Clinical trials: Tonsillectomy
Tonsillectomy
Dexamethasone-bupivacaine Versus Bupivacaine for Tonsillectomy Pain.
Investigators compared in this study peritonsillar infiltration of bupivacaine %0.5 (n=40 participants) versus bupivacaine % 0.5 and dexamethasone (number 40participants ) before surgery for reduce posttonsillectomy pain.And…
- Trial name
- NCT03443778
- Testing
- Bupivacaine 0.5%, Bupivacaine 0.5% , Dexamethasone, Nacl 0,9 %
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Dexmedetomidine, Lidocaine
A Comparative Study to Measure the Effect of Nebulized Dexmedetomidine
A comparative study to measure the effect of nebulized dexmedetomidine - lidocaine for controlling postoperative pain after tonsillectomy in adults.
- Conditions
- Dexmedetomidine, Lidocaine, Tonsillectomy
- Trial name
- NCT05158348
- Testing
- Dexmedetomidine Hydrochloride, Nebulized lidocaine, Local infiltration of lidocaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Tonsillectomy, Pain
Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy
Betamethasone is currently given routinely in conjunction with tonsillectomy surgery at the majority of Ear, Nose \& Throat clinics in Sweden.
- Conditions
- Tonsillectomy, Pain, PONV, Bleeding
- Trial name
- NCT03783182
- Testing
- Betamethason Sodium Phosphate, 10% glucose solution
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Umeå University
Pain, Postoperative, Obstructive Sleep Apnea of Child
Use of Analgesics and Pain Scores After Pediatric Adenotonsillectomy
The purpose of the study is to quantify the use of pain medications given to children aged 3 - 12 years as well as their pain level through pain scores after they have undergone a tonsillectomy or adenotonsillectomy surgery at…
- Trial name
- NCT04349397
- Testing
- Medication Tracking Form
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
IgA Nephropathy
Effect of Tonsillectomy on Longterm Renal Outcome of IgA Nephropathy
The effect of tonsillectomy therapy on IgA nephropathy is still controversial.Few prospective,randomized investigations have examined how tonsillectomy affects the shortterm and longterm renal outcome of IgA nephropathy.This is A…
- Trial name
- NCT02471599
- Testing
- tonsillectomy, non-tonsillectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Post Tonsillectomy Pain, Post Operative Analgesia
Transnasal Sphenopalatine Ganglion Block for Postoperative Pain and Recovery in Tonsillectomy (TONwoPA)
The aim of this clinical trial is to evaluate the effectiveness of transnasal transmucosal sphenopalatine ganglion block in reducing post-tonsillectomy pain.
- Conditions
- Post Tonsillectomy Pain, Post Operative Analgesia, Opioid Consumption, Sphenopalatine Ganglion Block
- Trial name
- TONwoPA (NCT07370129)
- Testing
- Transnasal Transmucosal Sphenopalatine Ganglion Block, Lidocaine %5, Saline (0.9% NaCl)
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ankara University
Tonsillectomy
Role of Antibiotics Post Tonsillectomy
morbidity after tonsillictomy remains asignificant problem therefore they recommend prophylactic antibiotics to reduce it.in the other hand, the overuse of antimicrobial agents can lead to antimicrobial resistance ,adverse drug…
- Trial name
- NCT03491085
- Testing
- Amoxicillin/clavulanate
- Volunteers
- 200 people
- Sponsor
- Assiut University
Sleep Apnea, Obstructive, Child
Effect of CPAP and Adenotonsillectomy in Upper Airway Volume of Children With OSAS
Obstructive sleep apnea syndrome (OSAS) in children has high prevalence and severe complications, and its first line of treatment (adenotonsillectomy) has risk of complications.
- Conditions
- Sleep Apnea, Obstructive, Child, Continuous Positive Airway Pressure, Adenoidectomy
- Trial name
- NCT03169491
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Post Operative Pain
Peri Tonsillar Infiltration of Ketamine or Bupivacaine for Post Tonsillectomy Analgesia
Comparison between the analgesic effect of local infiltration of either Bupivacaine or ketamine in the peritonsillar area before the incision of tonsillectomy to achieve postoperative analgesia
- Trial name
- NCT05341323
- Testing
- Ketamine., Bupivacaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Analgesic Adverse Reaction
Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy
This prospective, randomized, double blinded study is designed to compare the bleeding rates of ketorolac vs. placebo when used for post tonsillectomy pain control in pediatric patients ages 2-18.
