Clinical trials: Tongue Diseases
Bladder Cancer, Cervical Cancer
Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking
RATIONALE: Stop-smoking plans, including counseling and nicotine replacement therapy, may help smokers quit smoking. It is not yet known whether counseling and the nicotine lozenge is more effective than counseling and the…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00365508
- Testing
- nicotine lozenge, nicotine patch
- Where
- 10 sites in United States
- Volunteers
- 642 people
- Sponsor
- Fox Chase Cancer Center
Erythema Migrans
Patient's Pretreatment Expectations About Post-Lyme Symptoms
The investigators will focus on pretreatment expectations of patients with early Lyme disease manifested as erythema migrans with the aim of assessing the association between pretreatment expectations quantified with a…
- Trial name
- NCT03462329
- Testing
- Antibiotics (preferentially oral doxycycline 100 mg bid)
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Asthma
Multimodal Tongue-Pulse Information Fusion for Syndrome Diagnosis and Cohort Study in Children With Asthma
Asthma is one of the most prevalent chronic respiratory diseases in children, and accurate phenotyping and disease monitoring remain challenging in routine clinical practice.
- Trial name
- NCT07383883
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Children's Medical Center
Malocclusion, Angle's Class
Comparison of Two Types of Lingual Fixed Retainer Fabricated
This study includes patients who have had previous orthodontic treatments (without tooth extraction) and who have good alignment of their lower incisors. Investigators will compare two types of lingual retainers made with CAD-CAM
- Trial name
- malocclusion (NCT06244810)
- Testing
- Lingual retainer from Fiber, Lingual retainer from metal, Traditional retianer from braided
- Where
- Syria
- Volunteers
- 42 people
- Sponsor
- Hama University
Chronic Obstructive Pulmonary Disease
Decreased Tongue Strength is Related to Skeletal Muscle Mass in COPD Subjects
Background: Dysphagia is frequently observed in subjects with chronic obstructive pulmonary disease (COPD). But tongue strength has not been investigated yet in COPD subjects.
- Trial name
- NCT04761380
- Testing
- balloon-based tongue pressure measurement device
- Where
- Japan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Kindai University
Sjögren's Syndrome, Systemic Lupus Erythematosus
Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome
To explore the association among TCM pattern, TCM tongue diagnosis and TCM pulse diagnosis for Autoimmune disease and Dry eye syndrome
- Conditions
- Sjögren's Syndrome, Systemic Lupus Erythematosus, Rheumatoid Arthritis, Systemic Sclerosis
- Trial name
- NCT03937271
- Testing
- Traditional Chinese Medicine pattern, Traditional Chinese Medicine tongue diagnosis, Traditional Chinese Medicine pulse diagnosis
- Where
- Taiwan
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Burning Mouth Syndrome, Glossodynia
Evaluation of the Effectiveness of the Selected Method of Treatment of Primary Burning Mouth Syndrome
The burning mouth syndrome (BMS) is a chronic pain syndrome of the oral mucosa. Feels like experiencing a burning sensation, pain, stinging, or numbness in the mouth along with a feeling of dryness, paraesthesia, taste…
- Trial name
- NCT04884503
- Testing
- Clonazepam tablets, tongue pads
- Where
- Poland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Sjögren's Syndrome
DNA Exome Sequencing TCM for Sjögren's Syndrome
To explore the association among gene, TCM pattern, TCM tongue diagnosis and TCM pulse diagnosis with the DNA Exome sequencing tools for Sjögren's syndrome
- Trial name
- NCT03935373
- Testing
- DNA Exome sequencing, Oral microbiome, Proteomics
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Head and Neck Cancer, Mucositis Oral
GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer
GM-CSF may protect normal cells from the side effects, such as mucositis, of radiation therapy and may help damaged tissue heal faster after radiation therapy.
- Conditions
- Head and Neck Cancer, Mucositis Oral, Radiation Toxicity, Tongue Cancer
- Trial name
- NCT00293462
- Testing
- sargramostim, oral salt and soda mouthwash
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Marilyn Dodd
Burning Mouth Syndrome
A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome
This is a case control study of the association between burning mouth syndrome and sleep dysfunction. Cases will comprise of patients diagnosed with burning mouth syndrome at the UCSF oral medicine clinic.
- Trial name
- NCT00862576
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, San Francisco
Ankyloglossia, Breastfeeding
Anterior Lingual Frenectomy is Inadequate in Improving Breastfeeding Outcomes: a Prospective Cohort Study
A previously published study (https://www.ncbi.nlm.nih.gov/pubmed/27641715) identified breastfeeding improvements following lingual frenotomy and/or maxillary labial frenectomy.
