Clinical trials: Tooth
Dental Caries
Comparative Study of Experimental Dental Adhesive With and Without Phosphoric Acid Pretreatment
The intent of this study is to evaluate the clinical performance of an experimental dental bonding agent for use with dental restorative composites with and without pretreatment of the tooth dentin and enamel using phosphoric…
- Trial name
- NCT02071953
- Testing
- Experimental adhesive w/out phosphoric acid in post. rest., Experimental adhesive with phosphoric acid in post. rest.
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Children, Adult, Molar Incisor Hypomineralization
Effectiveness of Infiltration With Resin in Treatment of MIH Incisors in Children Showing Opacities
Enamel development defects are the result of a set of environmental, systemic and genetic causal agents that reveal a multifactorial etiology model, which in anterior teeth produces a serious aesthetic problem, converted into a…
- Conditions
- Children, Adult, Molar Incisor Hypomineralization, Dental Diseases, Opacity
- Trial name
- NCT05597956
- Testing
- white defects, yellow defects, brown defects
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- University of Valencia
Tooth Loss
An Observational Study of the T3 Pro Dental Implant System
A prospective, observational, multicenter study where 60 patients needing implants in the maxilla or mandible will be enrolled. The patients will be restored with a final prosthesis no later than 4 months following implant…
- Trial name
- Spike (NCT05498662)
- Testing
- T3 Pro dental implant system
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ZimVie
Cognitive Impairment, Frail Older Adults
Cognitive Fraility and Biomarkers in Older Patients
this study aimed to investigate the association between cognitive fraility and selected plasma and cerebrospinal fluid biomarkers related to neurodegenetaion and neuroinflammation in older adult patients undergoing elective…
- Conditions
- Cognitive Impairment, Frail Older Adults, Orthopaedic Surgery
- Trial name
- NCT07184073
- Testing
- assessment Mini mental state examination, assessment FRAIL scale, collecting cerebrospinal fluid during regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Baskent University
Dental Erosion
Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ Study
Healthy volunteers are observationally wearing an intraoral device with bovine tooth samples once for two hours. Afterwards, Calcium release from the bovine enamel and dentin samples is measured after extraoral erosion.
- Trial name
- NCT02780973
- Testing
- Wearing of an intraoral device with bovine tooth samples
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Malocclusions, Canine Retraction
Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction
To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison.
- Trial name
- NCT07455656
- Testing
- patients will receive local application of vitamin D3 combined with corticision
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Missing Teeth, Dental Implant
Comparison of Different Drilling Speed to Classify Bone Quality by Tactile Sensation on a Saw Bone Model
Comparison of different drilling speed to classify bone quality by tactile sensation on a saw bone model
- Trial name
- NCT03877419
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Root Resorption
The Effect of Two Different Types of Forces on Possible Root Resorption in Relation to Dentin Phosphoprotein Levels
External root resorption is a common unfavourable sequel of orthodontic treatment. Although diagnosis of root resorption is usually done by radiographs; they are technique sensitive.
- Trial name
- NCT04825665
- Testing
- Continuous force, Intermittent force
- Where
- 2 sites in Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sherifa Ghaleb
Dental Caries
Two Years Survival Rate of Class II ART Restorations in Primary Molars Using Two Ways to Avoid Saliva Contamination
AIM: To evaluate influence of two methods to avoid saliva contamination on the survival rate of atraumatic restorations in primary molars.
