Clinical trials: Tomography
Acute Respiratory Failure (ARF), Hypertension
EIT Evaluation of Different Antihypertensive Agents on the Ventilation-Perfusion Ratio in Patients With Acute Respiratory Failure
This prospective, single-center interventional study aims to evaluate the effect of two commonly used intravenous antihypertensive agents - nicardipine and nitroglycerin - on lung ventilation-perfusion (V/Q) distribution in…
- Conditions
- Acute Respiratory Failure (ARF), Hypertension, Pulmonary Perfusion Imbalance, Aortic Dissection (Subset)
- Trial name
- NCT07603037
- Testing
- Nitroglycerin, Nicardipine
- Where
- China
- Volunteers
- 12 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Prostate Cancer (Diagnosis), Prostate-specific Membrane Antigen
Intratumoral Heterogeneity on [18F]PSMA and [18F]FDG PET/CT in Predicting Invasion and Prognosis of Prostate Cancer
The purpose of this study is to analyze heterogeneity of prostate cancer（PCa）based on the head-to-head imaging of prostate-specific membrane antigen (PSMA) and fluorodeoxyglucose (FDG) positron emission tomography computed…
- Conditions
- Prostate Cancer (Diagnosis), Prostate-specific Membrane Antigen, Positron Emission Tomography (PET)
- Trial name
- NCT06919159
- Testing
- PSMA PET/CT scan, FDG-PET
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Jiequn Yu
Alzheimer´s Disease
Positron Emission Tomography (PET) Study With [11C]AZD2995 and [11C]AZD2184, Candidate PET Ligands for β Amyloid
The study is carried out in order to investigate if [11C]AZD2995, compared to [11C]AZD2184, is a more suitable PET ligand for in vivo imaging of β amyloid depositions in the human brain.
- Trial name
- PET (NCT00692705)
- Testing
- Radioligand (11C)AZD2995, Radioligand (11C)AZD2184
- Where
- Sweden
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Tumors
18F-Fluorodeoxyglucose Positron Emission Tomography in Oncology and Neurology
This clinical trial is being conducted to study the use of a radioactive glucose tracer as an imaging test [Positron Emission Tomography (PET)scan] in adults who have or are suspected of having cancer and in another group of…
- Trial name
- NCT01180751
- Testing
- [18F]-Fluorodeoxyglucose
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- University of Manitoba
Abdominal Pain, Acute Pain
Diagnostic Performance of Low-Dose CT for Acute Abdominal Conditions
The goal of this non-inferiority observational study is to assess the diagnostic performance of low-dose CT with deep learning image reconstruction (DLIR) in adult participants with acute abdominal conditions.
- Conditions
- Abdominal Pain, Acute Pain, Acute Cholecystitis, Acute Appendicitis
- Trial name
- DETECT_Acute (NCT05651360)
- Testing
- low-dose CT
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 246 people
- Sponsor
- Oslo University Hospital
Mild Cognitive Impairment
Beta-Amyloid Imaging With [18F]NAV4694 PET in Predicting Progression to AD in Subjects MCI
To investigate whether [18F]NAV4694 positron emission tomography (PET) scan findings have the ability to distinguish subjects with mild cognitive impairment (MCI) who progress to Alzheimer's disease (AD) from those who do not.
- Trial name
- NAV4-04 (NCT01812213)
- Testing
- [18F]NAV4694
- Where
- 11 sites in United States
- Volunteers
- 76 people
- Sponsor
- Navidea Biopharmaceuticals
Spaceflight Associated Neuro-Ocular Syndrome, SANS
The Eye in Orbit: UCF Adaption
The goal of this study is to understand the impact of space travel on the eyes. Space flight impacts numerous aspects of ocular anatomy and physiology.
- Trial name
- NCT06092359
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Central Florida
Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth
A Comparative Clinical Study Assessing Dentin Thickness and Discoloration in Deep Carious Lesions Treated With Biodentine Alone Versus Diode Laser Pre-treatment Followed by Biodentine
This interventional clinical study aims to compare dentin thickness preservation and tooth discoloration in deep carious lesions treated with Biodentine alone versus diode laser pre-treatment followed by Biodentine.
- Conditions
- Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth, Deep Carious Lesion
- Trial name
- NCT07358442
- Testing
- Biodentin, Diode laser
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Misr International University
Chronic Obstructive Pulmonary Disease (COPD)
Effect on Structural Changes in Airways, Measured by MSCT, of Twice Daily 60mg AZD9668 for 12 Weeks in Chronic Obstructive Pulmonary Disease (COPD) Patients
The primary objective of the study is to evaluate structural changes effected by AD9668 in the airways of adults with Chronic Obstructive Pulmonary Disease (COPD) by Multi-Slice Computed Tomography (MSCT)
- Trial name
- NCT01054170
- Testing
- AZD9668
- Where
- 9 sites in Canada, Denmark and 3 more
- Volunteers
- 52 people
- Sponsor
- AstraZeneca
Cardiovascular Diseases
Effect of a PPAR-Alpha Agonist on the Age Related Changes in Myocardial Metabolism and Mechanical Function
The purpose of this study is to determine if treatment with a drug called fenofibrate, which is a PPAR-alpha agonist and controls how the heart metabolizes fats, will reverse the age-related decline in cardiac fat metabolism and…
- Trial name
- PPAR (NCT00627653)
- Testing
- fenofibrate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Acute Abdomen in Children
Role of Multidetector Computerized Tomography (MDCT) in Diagnosis of Non Traumatic Acute Abdomen in Pediatric Age Group.
