Clinical trials: Tooth Caries
Caries, Dental, Health Behavior
Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children
This is a randomized clinical trial to test the efficacy of a parent-targeted text message-based intervention program on caries incidence and oral health behaviors (child and parent).
- Trial name
- iSmile (NCT03294590)
- Testing
- OHT Parent targeted text messages, CWT Parent targeted text messages
- Where
- United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Boston University
Dental Caries
Clinical Study on a New Flowable Composite as a Restorative in Adult Teeth
Study hypothesis: a new, low polymerization stress flowable composite performs no differently to a conventional, highly filled composite filling material when used as a restorative in small cavities in back teeth.
- Trial name
- NCT01369108
- Testing
- Flowable composite, Conventional composite restorative
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Solventum US LLC
Dental Caries
Dietary Influences On Caries Index Among Sudanese And Egyptian Adult Population
the objective of this study is to compare the caries index between Sudanese and Egyptian adult Population in patients with different diet habits and different oral hygiene state in range of (18-40) years old
- Trial name
- NCT03566953
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Silver Diamine Fluoride in Preventing Occlusal Caries in Primary Teeth
In Hong Kong, approximately half of the kindergarten children have dental caries (tooth decay) and the majority (>90%) of the decayed teeth were left untreated.
- Trial name
- NCT05084001
- Testing
- silver diamine fluoride, sodium fluoride varnish, tonic water
- Where
- China
- Volunteers
- 769 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries in Children
Comparative Study Between Smart Bur II and Traditional Carbide Bur in Selective Removal of Caries in Permanent Molars
A more biological and conservative technique of caries removal has emerged with minimally invasive restorative dentistry's advent. As a result, Smart Burs II has become a self-limiting, sensitive tool for removing caries.
- Trial name
- NCT06187259
- Testing
- caries removal by carbide bur, caries removal by polymer bur II
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Cardiac Disease, Dental Caries
Saliva Profiles in Children With Congenital Heart Disease
The purpose of this study was to evaluate whether there are relationships between the salivary oxidative stress status of children with CHD directly dental caries including gender, age, salivary flow rate, salivary pH, salivary…
- Trial name
- NCT03457974
- Testing
- saliva
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
HIV Infections
A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients
The purpose of this study is to examine how the level of HIV is reduced in the blood when anti-HIV therapy is initiated. This study will also evaluate whether adding GM-CSF or IL-12 to the anti-HIV drug regimen will increase the…
- Trial name
- NCT00000896
- Testing
- Indinavir sulfate, Lamivudine/Zidovudine, Hepatitis A Vaccine (Inactivated)
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cavity, Cavities of Teeth
In Vivo Assessment of the Tooth-Resin Composite Interface Using Optical Coherence Tomography
The aim of the study is to compare the short-term marginal integrity of two preparation techniques for Class I composite restoration using two visual assessment techniques, the FDI World Dental Federation and US Public Health…
- Trial name
- NCT05145322
- Testing
- Composite with 90 degree cavosurface angle, Composite with wide bevel
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Dental Caries in Children
Toothbrushing Program in Saudi Arabia "TOPS"
Project summary Introduction: Dental caries is a major oral health problem worldwide and is a particular public health challenge in Saudi Arabia. Dental caries cause pain, infection, and negatively impact quality of life.
- Trial name
- NCT05512156
- Testing
- Supervised Toothbrushing
- Where
- Saudi Arabia
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Dental Caries, Tooth Fractures
Comparison of Conventional and CAD/CAM Dental Restorations
Dental restorations (crowns, inlays or onlays) can be made conventionally or by CAD/CAM. The current literature is weak and does not separate the medical results of these two techniques.
- Conditions
- Dental Caries, Tooth Fractures, Tooth Resorption
- Trial name
- EVACFAOD (NCT02494427)
- Testing
- CAD/CAM manufactured fixed unitary dental prostheses, Conventionally manufactured unitary dental prostheses
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cavities of Teeth
Esthetics of Dental Composite and Adhesive System
To compare a newly developed filling composite to a current filling composite system. Two restorations will be placed in each subject, one using system A and one using system B.
- Trial name
- NCT03716349
- Testing
- Pulp vitality testing, Photos, local and/or topical anesthetic
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Erica Teixeira
Dental Caries
Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child
Aim: to examine caries occurrence in children who ten years ago received a mixture of probiotics during infancy. Hypothesis: the administration of probiotics during infancy has no effect on future dental health.
- Trial name
- NCT01424852
- Testing
- Probiotics in infant milk formula
- Where
- Finland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Turku
Dental Caries
Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining
The purpose of this study is to observe the effects of glass-ionomer cement (GIC) lining on risk of pulpal complications in deep occlusal cavities with resin-based restorations.
- Trial name
- NCT01567514
- Testing
- Glass ionomer cement lining
- Where
- Thailand
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Dental Caries
A Pilot Study to Promote Maternal and Infant Oral Health
The long term goals of this project are to develop and implement a combined prenatal and postnatal intervention to decrease early childhood caries. The program is based on risk assessment, diet intervention and counseling.
- Trial name
- NCT00719238
- Testing
- Nutrition plus education, Education only
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- UConn Health
Early Childhood Caries, Dental Caries
Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project
The purpose of this study is to determine whether a bundled best practices oral health intervention utilizing motivational interviewing versus a didactic maternal and child healthy lifestyle intervention will reduce childrens'…
- Trial name
- NCT04556175
- Testing
- Oral Health, Healthy Lifestyle
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Anxiety, Dental, Dental Decay
A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
This study will compare the post sedation events from three different multi-drug oral sedation regimens in order to help pediatric dentists determine the best course of action for their patients and prepare parents appropriately…
- Trial name
- NCT05126459
- Testing
- Regimen 1, Regimen #2, Regimen #3
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Loma Linda University
Dental Caries
Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries
The goal of this clinical trial is to learn if polymer-induced liquid precursor (PILP) can be used safely to treat dentin caries (cavities) in adults.
- Trial name
- NCT06727110
- Testing
- PILP Cement, PILP Conditioner
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
White Spot Lesions[Initial Caries]on Smooth Surface of Tooth
Remineralization Effect of βTricalcium Phosphate Nanoparticles Versus FunctionalizedβTricalcium Phosphate Nanoparticles
The study collects Sixty non carious sound human permanent premolars from Tanta University's maxillofacial surgery department. The teeth are cleaned and prepared, and randomly assigned into four groups.
- Trial name
- NCT06561789
- Testing
- Functionalized Nano ᵦ tricalcium phosphate particles, Nano ᵦ tricalcium phosphate particles, sodium fluoride mouth wash
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aya Magdy Elsadany
Dental Caries in Children
Potential for Dentine Discoloration of Silver Diamino Fluoride Associated With Potassium Iodide
The objective of this randomized clinical trial will be the comparison of dentine discoloration after treatment with: Silver Diamino Fluoride and Silver Diamino Fluoride associated with Potassium Iodide for caries lesions in…
- Trial name
- NCT04001959
- Testing
- Silver Diamine Fluoride with Potassium Iodide
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Dental Caries
Oral Health Assessment of Children in CP Class
Few oral exams are performed on 6-year-olds (key age for carious disease). This project aims to increase the number of oral check-ups for 6-year-olds in fragile areas (REP/REP+ areas).
- Trial name
- NCT04795258
- Where
- France
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
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