Clinical trials: Tooth Demineralization
Dental Caries, Oral Bacterial Infection
Ecological Effect of Arginine Dentifrice on Oral Microbiota
caries-free (CF) individuals caries-active (CA) individuals (DMFT ≥ 6) will be recruited. Subjects will be instructed to brush their teeth twice daily for 3 min using Colgate® Sensitive Pro-Relief® toothpaste (containing 8%…
- Conditions
- Dental Caries, Oral Bacterial Infection, Microbiota
- Trial name
- NCT02988349
- Testing
- Colgate® Sensitive Pro-Relief® toothpaste
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sichuan University
Periodontitis, Dental Caries
Immediate Implant Placement in the Molar Regions
The purpose of this study is to look at the bonehealing when a molar has been extracted and immediately replaced by an implant leaving some defects around the implant.
- Conditions
- Periodontitis, Dental Caries, Periapical Periodontitis
- Trial name
- NCT00226148
- Testing
- Use of a membrane to cover bonedefects around implant, Use of bonechips to fill up defects around implant, Use of membrane and bonechips to manage defects
- Where
- Denmark
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Carious Teeth
Clinical Performance of One-shade Universal Dental Resin Composite as Posterior Restoration
This study is aimed to evaluate the clinical performance of new One-shade universal composite resin as posterior restoration using US Public Health Service "USPSH" criteria for color match, marginal adaptation, surface texture…
- Trial name
- NCT05500547
- Testing
- US Public Health Service "USPSH" criteria for assessment of success of resin composite restorations
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Dental Caries, Dental Plaque
The Effect of Arginine on Biofilm Composition, Architecture and Metabolism
Arginine is an adjunct to oral health care that has the potential to modulate the composition and activity of the microbial community of dental biofilms towards a health-related status without harmful effects for the resident…
- Conditions
- Dental Caries, Dental Plaque, Microbial Colonization
- Trial name
- NCT06135792
- Testing
- Arginine
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Caries, Dental
Anterior Zirconia vs. Resin Strip Crowns
This study is comparing the effectiveness of two different dental crown fillings (resin crowns and zirconia crowns) for primary front teeth (incisors).
- Trial name
- NCT03889535
- Testing
- Resin strip crowns, Zirconia crowns
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- The Hospital for Sick Children
Dental Caries, Denture, Partial, Removable
Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite
Nobio has developed dental restorative materials with long term antibacterial properties in order to fight recurrent decay/caries around restorations.
- Trial name
- Nobio (NCT04059250)
- Testing
- Nobio composite, traditional composite
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries
Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth
Evidence that the data flow analysis tests, there are still no studies that show the clarity of the protocols of its application, including the interval and execution factors of applications, concentration of fluoridation and…
- Trial name
- CEPECO3 (NCT03827889)
- Testing
- WMP of fluoride varnish, TWLP of fluoride varnish, DHP (educational intervention)
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Universidade Ibirapuera
Dental Caries
Probiotics That Moderate pH and Antagonize Pathogens to Promote Oral Health
This study will examine the mechanisms of action of probiotics and synbiotics for control of oral diseases, with a particular focus on exploring new strategies for caries prevention and treatment.
- Trial name
- NCT02999230
- Testing
- Caries Free 1.5% Arginine, Caries Active 1.5% Arginine
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Florida
Dental Caries
A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model
An in situ model will be used to evaluate and compare enamel remineralization of human enamel specimens after single use of experimental children's toothpastes.
- Trial name
- NCT01607411
- Testing
- Fluoride
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tooth Erosion
In Vivo Quantification of Dental Demineralisation Using OCT With and Without Esomeprazole
Dental erosions in 30 male and female patients with proven abnormal gastrooesophageal reflux will be assessed clinically and using a novel optical coherence tomography (OCT) laser technique before and after double-blind…
- Trial name
- NCT00564330
- Testing
- Esomeprazole
- Volunteers
- 30 people
- Sponsor
- Brain-Gut Research Group
Dental Restoration, Dental Caries
Resin Bulkfill Dual-Cured of Proximal Restoration. Clinical Trial
Objective: To evaluate the immediate clinical performance using FDI criteria in occlusal and proximal lesions restored with dual polymerization bulkfill composite resin.
