Clinical trials: Tooth Caries
Dental Decay
Effect of Therapeutic Measures in Dental Caries Reduction in Children With Primary Dentition From Medellín City
The propouse of this study is to evaluate some combined preventive measures, of easy application in children under 6 years old as education, brush teeth, fluoride free tooth paste,fluoridated tooth paste, professional cleaning…
- Trial name
- NCT00475618
- Testing
- topical fluoride varnish application., professional cleaning, No fluoride toothpaste
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CES University
Dental Caries, Insufficient Dental Filling
A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy in Deciduous Teeth
The overall aim of this clinical investigation is to assess the clinical performance and safety of composite restorations cured with fast curing mode (5 seconds with 2000 mW/cm²) in primary molars.
- Trial name
- NCT07212660
- Testing
- Fast curing mode, Conventional curing mode
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
Dental Caries
LT Comparative Effectiveness of 2 Caries Treatments
This study is a continuation of a cluster randomized clinical trial (cRCT) conducted in 33 publicly subsidized housing facilities/sites (HUD Section 202) and other low-income housing voucher programs in NE Ohio.
- Trial name
- NCT07213661
- Testing
- A "simple medical strategy" consisting of silver diamine fluoride (SDF), A "typical dental strategy" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride Varnish (FV)
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Caries,Dental
Fluoridated Milk and Enamel Caries in Adolescents
The goal of this trial is to investigate whether low daily doses of fluoridated milk, in addition to oral hygiene routines with fluoridated toothpaste, can prevent caries development in adolescents' teeth.
- Trial name
- NCT06684405
- Testing
- sodium sodium fluoride solution (0.75 mg for subjects aged 12 and 1.0 mg for subjects aged 13), Subjects in the control group received a daily dose of 0.5 ml sterile water to be added to 200 ml of milk.
- Where
- Sweden
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Malmö University
Deep Caries
Pre-operative Radiograph of Deep Carious Lesions as a Predictive Tool for Pulpal Exposure
Preserving pulpal vitality is a major challenge when excavating deep caries lesions without severe symptomatology. Pulpal exposure alters success of the treatment (dropping from 93% for indirect pulp treatment with selective…
- Trial name
- R2 (NCT04607395)
- Testing
- pre-operative radiograph
- Where
- France
- Volunteers
- 358 people
- Sponsor
- Hospices Civils de Lyon
Caries, Dental, Health Behavior
Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children
This is a randomized clinical trial to test the efficacy of a parent-targeted text message-based intervention program on caries incidence and oral health behaviors (child and parent).
- Trial name
- iSmile (NCT03294590)
- Testing
- OHT Parent targeted text messages, CWT Parent targeted text messages
- Where
- United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Boston University
Dental White Spots, Dental Caries
MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study
The objective of this clinical study is to evaluate the efficacy of multiple applications of MI Varnish in combination with MI Paste Plus in caries protection and remineralization in comparison to the use of a control (Crest…
- Trial name
- GC-WS (NCT02424097)
- Testing
- CPP-ACP 5% sodium fluoride varnish & 900ppm fluoride paste, 1,100pm F-toothpaste and 0.5%NaF rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries
The Use of Pit and Fissure Sealants in Children Requiring Caries Related Dental Extractions
The purpose of thus study is to assess the feasibility and inform the planning of a proposed definitive randomised controlled clinical trial to investigate the efficacy of sealing permanent molars in children requiring caries…
- Trial name
- NCT02443896
- Testing
- Pit and Fissure Sealant of permanent molars, No sealant of permanent molars
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Birmingham
Dental Caries
Giomer vs Glass Ionomer Cement for ART Occlusoproximal Restorations: a Randomized Clinical Trial
Although the Atraumatic Restorative Treatment (ART) is well settled in the literature regarding occlusal-proximal cavities, the longevity of these restorations is still lower when compared to occlusal ones.
- Trial name
- NCT02962713
- Testing
- ART with Equia, ART with Giomer Beautifil-Bulk Restorative
- Where
- Brazil
- Volunteers
- 182 people
- Sponsor
- University of Sao Paulo
Caries, Dental, Cariostatic Agents
Reducing Bacteria That Cause Tooth Decay
The purpose of the study is to determine the effect of a two-step mouth rinsing procedure on reducing the germs (mutans Streptococci) that cause tooth decay.
