Clinical trials: Tooth Caries
Periodontitis, MEDİTERRANEAN DİET
Evaluation of Nutritional Habits, Oral Hygiene, Relationship Between Dental Caries and Periodontal Condition
The purpose of this observational study is to identify the dental and periodontal health issues, oral hygiene practices, and potential relationships between them by assessing the variables that may have an impact on them.The main…
- Trial name
- NCT06129357
- Testing
- 180 individuals who applied to the Periodontology Clinic were included in the study. Individuals were divided into 3 groups as healthy (n=60), gingivitis (n=60) and periodontitis (n=60).
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Necmettin Erbakan University
Dental Caries
Caries Removal in Primary Teeth Using Er:YAG Laser
Objective: To assess and compare the 2940 nm erbium:yttrium-aluminum-garnet (Er:YAG) laser versus a conventional rotary treatment during cavity preparation in children with regard to anxiety level, pain perception, restoration…
- Trial name
- NCT05913258
- Testing
- Er:YAG laser system (Doctor smile, Pluser, Italy), Master Torque high/low-speed air rotor handpiece (KaVo Dental, Charlotte, North Carolina, USA)
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries Extending Into Dentin
Comparison of Conventional Versus Conservative Caries Removal in Primary Teeth
The sample will be, at least, 90 primary molars, randomly distributed into three groups: Group 1: IPC; Group 2: SE; Group 3: SCR.
- Trial name
- Caries_removal (NCT03650647)
- Testing
- Carious dentin removal
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dental Caries, Dental Pulp Exposure
Stepwise and One Step Techniques In Deep Dentin Lesion
This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries.
- Trial name
- NCT04351048
- Testing
- Stepwise Excavation, One Step Excavation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TIJEN PAMIR
Dental Caries, Dental Plaque
Study of the Composition of Dental Plaque
This study will examine the composition of dental plaque-a naturally occurring substance that sticks to the teeth and can cause tooth decay and gum disease.
- Conditions
- Dental Caries, Dental Plaque, Periodontal Disease
- Trial name
- NCT00001726
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Cavities of Teeth
Esthetics of Dental Composite and Adhesive System
To compare a newly developed filling composite to a current filling composite system. Two restorations will be placed in each subject, one using system A and one using system B.
- Trial name
- NCT03716349
- Testing
- Pulp vitality testing, Photos, local and/or topical anesthetic
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Erica Teixeira
Dental Pulp Capping, Dental Caries Extending to Pulp
Long-term Evaluation of Direct Pulp Capping
Calcium hydroxide and mineral trioxide aggregate have been used in vital pulp therapy with variable outcomes recorded by different study.
- Trial name
- NCT03403985
- Testing
- Calcium Hydroxide (Ca(OH)2), Mineral Trioxide Aggregate
- Where
- Jordan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pulpitis, Pain Management
Effects of Topical Anesthesia Approaches on Dental Pain During and After Restorative Management of Dental Caries
The purpose of the Research Study and Overview of Participation: This study will compare different approaches used to prevent pain when giving local anesthesia to numb the teeth while managing dental cavities and decay.
- Trial name
- NCT07379515
- Testing
- Photobiomodulation (PBM)-induced analgesia device using multi-wavelength LED, Medicated analgesia
- Volunteers
- 204 people
- Sponsor
- Dubai Health
Composite Resin, Dental Caries in Children
Nano-Hybrid vs Bulk-Fill Resin Composites
The aim of this study is to compare the 2-year clinical performance of bulk-fill composites, which can be applied as a single layer, and the nano-hybrid filled composite resins, which are frequently used in clinical routine, in…
- Trial name
- NCT05432258
- Testing
- Bulk-fill composite resin, Nano-fill composite resin
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Dental Caries
DPBRN Prevalence of Questionable Occlusal Caries Lesions
The purpose of this study was to investigate the process involved when making decisions about the diagnosis and treatment of questionable lesions, as well as determine if there is any association between lesions progression (or…
- Trial name
- NCT01201447
- Where
- 7 sites in United States, Denmark
- Volunteers
- 2,624 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Caries Class II
Clinical Performance of Injection-Molding Vs. Incremental Packing of Resin Composite in Cavitated Posterior Teeth
The clinical performance of 2 bonding and composite packing techniques in the proximal cavities of permanent posterior teeth will be assessed.
