Clinical trials: Tooth Caries
Dental Caries
Evaluation of Antimicrobial Efficacy of Green Tea, Garlic With Lime, Pomegranate Extract and Chlorhexidine Mouth Rinses in a Group of Egyptian Children (In-Vivo Study)
the aim of the clinical trial is to evaluate the antimicrobial efficacy of the herbal mouth rinses against chlorhexidine mouth rinse.
- Trial name
- NCT05841589
- Testing
- Green tea extract mouth rinse, Garlic with lime extract mouth rinse, Pomegranate extract mouth rinse
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- omnia sayed
Child Behavior, Dental Caries
Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment
Randomised clinical trial to test the efficacy, safety and cost-effectiveness of sedatives; masked, controlled, parallel design with three arms, phase 4.
- Trial name
- NASO (NCT02447289)
- Testing
- Intranasal ketamine, Oral ketamine, Intranasal midazolam
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Dental Caries
High-strength Glass-ionomer Dental Restorations
The purpose of this study is to extend our knowledge concerning the clinical performance of two dental filling materials in molars. The study will compare two high-strength glass-ionomer filling materials.
- Trial name
- ROCK (NCT01523613)
- Testing
- Chemfil ROCK Glassionomer restoration, Fuji IX GP Extra Glassionomer restoration
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Mathilde Peters, DMD, PhD
Dental Caries
Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant
This study will evaluate effectiveness of a urethane dimethacrylate (UDMA)-quaternary ammonium methacrylate (K18) resin (UDMA-K18) smooth surface sealant to prevent biofilm attachment to tooth surfaces thereby eliminating the…
- Trial name
- K18 (NCT03306433)
- Testing
- UDMA-K18 smooth surface sealant
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dental Caries
Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries
The goal of this clinical trial is to learn if polymer-induced liquid precursor (PILP) can be used safely to treat dentin caries (cavities) in adults.
- Trial name
- NCT06727110
- Testing
- PILP Cement, PILP Conditioner
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Diagnosis, Oral, Periodontal Diseases
Study of Oral Conditions in Indigenous Populations in the State of Roraima - Brazil
The objective of this cross - sectional observational study will be to evaluate the oral conditions of indigenous people in the state of Roraima, comparing habits and hygiene conditions in each ethnicity evaluated.
- Conditions
- Diagnosis, Oral, Periodontal Diseases, Caries, Dental
- Trial name
- NCT03660410
- Testing
- Anamnesis, Oral clinical examination
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade Metropolitana de Santos
Gingivitis
Cervical Carious Lesions Restored With Calcium Silicate Based Cement (Biodentine) Compared With Glass-ionomer Cement
This study will test if applying calcium silicate cements (Biodentine) to restore cervical carious lesions might adversely affect the gingival health in comparison with conventionally used tooth colored material (GIC)
- Trial name
- NCT03418246
- Testing
- GIC, Biodentine
- Volunteers
- 28 people
- Sponsor
- Jordan University of Science and Technology
Tooth Decay
The Proximal Contact Tightness and Location in Class II Composite Restorations
This study aims to investigate consecutive biological changes in proximal contact tightness using digital force gauge and evaluate proximal contact location using cone beam computed tomography between class II direct composite…
- Trial name
- NCT05749640
- Testing
- Precontoured sectional matrix EZ COAT, PerForm™, AdDent Trimax™
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- karim mohamed
Dental Caries
Comparison of Two GIC's in the Restoration of Posterior Class II Lesions in the Primary Dentition
This study will investigate the clinical performance of a novel restorative glass ionomer (DeltaFil, DMG) in comparison to an established restorative glass ionomer (Riva Self Cure HV, SDI) in the restoration of Class II cavities…
- Trial name
- NCT05965297
- Testing
- DeltaFil, Riva Self Cure HV
- Where
- 2 sites in Brazil, Portugal
- Volunteers
- 140 people
- Sponsor
- DMG Dental Material Gesellschaft mbH
HIV Infections
A Study to Evaluate of the Efficacy of Enfuvirtide During the Induction Phase of Therapy
We hypothesize that using a potent antiretroviral such as Enfuvirtide during the induction phase of HAART therapy will lead to faster clearance of virus and infected cells, and lower number of minority variant HIV-1 strains.