- Trial name
- NCT03062605
- Testing
- Iodine (Betadine), NaOCL
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Rheumatic Heart Disease, Pregnancy
Dental Anesthesia in Pregnant Women With Rheumatic Heart Disease
The hemodynamic parameters of 31 pregnant women with rheumatic valve disease, undergoing restorative dentistry under local anesthesia with 2% solution of lidocaine, divided in two groups, with (Group LE) and without 1:100,000…
- Conditions
- Rheumatic Heart Disease, Pregnancy, Dental Caries
- Trial name
- NCT00482573
- Testing
- Dental local anesthesia
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Sao Paulo
Dental Caries, Restorative Material
Evaluate the Effectiveness of an Experimental Urethane Dimethacrylate Resin Based Dental Composite Material
This double blind randomized controlled prospective clinical trial will compare the clinical success of two tooth colored resin composite dental filling materials - TPH3 (Dentsply Caulk) and an experimental urethane…
- Trial name
- NCT02018822
- Testing
- urethane dimethacrylate, TPH3, Esthet-X HD
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Dental Caries
ETT Rotation During Nasal Fiberoptic Intubation
A nasal endotracheal tube (ETT) is routinely placed in children and a fiberoptic scope (FOS) is commonly used for this purpose. Resistance to the passage of ETT is frequently encountered as it is advanced over the FOS for…
- Trial name
- NCT02405546
- Testing
- Pre-Rotated (Group R), No pre-rotation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Extremely Deep Caries, Pulpitis
Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries
Recent clinical trials comparing pulpotomy versus root canal treatment (RCT) have shown promising outcomes; however, the current evidence lacks generalisability to general practitioners.
- Trial name
- NCT07242742
- Testing
- Full Pulpotomy, root canal treatment and intracanal medicament
- Where
- Singapore
- Volunteers
- 93 people
- Sponsor
- National University Hospital, Singapore
Dental Caries
Reliability of Fluorescent Camera and Caries Detection Dye Versus the Visual Tactile Method
1. Three dentinal carious lesions will be chosen in this study and will be in the same patient. 2. Using local anaesthesia and rubber dam, the operative field will disinfected with 1% hypochlorite, and the dentine lesions should…
- Trial name
- NCT03051594
- Testing
- fluorescent camera, caries detector dye, visual tactile assessment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Effectiveness of ICCMS in Reducing the Incidence of Dental Caries in Children
The aim of the present study is to evaluate the effectiveness of using the ICCMS (International Caries Classification And Management System)in reducing caries lesions incidence compared to a control group that use different…
- Trial name
- NCT03488056
- Testing
- ICCMS, SESC standard care
- Where
- Brazil
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pulpitis - Irreversible, Caries
Endodontic-Restorative Pre-Radiation Therapy of Head and Neck Cancer Patients
Pilot study involving 20 patients undergoing dental treatment prior to radiation therapy. Comparison of outcome parameters to existing data of age and gender matched patients.
- Conditions
- Pulpitis - Irreversible, Caries, Head and Neck Cancer
- Trial name
- EndoRest (NCT04996641)
- Testing
- Root canal treatment and crown
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Oral Health, Dental Caries
Improved Oral Health and Dental Care in Children with Congenital Heart Disease
Background: Congenital heart disease (CHD) is one of the most common congenital anomalies in children. As the risk for endocarditis following bacteraemia is more common during daily oral hygiene routines, such as tooth brushing…
- Trial name
- ORALPEDHEART (NCT03329170)
- Testing
- educational intervention using motivational interviewing
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- My Blomqvist
White Spot Lesion, Caries
Clinical Effectiveness of Various Professionally Applied Fluoride Prophylaxes in Groups at High Risk
The study is to compare the prophylactic and therapeutic clinical effectiveness of two fluoride varnishes in children at high caries risk.
- Trial name
- NCT02027922
- Testing
- Fluor Protector S
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Medical University of Warsaw
Low Back Pain
Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain
The goal of this proposal is to test the overall hypothesis that subjects with chronic or recurrent low back pain have an abnormal soft tissue response to acupuncture needling, and that this altered response is associated with…
- Trial name
- NCT00487266
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
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