To evaluate the role of MDCT in diagnosis of non traumatic causes of acute abdomen in pediatric patients with clinical and surgical correlation.
- Trial name
- NCT04480983
- Testing
- Multidetector Computerized Tomography (MDCT)
- Volunteers
- 50 people
- Sponsor
- Amal Fathy Abo Elgarad
Lymphedema, Secondary Lymphedema
Feasibility of Lymph Edema-induced Reticulation Subtraction Based on Computerized Tomography
Development of lympho-proliferation reticulation quantification using CT.
- Conditions
- Lymphedema, Secondary Lymphedema, CT
- Trial name
- NCT03523494
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Ulsan University Hospital
Coronary Artery Disease, Hypercholesterolemia
A Trial Assessing the Effectiveness of Evolocumab in Reducing the Plaque Burden in Participants With Subclinical Atheroma
The main aim of this trial is to demonstrate that Evolocumab plus routine lipid management is superior to routine lipid management alone in modifying plaque (non-calcified) volume as measured by Artificial Intelligence-enabled…
- Conditions
- Coronary Artery Disease, Hypercholesterolemia, Atheroma, Atherosclerotic Plaque
- Trial name
- NCT07803679
- Testing
- Evolocumab, Routine Lipid Management, Autoinjector
- Volunteers
- 308 people
- Sponsor
- Amgen
Positron-Emission Tomography
The Performance of Multi-tracer Multimodality PET in Lymphoma
Investigating the performance of Multi-tracer Multimodality PET in lymphoma
- Trial name
- NCT05004961
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Cancer Hospital & Institute
Lung Cancer Screening
Clinical Evaluation of the Lung Cancer AI-based Decision Support Tool in Low-Dose Lung CT
The goal of this observational study is to clinically validate the accuracy of an AI-based decision support tool-the Lung Cancer Detection System (LCDS)-for detecting lung nodules in asymptomatic adults aged 50-79 with a history…
- Trial name
- GenMedAILCSD1 (NCT07052773)
- Testing
- Lung Cancer Detection System (LCDS)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Genesis Medical AI
Myopia, Perfusion; Complications
OCTA Analysis of Macular and Papillary Perfusion After Refractive Surgery in Myopes
Refractive surgery for correction of myopia is very common nowadays. However, various refractive techniques may be associated with increase in the IOP, especially during flap creation.
- Trial name
- NCT04424069
- Testing
- Refractive surgery
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Coronary Artery Disease
Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease
The primary hypothesis is that computed tomography (CT) is superior to invasive coronary angiography (ICA) concerning the primary endpoint MACE (MACE = major adverse cardiovascular event; defined as at least one of the following…
- Trial name
- DISCHARGE (NCT02400229)
- Testing
- Computed tomography angiography (cardiac CT), Invasive coronary angiography (ICA)
- Where
- 20 sites in Austria, Czechia and 13 more
- Volunteers
- 3,546 people
- Sponsor
- Charite University, Berlin, Germany
Dental Caries
The Effectiveness of iTero Element 5D NIRI System in Early Proximal Caries Detection in Permanent Teeth
As a new emerging technology for the diagnosis of dental caries, near-infrared imaging requires further research and validation to determine its effectiveness.
- Trial name
- NCT06276959
- Testing
- intraoral scanning, clinical oral examination, cone-beam computed tomography
- Where
- China
- Volunteers
- 120 people
- Sponsor
- West China College of Stomatology
Coronary Artery Disease
Coronary Artery and Coronary Artery Bypass Graft Imaging Using a Specialized Catheter and Computed Tomography
The present study relates to a new approach to coronary artery and coronary artery by-pass graft imaging, and more particularly to computed tomographic angiography following an aortic root injection of a low amount of contrast…
- Trial name
- NCT00474565
- Testing
- Placement of an aortic root pigtail catheter.
- Where
- United States
- Sponsor
- Corewell Health East
Mammography, Breast Cancer
Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening
Brief Summary A task like breast cancer screening (mammography) can be described as a "hybrid search" task. In basic visual search tasks, observers search for a target among distractors that are not the target.
- Conditions
- Mammography, Breast Cancer, Radiology
- Trial name
- NCT05975736
- Testing
- Search only for masses, Search only for calcifications, Search for both together
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital