling, 4-Call Quitline Counseling, Nicotine patch
- Where
- United States
- Volunteers
- 1,316 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Tobacco Use
A Mobile App Based Cognitive Dissonance Intervention for Smoking Cessation
This research study aims to develop a cognitive dissonance-based mobile app for smoking cessation (Support2Quit) and test the efficacy of the app with 500 adult smokers who express a desire to quit smoking.
- Trial name
- Support2Quit (NCT05797155)
- Testing
- Support2Quit App - Cognitive Dissonance Based Smoking Cessation + Smoking Cessation Tips, Tips for Smoking Cessation App
- Where
- United States
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Cigarette Smoking
Smoking, Stress, HIV and Mobile Technology
The present investigation aims to address disparities in cigarette use outcomes among Black/African American adults with HIV. The specific aims of this study are: (1) To modify a recently developed, culturally adapted, mobile…
- Trial name
- NCT05709002
- Testing
- MASP+, Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Houston
Tobacco Use Disorder, Smoking Cessation
Pharmacogenetics, Emotional Reactivity and Smoking
The goals of this placebo-controlled randomized clinical trial were to evaluate the differences in emotional reactivity (peak startle response to affective stimuli) during a cessation attempt among smokers treated with bupropion…
- Trial name
- NCT00507728
- Testing
- Bupropion, Varenicline, Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 646 people
- Sponsor
- M.D. Anderson Cancer Center
Nicotine Dependence, Smoking Cessation
Accelerated iTBS in Smoking Cessation
Cigarette smoking is one of the foremost causes of preventable disease and premature death. In 2014, 68% of adult smokers wanted to quit smoking and in 2017, 55.1% of adult smokers had made a quit attempt.
- Trial name
- NCT05271175
- Testing
- Active intermittent theta burst stimulation
- Where
- Cyprus
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cyprus rTMS Center