- Trial name
- NCT01924611
- Testing
- Atraumatic Restorative Technique using cotton rolls, Atraumatic Restorative Technique
- Where
- Brazil
- Volunteers
- 232 people
- Sponsor
- Federal University of Paraíba
Tooth Bleaching
Safety and Efficacy of a 6% Hydrogen Peroxide Tooth Bleaching Agent
Bleaching protocol In each session, volunteers received prophylaxis with pumice powder and water. Then, gingival tissue was protected using a light-cured resin gum barrier applied according to the manufacturer's instructions…
- Trial name
- NCT02353611
- Testing
- 6% hydrogen peroxide, 35% hydrogen peroxide
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Chile
Endodontic Disease, Root Canal Infection
3D Analysis of Root Canal Conformation
Aim To evaluate in vivo the shaping ability of the canal with 3 different single-file systems: Reciproc Blue, WaveOne Gold and XP Endo-Shaper, using cone beam computed tomography and 3D reconstructions to measure canal volume…
- Trial name
- NCT03680534
- Testing
- Root canal preparation
- Where
- Colombia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institucion Universitaria Colegios de Colombia
Dental Caries, Dental Plaque
Comparative Effectiveness of Various Educational Approaches on Oral Hygiene
Background: Dental caries constitutes a major global public health challenge, posing substantial burdens on both oral health outcomes and healthcare systems worldwide, with far-reaching implications for prevention, treatment, and…
- Trial name
- NCT06910501
- Testing
- Traditional oral hygiene instruction, Digital slide-based education, Brush DJ mobile appliaction
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ege University
Malocclusion, Open Bite
Anterior Open Bite Treatment With Bonded Spurs Associated With Build-ups Versus Conventional Bonded Spurs
This study compares the dentoalveolar and skeletal effects of bonded spurs associated with build-ups versus conventional bonded spurs in the early treatment of anterior open bite patients.
- Trial name
- NCT03702881
- Testing
- Bonded Spurs associated with posterior build-ups, Conventional bonded spurs
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Supernumerary Teeth
Prevalence of Erupted Supernumerary Teeth Among a Group of Egyptian Children Aged From Six to Fifteen Years Old
The purpose of this study is to assess the prevalence of erupted supernumerary teeth among a group of Egyptian children aged from 6-15 years old attending the Outpatients' clinic of Pediatric Dentistry and Dental Public Health…
- Trial name
- NCT03650634
- Where
- Egypt
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Health
Involving Parents to Improve Tooth Brushing for Autistic Children.
Parents of autistic children have reported a lack of understanding by oral health care staff around delivery of oral health preventive habits for their children.
- Trial name
- NCT06855693
- Testing
- Delivering better oral health: an evidence-based toolkit for prevention, Mini Mouth Care Matters guide for special Education Settings
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- Sussex Community NHS Foundation Trust
Acute Pain
Tramadol/Diclofenac Fixed-dose Combination Phase III Trial in Acute Pain After Third Molar Extraction
This study evaluated a new drug fixed-dose combination tablet (FDC) called tramadol/diclofenac at two different strengths (fixed doses of 25 milligrams [mg] of tramadol and of diclofenac or of 50 mg each).
- Trial name
- NCT03714672
- Testing
- Tramadol/Diclofenac 50/50, Tramadol/Diclofenac 25/25, Tramadol 50
- Where
- 8 sites in Mexico
- Volunteers
- 1,151 people
- Sponsor
- Grünenthal GmbH
Dental Anxiety
The Effects of Propranolol on Fear of Tooth or Molar Extraction
Randomized, placebo-controlled, double-blind, parallel group clinical trial evaluating the anxiolytic effects of propranolol on fear of wisdom tooth removal.
- Trial name
- NCT02268357
- Testing
- Propranolol
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pulpitis, Pulp Disease, Dental
Bioactive Materials in Pulp Therapy of Primary Teeth
The purpose of this study is to compare the clinical and radiographic success of a new injectable, fast setting bioceramic root repair material (BC RRM) putty with mineral trioxide aggregate (MTA) in pulpotomy procedures of…
- Trial name
- NCT04795830
- Testing
- Bioceramic root repair material as pulp dressing in pulpotomy in primary molars, Mineral Trioxide Aggregate as pulp dressing in primary molars (MTA)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries Extending Into Dentine
Digital Subtraction Radiography Evaluation of SMART Restoration With Partial Caries Removal in Primary Teeth
The objective of this study was to analyze the radiographic density of digital subtraction radiographs after SMART restoration with partial caries removal in primary molars at 6 and 12 months.
- Trial name
- DSR (NCT01749267)
- Testing
- partial caries removal only at enamel dentin junction.
- Where
- Thailand
- Volunteers
- 38 people
- Sponsor
- Mahidol University
Dental Caries in Children
Aesthetic Restorations in Deciduous Anterior Teeth
This study proposes to conduct a randomized clinical trial (RCT), composed of a sample of 194 deciduous central and lateral incisors with active cavitated lesions, simplified ICDAS C+ score, with involvement of more than two…
- Trial name
- NCT05875064
- Testing
- Restoration with resin composite and polyvinyl crown, Restoration with conventional resin composite
- Volunteers
- 194 people
- Sponsor
- University of Nove de Julho