- Trial name
- NCT05020093
- Testing
- Injection molding, Incremental packing
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries
Technique for Localization of Caries Associated Bacteria on Tooth Surfaces.
There is a simple laboratory technique for localization of caries associated bacteria on tooth surfaces by taking an impression of the teeth with a material containing sucrose.
- Trial name
- NCT00421577
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Disorders Hard Tissues of Teeth, Dental Diseases
Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns
This investigation will be a randomized, prospective, longitudinal clinical trial to study the clinical performance of a new monolithic, zirconia material with shade, translucency and material graduation for chairside CAD/CAM…
- Trial name
- NCT06173167
- Testing
- Crowns self-adhesively luted, Crowns conventionally cemented
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
Dental Caries
Clinical Performance and Wear Resistance of Highly Translucent Nano Zirconia Reinforced Glass Ionomer Filling Versus Conventional Resin Composite Restorations in Patients With Proximal Carious Teeth. (A One-year Randomized Clinical Trial).
This randomized clinical study aims to evaluate the clinical performance and occlusal wear resistance of nano-zirconia reinforced glass ionomer restorations in comparison to Nano-hybrid resin composite in proximal cavities.
- Trial name
- NCT05403008
- Testing
- Zirconomer improved
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
HIV Infections
A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients
The purpose of this study is to examine how the level of HIV is reduced in the blood when anti-HIV therapy is initiated. This study will also evaluate whether adding GM-CSF or IL-12 to the anti-HIV drug regimen will increase the…
- Trial name
- NCT00000896
- Testing
- Indinavir sulfate, Lamivudine/Zidovudine, Hepatitis A Vaccine (Inactivated)
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Low Caries Experience, High Caries Experience
VDR and TFIP11 Gene Polymorphism and Gene-environmental Interaction in Adults
VDR and TFIP11 Gene polymorphism and gene-environment interactions on caries etiology and susceptibility in adults.
- Trial name
- NCT04124718
- Testing
- high caries experience
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Dental Caries Class II
Evaluation of Clinical Success of Bulk Fil Composite Versus Highly Viscous Glass Ionomer in Primary Class II Molars
evaluate the clinical performance of EQUIA Forte ® ( a HVGIC) and Plafique® Bulk Flow composite resin when placed in class II cavities in primary molars.
- Trial name
- NCT06235489
- Testing
- Palfique Bulk Flow
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries, Endodontically Treated Teeth
Clinical Performance of Posterior Indirect Adhesive Restorations
Clinical performance of indirect adhesive restorations - onlays, overlays- luted with light-cured composite resin will be evaluated.
- Conditions
- Dental Caries, Endodontically Treated Teeth, Dental Restoration Failure of Marginal Integrity, Wear, Occlusal
- Trial name
- NCT04838483
- Testing
- Indirect adhesive restoration of posterior teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Okan University
Caries,Dental
Diagnostic Ability of Near Infrared Transillumination Detecting Interproximal Caries as Compared to Conventional Bitewing Radiographs
Specific Aims 1. To determine the diagnostic efficacy of CariVu and BWX for detecting interproximal carious lesions in primary dentition BWX and CariVu images will be taken in random order.
- Trial name
- NCT05362461
- Testing
- Near Infrared Transillumination
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Dental Caries
Involvement of Archaea in Carious Disease
Dental caries is a major public health probleme the result of hard tissue demineralization and oral microbiota changes. Methanogenic archaea, mainly Methanobrevibacter oralis, are associated with various oral problems, including…
- Trial name
- CARIARCHAE (NCT06787261)
- Testing
- saliva sample, carious tissue samples
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
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