- Trial name
- NCT00344760
- Testing
- Enfuvirtide, Efavirenz, lamivudine, and tenofovir
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Maryland, Baltimore
Evaluations, Diagnostic Self, Antimicrobial
ZnO Nanoparticles Coated Orthodontic Molar Tube
Orthodontic treatment is an elective procedure to improve the patient's dentofacial appearance. The complex design of fixed appliances provides a platform that leads to increased plaque accumulation around orthodontic brackets.
- Conditions
- Evaluations, Diagnostic Self, Antimicrobial, Orthodontic Appliance Complication, Bacterial Overgrowth
- Trial name
- ZnONPs (NCT06089720)
- Testing
- Zinc oxide nanoparticle coated orthodontic molar tubes (experimental), orthodontic molar tubes (control)
- Where
- Iraq
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Caries in Children
Experimental Research on Deep Carious Lesion Treatment of Molars
Maintaining dental pulp vitality is crucial for tooth preservation and functionality. Untreated dental caries may lead to pulp necrosis and infection, affecting children's growth and well-being.
- Trial name
- VITAPULP (NCT03626740)
- Testing
- TheraCal, MTA
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Dental Caries in Primary Teeth, Full-Coverage Restorations in Pediatric Dentistry
CLINICAL PERFORMANCE OF PEDIATRIC CROWNS IN PRIMARY MOLAR
The aim of this study is to compare the clinical success of three different types of prefabricated crowns commonly used in primary molar teeth: nanohybrid composite crowns, zirconia crowns, and stainless steel crowns.
- Trial name
- NCT07426445
- Testing
- Prefabricated Zirconia Crown, Prefabricated Nanohybrid Composite Crown
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Izmir Katip Celebi University
Dental Caries, Oral Microbial Colonization
Maternal Consumption of Xylitol to Reduce Early Childhood Decay (MaXED Study)
The purpose of this study is to determine if the Childsmile programme (www.child-smile.org) with the additional maternal use of xylitol is more effective at reducing dental decay in children than a Childsmile program alone.
- Trial name
- MaXED (NCT01038479)
- Testing
- Xylitol consumption, Childsmile preventative programme
- Where
- United Kingdom
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- NHS Fife
Carious Cervical Lesions
Self-Cure vs. Highly Filled Flowable Composite in Carious Cervical Lesions: 18-Month RCT
The aim of the study is to compare and evaluate the clinical performance of a self cure composite system versus a highly filled flowable composite in the restoration of carious cervical lesions over an 18 months follow up period.
- Trial name
- NCT07576673
- Testing
- Class V Restoration - Polofil, Class V Restoration - Stela
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Dental Caries
Effect of Curodont™ Repair in Patients With Early Approximal Carious Lesions
The purpose of this study is to evaluate the therapeutic benefit of Curodont Repair for the treatment of early approximal carious lesions compared to fluoride.
- Trial name
- NCT02101255
- Testing
- Curodont Repair, Fluoride
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Credentis AG
Dental Caries
Evaluation of Prefabricated CAD/CAM PEEK Crowns Used in Primary Molars
Fifty healthy cooperative children will be randomly allocated to two groups. Group I (test group) will receive CAD/CAM PEEK crowns, while group II (control group) will receive SSC.
- Trial name
- NCT06583759
- Testing
- Full coverage Crowns
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Dental Caries, Dental Restoration Failure
Clinical Performance of Posterior Composite Tooth Fillings in Adults
The purpose of this study is to determine whether a new tooth-colored composite material is effective for load-bearing dental fillings.
- Trial name
- NCT03175627
- Testing
- Filtek One, Filtek Z250
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Dental Caries in Children
Efficacy of Silver Diamine Fluoride and Its Parental Perception
This randomized clinical trial aims to compare the effectiveness of two topical fluoride application protocols, namely 38% silver diamine fluoride and sodium fluoride with added casein phosphopeptide-amorphous calcium phosphate…
- Trial name
- NCT04213573
- Testing
- silver diamine fluoride, MI Varnish
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Caries,Dental
Fluoridated Milk and Enamel Caries in Adolescents
The goal of this trial is to investigate whether low daily doses of fluoridated milk, in addition to oral hygiene routines with fluoridated toothpaste, can prevent caries development in adolescents' teeth.
- Trial name
- NCT06684405
- Testing
- sodium sodium fluoride solution (0.75 mg for subjects aged 12 and 1.0 mg for subjects aged 13), Subjects in the control group received a daily dose of 0.5 ml sterile water to be added to 200 ml of milk.
- Where
- Sweden
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Malmö University
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