Clinical trials: Tooth Caries
Class I Dental Caries
Clinical Performance and Wear Resistance of Two Nano Ceramic Resin Composite in Class I Cavities
in patients with Class I Cavities, will the use of Zenit Nano Ceramic Composite restorations have similar clinical performance to conventional Ceram-X Nano Ceramic Composite restorations, evaluation of restorations will be done…
- Trial name
- NCT04738604
- Testing
- Ceram•X (Dentsply De Trey GmbH, Konstanz, Germany, Zenit Nano Ceramic Composite (PRESIDENT DENTAL, GmbH, Munich, Germany)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Decay
Clinical Assessement of Glazed Versus Polished Lithium Disilicate Crowns in Surface Roughness and Enamel Antagonists Wear
It is believed that final glazing yields the most acceptable ceramic surfaces in terms of smoothness. However, since reglazing must be performed in a dental laboratory with the use of a thermal furnace, it requires multiple…
- Trial name
- NCT03696849
- Testing
- polished emax Press
- Volunteers
- 28 people
- Sponsor
- Cairo University
Dental Caries
Fluoride in Saliva After Use of Fluoride Toothpastes Followed by Fluoride Mouthrinses
This study will evaluate fluoride (F) bioavailability in saliva when using an over-the-counter mouthrinse of 226 ppm F, immediately after brushing with an over-the-counter toothpaste of 1,100 ppm F or a prescription toothpaste of…
- Trial name
- NCT05601154
- Testing
- Crest Cavity Protection toothpaste, Crest Cavity Protection toothpaste followed by Act Mint Fluoride Rinse, Colgate PreviDent 5000+ toothpaste
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dental Caries
Effect of aPDT on Deep Caries in Permanent Tooth
The aim of this study is to assess the clinical effect of aPDT on deep caries in permanent teeth. Half of the deep caries will receive aPDT disinfect in restorative treatment procedure, while the other half will receive sodium…
- Trial name
- NCT02929914
- Testing
- Local anesthesia and rubber dam isolation, Incomplete caries removal and microbiological samples collection, Dentin washed with sodium 0.9% saline
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fujian Medical University
Dental Caries
Effect of a Novel Sweetener on the pH of Dental Plaque.
Bacteria that live in the mouth can digest fermentable carbohydrates such as sucrose, fructose, and glucose to make acid. This acid can cause demineralization of the tooth and lead to dental caries or decay.
- Trial name
- NCT00739778
- Testing
- food - novel sweetener, food vehicle blank, food - sweetener, positive control
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cargill
Dental Caries
Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study
The study hypothesis is the difference in therapeutic effect of two varnish formulations (G1 = NaF, 2.26%F, G2 = NaF, 2.71% F + CaF2).
- Trial name
- NCT00723515
- Testing
- sodium fluoride, sodium fluoride calcium fluoride
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Pernambuco
Carious Teeth
Outcome of Full Pulpotomy Using Calcium Silicate Based Materials
Permanent teeth with carious pulp exposure and indicated for full pulpotomy will be treated using three different materials using aseptic technique and will be subsequently followed up clinically and radiographically at 6 months…
- Trial name
- pulpotomy (NCT04345263)
- Testing
- MTA pulpotomy
- Where
- 2 sites in Jordan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Reversible Pulpitis, Deep Carious Lesions
Comparative Evaluation of Calcium Silicate-doped Treated Dentin Matrix and Mineral Trioxide Aggregate as Miniature Pulpotomy Biomaterials in Deep Carious Lesions
AIM: To compare the efficacy of a Novel calcium silicate doped treated dentin matrix and Mineral Trioxide aggregate as biomaterials for miniature pulpotomy.
- Trial name
- hTDM (NCT07302438)
- Testing
- Calcium Silicate doped treated dentin matrix for miniature pulpotomy (CaSi+hTDM MP)., Mineral Trioxide Aggregate (MTA) for Miniature Pulpotomy
- Where
- 2 sites in India
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Gingival Inflammation, Dental Caries
Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences
Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's…
- Trial name
- NCT07124533
- Testing
- Toothpaste Tablet, Conventional Toothpaste
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Dental Caries
Oral Health Knowledge and Caries Experience in Adults
This cross-sectional study assessed the level of oral health knowledge and its relationship with caries experience, independently of age and sex, in adult patients attending a university dental clinic in Gran Canaria (Spain).