- Trial name
- NCT02936518
- Testing
- Lingual frenotomy and/or maxillary labial frenectomy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The Oregon Clinic
Hypopharyngeal Cancer
Neoadjuvant Chemotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck (SCCHN)
The investigators will examine whether 2-cycles of DFP chemotherapy before definitive concurrent chemoradiation therapy (CCRT) can improve progression-free survival in locally advanced (Stage III \& IVM0) hypopharyngeal and base…
- Trial name
- NCT01312350
- Testing
- neoadjuvant docetaxel/cisplatin/fluorouracil, No treatment before definitive CCRT
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Erythema Migrans
Inflammatory Responses in Solitary and Multiple Erythema Migrans
The investigators will evaluate differences in host immune responses (levels of cytokines and chemokines, representative of innate, Th1, and Th17 immune responses) in acute sera from adult patients with solitary or multiple…
- Trial name
- NCT03980015
- Testing
- antibiotic treatment
- Where
- Slovenia
- Volunteers
- 134 people
- Sponsor
- University Medical Centre Ljubljana
Laryngopharyngeal Reflux, Hypertrophy of Lingual Tonsil
Dexlansoprazole to Treat Laryngopharyngeal Reflux and Lingual Tonsil Hypertrophy
Main Hypothesis: The investigators hypothesize that measurements of lingual tonsil tissue (LTT) thickness will decrease following treatment with once daily oral dexlansoprazole 60 mg in patients diagnosed with laryngopharyngeal…
- Trial name
- NCT01328652
- Testing
- dexlansoprazole
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Advanced Center for Specialty Care
Malignant Neoplasms of Lip Oral Cavity and Pharynx, Oropharyngeal Cancer
Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer
The goal of this clinical research study is to compare the use of MRI simulations to plan different doses of intensity modulated radiotherapy (IMRT) to the standard IMRT dose in patients with low risk human papilloma virus…
- Trial name
- NCT03224000
- Testing
- Modified Barium Swallow (MBS), Swallowing Questionnaire, Symptom Questionnaire
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- M.D. Anderson Cancer Center
Dysphagia
Motor Imagery Exercise and Tongue Strength
This research study is a six-week treatment pilot study to compare the effects of different exercise types on measures of tongue strength and swallowing pressure in typically aging older adults.
- Trial name
- NCT03423095
- Testing
- Active Jaw Exercise with Relaxation, Active Tongue Exercise, Active Tongue Exercise + Mental Practice
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Head and Neck Cancer, Infection
Study of Nutrition Regimens in Treating Patients With Cancer of the Upper Aerodigestive Tract
RATIONALE: It is not yet known which regimen of enteral nutrition is more effective in preventing infections in patients undergoing surgery for cancer of the upper aerodigestive tract.
- Conditions
- Head and Neck Cancer, Infection, Malnutrition
- Trial name
- NCT00765440
- Testing
- therapeutic nutritional supplementation
- Where
- France
- Volunteers
- 311 people
- Sponsor
- Centre Antoine Lacassagne
Burning Mouth Syndrome
Neurogenic Mechanisms in Burning Mouth Syndrome
Burning mouth syndrome (BMS) is characterized by a bilateral burning sensation in the anterior tongue, hard palate and lips in the absence of any clinical or laboratory findings.
- Trial name
- BMS17 (NCT00875537)
- Testing
- Capsaicin oral gel 0.025%, Capsaicin oral gel 0.01%
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Side Effects, Tonsil Hypertrophy
Tonsillar Retractor-induced Subacute Submassive Tongue Edema
This study aimed to detect tongue edema induced by the pressure exerted by tonsillar retractor; edema detection was made through tongue area measurement using ultrasonography (USG) in pediatric patients who underwent…
- Conditions
- Side Effects, Tonsil Hypertrophy, Children, Only
- Trial name
- NCT04204681
- Testing
- Ultrasonography imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Selcuk University
Stage I Squamous Cell Carcinoma of the Oropharynx, Stage II Squamous Cell Carcinoma of the Oropharynx
Patient Preferences in Making Treatment Decisions in Patients With Stage I-IVA Oropharyngeal Cancer
This pilot research trial studies patient preferences in making treatment decisions in patients with stage I-IVA oropharyngeal cancer.
- Conditions
- Stage I Squamous Cell Carcinoma of the Oropharynx, Stage II Squamous Cell Carcinoma of the Oropharynx, Stage III Squamous Cell Carcinoma of the Oropharynx, Stage IVA Squamous Cell Carcinoma of the Oropharynx
- Trial name
- NCT01949740
- Testing
- questionnaire administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Chicago