- Trial name
- NCT05013853
- Testing
- Restoration teeth
- Where
- Chile
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Andres Bello
Tooth Decay, Cavities of Teeth
Plaque Removal Effectiveness of a Flossing Device Compared to the Conventional Flossing in Adults
Objective: To evaluate the effectiveness in plaque removal of the new device; Dental floss holders and compare the results to the conventional way of flossing.
- Conditions
- Tooth Decay, Cavities of Teeth, Gingivitis, Plaque
- Trial name
- NCT06318819
- Testing
- Dental Floss Holders
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maha A. Bahammam
Children in School
Caries Risk Assessment in Children and Adolescents in the Alpes Maritimes (France)
Identification of caries high risk subjects. Studying the relevance and the distribution of caries risk factors as defined by the HAS, and the part played by the zone of schooling (priority education area or not) Studying the…
- Trial name
- NCT01372436
- Where
- 2 sites in France
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Dental Caries
Reliability of Fluorescent Camera and Caries Detection Dye Versus the Visual Tactile Method
1. Three dentinal carious lesions will be chosen in this study and will be in the same patient. 2. Using local anaesthesia and rubber dam, the operative field will disinfected with 1% hypochlorite, and the dentine lesions should…
- Trial name
- NCT03051594
- Testing
- fluorescent camera, caries detector dye, visual tactile assessment
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Clinical Evaluation of Direct and Indirect Composites
The most commonly used materials in the treatment of decayed teeth are amalgam and composite resins. Because amalgam cannot meet the aesthetic expectations of patients and the rapidly increasing belief that it is toxic, its use…
- Trial name
- NCT06667271
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Dental Caries
Preventive Effect of a Probiotic Tablet on Oral Health in Preschool Children
The aim of the prospective project is to investigate effect of daily probiotic supplements on dental caries development in preschool children living in a low socioeconomic immigrant area in souithern Sweden.
- Trial name
- NCT01720771
- Testing
- probiotic tablet, sugar pill
- Where
- Sweden
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
Educational Intervention in Preventing Early Childhood Caries
Objective: The aim of this study is to assess the effectiveness of an oral health educative intervention in preventing early childhood caries (ECC).
- Trial name
- NCT01502566
- Testing
- Education Intervention
- Where
- Brazil
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Carious Lesion
Clinical Evaluation of SDF Combined With KI Versus SDF in Management of Class I Carious Lesions
To evaluate the clinical performance of High-Viscosity Glass Ionomer (EQUIA) versus Silver Diamine Fluoride combined with Potassium Iodide (Riva Star) and Sliver Diamine Fluoride (SDF) under High-Viscosity Glass Ionomer (EQUIA)…
- Trial name
- NCT05485272
- Testing
- Silver Diamine Fluoride combined with Potassium Iodide., Silver Diamine Fluoride., High-Viscosity Glass Ionomer.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Radiographic Contrast To Differentiate Cavitated From Non-cavitated Tooth Decay
The proposed test is intended to enable dentists to differentiate between cavitated and non-cavitated tooth decay in the areas where teeth are in contact (interproximal surfaces).
- Trial name
- NCT02359279
- Testing
- Sodium iodide
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
Dental Caries, Early Childhood Caries
Cohort Zero Caries
The purpose of this study is to compare the effectiveness of a traditional oral health educational program and a program based on the theories of the Motivational Interview directed to the child's mothers/fathers/responsible…
- Trial name
- CZC (NCT02578966)
- Testing
- Motivational Interview, Traditional health education
- Volunteers
- 650 people
- Sponsor
- Hospital Nossa Senhora da Conceicao