- Trial name
- NCT07881380
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Las Palmas de Gran Canaria
Dental Plaque, Dental Caries
Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse
This study aims to investigate the impact of a bromelain pre-rinse adjunct on oral plaque removal in orthodontic subjects. The study's null hypothesis states that there is no statistically significant difference in visual plaque…
- Trial name
- NCT04512482
- Testing
- Bromelain, Powdered sugar
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dental Caries
Caries Arresting in Primary Molar Teeth Using SDF VS ART
This study aimed to evaluate the oral health related quality of life ( OHRQoL), during caries management in children with vital carious primary teeth with no signs of irreversible pulpitis using SDF alone or SDF in combination…
- Trial name
- NCT05188846
- Testing
- SDF, SDF + ART (SMART technique )
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ola Adel Abdelfadil Ahmed
Occlusal Caries
Evaluation of Clinical Performance for Recent Non Coated Glass Ionomer in Posterior Teeth
In patients with occlusal caries in posterior teeth, does the use of recently introduced non coated glass ionomer provide better clinical performance compared to conventional glass ionomer with surface coating? -Primary…
- Trial name
- NCT04463342
- Testing
- Non Coated Glass Ionomer, Conventional Glass Ionomer with Coat
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Autistic Disorder, Dental Caries
Effectiveness of Sealants and Fluoride Varnish in Caries Prevention in Children With Autism Spectrum Disorders
The aim of the study is to compare application of sealants together with fluoride varnishes versus only fluoride varnishes in preventing caries lesions development in the occlusal surface of first permanent molars of children…
- Conditions
- Autistic Disorder, Dental Caries, Pit and Fissure Caries
- Trial name
- NCT05146479
- Testing
- Fluoride varnish and pit and fissure sealants onto first permanent molars
- Where
- Italy
- Volunteers
- 232 people
- Sponsor
- University of Milan
Tooth Diseases
Clinical Evaluation of Three Different Universal Adhesives in Non-carious Cervical Lesions
The aim of this randomized, controlled prospective clinical trial is to evaluate and compare the performances of three different universal adhesives using a flowable universal composite resin in the restoration of non-caries…
- Trial name
- NCT03415412
- Testing
- Clearfil Univesal Bond, IBond Universal, G-Premio Bond
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dentin Caries
Comparison Of Clinical And Radiological Success Of Pulpotomy Treatments Performed With Proroot MTA, NeoPUTTY MTA, TheraCal PT In Primary Teeth
The goal of this randomized clinical trial is to compare clinical and radiological success rates of NeoPutty MTA, ProRoot MTA and TheraCal PT pulpotomy in 4-10 years old healthy pediatric patients.
- Trial name
- NCT07260357
- Testing
- ProRoot MTA Pulpotomy, NeoPUTTY MTA Pulpotomy, TheraCal PT Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Caries,Dental
Clinical Trial Proximal Caries Infiltration and Detection
The purpose of this study is to investigate the clinical efficacy of resin infiltration (Icon, DMG, Germany) compared to fluoride varnish (Duraphat Fluoride Varnish, Colgate, USA) in the management of proximal early caries…
- Trial name
- NCT01796106
- Testing
- Resin infiltration, Fluoride varnish & Oral hygiene instruction
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dental Caries in Children
Multi-Media Parent-based Intervention to Promote Dental Hygiene Among Young Children: BeReady2Smile
This application, BeReady2Smile, will promote dental health behavioral parenting strategies among parents by incorporating a behavioral program for their children.
- Trial name
- BR2S (NCT03637309)
- Testing
- BeReady2Smile Video and App
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Dental Caries
Effect of Educational Intervention in Mothers for Prevention of Caries in Their Children
The purpose of this study is to determine the effect of an educational intervention on mothers knowledge, attitudes and practices for preventing childhood caries.
- Trial name
- NCT01763138
- Testing
- oral health education, reminder phone call
- Where
- Pakistan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
Periodontal Diseases, Inflammation Gum
Evaluation of Oral Condition and the Effect of Dental Treatment on Physical Parameters of Athletes
It is essential that athletes have perfect general health. Oral health plays an important role in this healthy framework necessary so that the results that must be achieved by athletes are not influenced.
- Conditions
- Periodontal Diseases, Inflammation Gum, Caries,Dental
- Trial name
- NCT04251858
- Testing
- Dental Scaling, Oral hygiene instruction
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidade Metropolitana de Santos
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