- Trial name
- NCT03453541
- Testing
- Ketorolac Tromethamine, 0.9% Normal Saline
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Laryngopharyngeal Reflux, Throat Pain
Anti-reflux Control to Decrease Post Tonsillectomy Pain
The study aims to determine if treating pediatric patients (age 7-17) for four weeks with omeprazole prior to tonsillectomy will decrease post tonsillectomy pain.
- Trial name
- NCT01777854
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Post Operative Pain
The Effectiveness of Local Infiltration Technique in Adult Tonsillectomy
Tonsillectomy is commonly associated with postoperative pain. The modified pre-incision infiltration of anesthetic mixture combined with general anesthesia was shown to decrease post-tonsillectomy pain in children.
- Trial name
- NCT03806335
- Testing
- Infiltration, General anesthesia
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Tonsillar Disorder
Fasting Time and Post-tonsillectomy Pain
This is a prospective, observational study to determine the association between preoperative fasting duration and post-tonsillectomy pain scores in the post-anesthesia care unit (PACU) among pediatric patients undergoing…
- Trial name
- NCT07574476
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Brittany Willer
Tonsillitis Recurrent, Tonsillitis Chronic
Tonsil Surgery in Recurrent or Chronic Tonsillitis
Tonsil surgery is common in adults with recurrent or chronic tonsillitis. The surgical techniques include either partial or total surgical removal of the palatal tonsils (tonsillotomy, TT, and tonsillectomy, TE, respectively).
- Trial name
- NCT04657549
- Testing
- Tonsillectomy, Tonsillotomy
- Where
- 7 sites in Finland
- Volunteers
- 147 people
- Sponsor
- Oulu University Hospital
Tonsillectomy, Pharyngoplasty
Suzetrigine in Tonsillectomy for Opioid-sparing Pain Management
The goal of this clinical trial is to learn if a non-opioid pain medicine called suzetrigine can lower how much opioid pain medicine adults need after tonsil surgery (tonsillectomy) or a similar throat surgery.
- Conditions
- Tonsillectomy, Pharyngoplasty, Suzetrigine, Opioid
- Trial name
- STOP (NCT07821931)
- Testing
- Suzetrigine, Acetaminophen, oxycodone
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Stanford University
Tonsillectomy
Safety and Efficacy of Intravenous Ibuprofen for Treatment of Pain in Pediatric Patients Undergoing Tonsillectomy
The hypothesis is that a single, pre-operative dose of intravenous ibuprofen will significantly reduce post-operative fentanyl use compared to placebo.
- Trial name
- NCT01332253
- Testing
- Intravenous ibuprofen, Normal Saline
- Where
- 6 sites in United States
- Volunteers
- 161 people
- Sponsor
- Cumberland Pharmaceuticals
Tonsillar Hypertrophy
Opioid-sparing Effect of Intranasal Dexmedetomidine
Background: Management of postoperative pain in paediatric patients undergoing tonsillectomy remains a challenge that faces anesthesiologists in their daily practice.
- Trial name
- NCT05848505
- Testing
- Dexmedetomidine
- Where
- United Arab Emirates
- Volunteers
- 50 people
- Sponsor
- Pierre-Yves P Lequeux
Tonsillectomy
Suprazygomatic Nerve Block in Tonsillectomy Patients
The use of suprazygomatic maxillary nerve block to reduce postoperative pain and hospital stay is greater than the use of NSAID and opioids.
- Trial name
- NCT06359925
- Testing
- Suprazygomatic maxillary nerve block using dexmedetomidne and Bupivacaine, Suprazygomatic maxillary nerve block using Bupivacaine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Tonsillectomy, Children
Closure Method Study Following Tonsillectomy in Children
This is a children's study evaluating the effects of a tonsillectomy with tonsillar fossae closure compared to without closure of the operative wound.
- Trial name
- NCT00730340
- Testing
- Closure of the Tonsillar Fossa, Tonsillectomy with open fossa
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Oklahoma
Analgesia
Post Tonsillectomy Analgesia Comparison After Surgery Site Spray of Local Anesthesics
Check analgesia after tonsillectomy in adults
- Trial name
- NCT04325113
- Testing
- levobupivacaine
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- University of Liege