Clinical trials: Tooth Demineralization
Dental Caries
Microbiological Evaluation and Clinical 24-month Follow-up of Adhesive Systems on Carious Dentin
The objectives were to evaluate the antibacterial effect of self-etching adhesives on carious dentin and the clinical results of restorations in a randomized controlled clinical trial.
- Trial name
- NCT05676671
- Testing
- Applications of self-etching adhesives and dental restorations
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Anxiety, Dental Fear
Dental Anxiety in Children Attending Emergency Versus Routine Dental Care
The goal of this observational study is to learn whether children who come to a pediatric dental emergency clinic have higher dental anxiety than children who come for routine dental care.
- Trial name
- NCT07882914
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Caries
Evaluation Of Clinical Performance of Self-adhering Flowable Composite vs Conventional Flowable Composite in Cervical Carious Lesions
This clinical trial will be conducted to compare the clinical performance of a new self-adhering flowable composite in restoring CLs compared to conventional flowable composite in geriatric patients over 12 months.
- Trial name
- NCT04475172
- Testing
- Self-Adhesive Flowable Composite
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Reversible Pulpitis, Dental Caries
Effect of Hemostatic Agents on TheraCal PT Pulpotomy Success in Primary Molars
Dental caries in primary teeth can sometimes lead to inflammation of the dental pulp, the soft tissue inside the tooth. When the pulp remains capable of healing, pulpotomy may be performed to preserve the tooth until its natural…
- Conditions
- Reversible Pulpitis, Dental Caries, Primary Molar Pulpotomy, Dental Pulp Exposure
- Trial name
- CEHA-TP RCT (NCT07876934)
- Testing
- 2.5% Sodium Hypochlorite applied to pulpal tissue/stumps for 3 minutes to achieve hemostasis prior to TheraCal PT placement during primary molar pulpotomy and 15% Ferric Sulfate (Astringedent™ 15.5%)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Reem Mohamed Gaber
Cardiac Disease, Dental Caries
Saliva Profiles in Children With Congenital Heart Disease
The purpose of this study was to evaluate whether there are relationships between the salivary oxidative stress status of children with CHD directly dental caries including gender, age, salivary flow rate, salivary pH, salivary…
- Trial name
- NCT03457974
- Testing
- saliva
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dental Caries, Crowned Posterior Teeth
Hall Technique vs Conventional Technique in Permanent Teeth
The purpose of this study is to evaluate and compare the clinical and radiological performance of stainless steel crowns using conventional and Hall technique on permanent molars
- Trial name
- NCT07100028
- Testing
- SSC crown with Hall technique, SSC with conventional technique
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries in Children, Tooth Diseases
Hall Technique or Modified Hall Technique of Deep Carious Lesions in Primary Molars
The purpose of this randomized clinical trial is to compare the clinical/radiographic success of Hall technique and modified Hall technique in the treatment of primary molars with deep dentine carious lesions in children…
- Conditions
- Dental Caries in Children, Tooth Diseases, Tooth Demineralization, Stomatognathic Diseases
- Trial name
- NCT05220865
- Testing
- Hall Technique, Modified Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Caries,Dental
Clinical Performance of Injectable Composite Resins in Class I Cavities
Purpose of research: Evaluation and comparison of 24-month clinical performance of injectable and conventional resin composites in class I cavities.
- Trial name
- NCT06192667
- Testing
- GC Geanial Injectable (Tokyo,Japan), 3M Filtek Z250 Universal Restorative (Germany)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Cost-efficacy of Atraumatic Restorations (ART) Using Different Encapsulated Glass Ionomer Cement
Given the clinical damage caused by errors commonly made during the dosage and handling of glass ionomer cement (GIC) of high viscosity powder-liquid type, the use of encapsulated ionomer has been recommended for final…
- Trial name
- NCT02730000
- Testing
- ART with Equia, ART with Riva Self Cure
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- University of Sao Paulo
Dental Caries
Knowledge, Attitude and Practice of a Group of Egyptian Dental Interns Toward Caries Risk Assessment
Scientific background(Statement of the problem): Dental caries is a disease that occurs through complex interaction of four major factors: the host, acidogenic bacteria, fermentable carbohydrates and time.
- Trial name
- NCT03609034
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Appliance Complication, Dental Caries
Effect of Chlorhexidine Gel on Bacterial Count During Fixed Orthodontic Treatment
This study investigates the benefit of using chlorhexidine gel as an antimicrobial agent in orthodontic patient to reduce caries risk and the possible consequential effect of this use on the orthodontic brackets used for the…
- Trial name
- NCT02001311
- Testing
- Chlorhexidine gluconate
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries, Primary Teeth
Discomfort Evaluation During Atraumatic Restorative Treatment in Children
This study evaluates the patient 's discomfort when submitted to partial caries removal through the atraumatic restorative treatment compared to chemo-mechanical caries removal using Papacarie™ gel.
- Conditions
- Dental Caries, Primary Teeth, Post Dental Restoration
- Trial name
- NCT03143387
- Testing
- Caries removal using only manual instruments, Caries removal using Papacarie gel
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Caries,Dental, Crown of Tooth With Poor Contour
Clinical and Radiographical Evaluation of CAD-CAM Crowns With and Without Deep Margin Elevation
Deep margin elevation (DME) is a non-invasive restorative technique to relocate the deep cervical margin to a supragingival position using resin composite.
- Conditions
- Caries,Dental, Crown of Tooth With Poor Contour, Broken Teeth, Survival, Prosthesis
- Trial name
- NCT06114030
- Testing
- Deep margin elevation with composite resin and Lithium disilicate glass-ceramic crowns
- Where
- United Arab Emirates
- Volunteers
- 560 people
- Sponsor
- University of Sharjah
Dental Caries, Gingivitis
Parental Perception of Oral Health-Related Quality of Life in Sudanese Refugee vs. Egyptian Children
This cross-sectional analytical study aims to assess and compare parental perceptions of oral health-related quality of life (OHRQoL) among Sudanese refugee children and Egyptian children aged 6-12 years living in Egypt.
- Conditions
- Dental Caries, Gingivitis, Oral Health, Refugee Health
- Trial name
- NCT07011381
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Teeth; Lesion, Dental Root Caries
5-year Clinical Evaluation of Cavity Lining on the Restoration
The purpose of this double-blind, randomized trial is to compare the clinical performance of a composite restorations in root surface carious lesions with or without resin modified glass ionomer lining.
- Trial name
- NCT03802539
- Testing
- Glass Liner
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Comparing Stainless Steel Crowns With Prefabricated Resin Crowns in Primary Molar Teeth
The main reason for this research study is to learn more about a new flexible white dental crown (BioFLX) by comparing it to an existing flexible metal crown (Stainless Steel Crown).
- Trial name
- NCT06713330
- Testing
- BioFLX crown, 3M Stainless Steel Crown
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Dental Erosion
Effect of Smoking on Saliva Composition and the Development of Dental Erosion
The aim of this study is to investigate whether smoking is associated with changes in salivary composition and/or predisposition to erosion.
- Trial name
- NCT04208802
- Testing
- Use of fluoridated toothpaste, Wearing of an intraoral device with bovine tooth samples, Wearing of an intraoral device with resin samples
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Dental Caries, Dental Caries Class II
Clinical Performance of Novel Alkasite Restorative Material "Cention Forte" in Class II Restorations
Background \& Rationale: Self-adhesive materials eliminate the need for adhesive protocols, offering advantages for direct restorations. The bulk-fill technique simplifies application by allowing a single-layer restoration.
- Trial name
- NCT06833528
- Testing
- tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries, Artificial Intellegence
Accuracy of an Artificial Intelligence-assisted Diagnostic System for Caries Diagnosis: a Prospective Multicenter Clinical Study
This clinical trial was designed as a prospective, multicenter, multi-reader multi-case (MRMC), superiority, parallel-controlled study. Participants who met the trial criteria and signed the informed consent form were enrolled.
- Conditions
- Dental Caries, Artificial Intellegence, Diagnosis, Machine Learning
- Trial name
- NCT06428344
- Volunteers
- 220 people
- Sponsor
- Zhejiang Provincial People's Hospital
Obesity, Obesity, Childhood
Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-study
Objectives To compare oral health (dental caries, periodontal status, and erosive tooth wear (ETW)), diet and oral hygiene habits between obese and normal weight adolescents, and to explore possible risk associations.
- Conditions
- Obesity, Obesity, Childhood, Tooth Wear, Tooth Erosion
- Trial name
- NCT05146557
- Testing
- Dental examination
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University Ghent