Clinical trials: Tooth Discoloration
Dentin Hypersensitivity, Tooth Discoloration
Management of Dentinal Hypersensitivity Using Two Dentifrice Technologies
This study evaluates the effectiveness of Scigates foam mouth sanitizer 2 in 1 toothpaste and mouthwash in reducing tooth sensitivity and improving tooth whitening compared to Lacalut® White \& Repair toothpaste.
- Trial name
- NCT07511530
- Testing
- Scigates Foam Mouth Sanitizer 2 in 1 Toothpaste and Mouthwash, Lacalut White and Repair Toothpaste
- Where
- Jordan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Prof. Mayyas Al-Remawi
Molar Incisor Hypomineralisation, Enamel Hypomineralization
Comparison of Two Minimally Invasive Approaches for Masking Molar-Incisor Hypomineralization Opacities
This clinical study aimed to compare the effectiveness of two minimally invasive approaches for masking molar-incisor hypomineralization (MIH) opacities and to evaluate esthetic perceptions of children and their parents.
- Conditions
- Molar Incisor Hypomineralisation, Enamel Hypomineralization, Tooth Discoloration
- Trial name
- NCT07494682
- Testing
- Resin infiltration, Etch Bleach Seal Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Tooth Discoloration
Efficacy of Manual Toothbrushes in Removing Tooth Stains
Efficacy of Manual Toothbrushes in Removing Tooth Stains: A 6-Week Clinical Research Study.
- Trial name
- NCT06486974
- Testing
- NaF, Na MFP
- Where
- Dominican Republic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth
A Comparative Clinical Study Assessing Dentin Thickness and Discoloration in Deep Carious Lesions Treated With Biodentine Alone Versus Diode Laser Pre-treatment Followed by Biodentine
This interventional clinical study aims to compare dentin thickness preservation and tooth discoloration in deep carious lesions treated with Biodentine alone versus diode laser pre-treatment followed by Biodentine.
- Conditions
- Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth, Deep Carious Lesion
- Trial name
- NCT07358442
- Testing
- Biodentin, Diode laser
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Misr International University
Tooth Discoloration, Tooth Sensitivity
At-home Bleaching Using Clear Retainers
The aim of this project is to clinically evaluate patient satisfaction, whitening efficacy, tooth sensitivity, and gingival irritation during at-home whitening with 10% carbamide peroxide using an Essix-type retainer or a Vivera…
- Conditions
- Tooth Discoloration, Tooth Sensitivity, Gingivitis, Satisfaction, Patient
- Trial name
- NCT05835453
- Testing
- Whitening
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Tooth Discolouration
16% Carbamide Peroxide Home Bleaching: Soft vs. Rigid Tray in a Randomized Blinded Equivalence Trial
The aim of this clinical study is to evaluate patient satisfaction, bleaching efficacy, and the risk and severity of tooth sensitivity and gingival irritation during home bleaching with 16% carbamide peroxide using conventional…
- Trial name
- Rigid tray (NCT06881654)
- Testing
- Bleaching teeth
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Tooth Discoloration
A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent
The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile.
- Trial name
- NCT06782087
- Testing
- nano chitosan
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Gingivitis, Periodontal Diseases
Changes in Oral Health in Tobacco Cigarettes Smokers After Switching to Combustion-Free Nicotine Delivery Systems
Although the well-known detrimental effects of conventional cigarette smoking on oral health, there are still lack of evidences about the impact of less harmful alternatives (such as electronic cigarettes or heat not burn…
- Trial name
- SMILE (NCT04649645)
- Testing
- TOBACCO CIGARETTES, COMBUSTION-FREE NICOTINE DELIVERY SYSTEMS (C-F NDS), NOT SMOKING
- Where
- Italy
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Eclat Srl.
Necrotic Pulp, Regenerative Endodontic Procedures
Periapical Bleeding Versus PRF Techniques in Regenerative Endodontic Therapy: A Randomized Controlled Trial
This study investigates a biological approach that allows infected and necrotic teeth to heal themselves instead of being treated with traditional root canal therapy.
- Conditions
- Necrotic Pulp, Regenerative Endodontic Procedures, Mature Teeth, Apical Periodontitis
- Trial name
- NCT06886438
- Testing
- RVS, L-PRF, i-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Saglik Bilimleri Universitesi
Healthy Volunteers, Discoloration of Teeth
Evaluation of Tooth Sensitivity and Whitening Effects of Different Content Teeth Whitening Agents
The goal of this clinical study is to evaluate the success of different whitening agents in whitening teeth in healthy volunteers aged 18-50. Also, patients' tooth sensitivity will be assessed after application.
- Conditions
- Healthy Volunteers, Discoloration of Teeth, Bleaching Sensitivity
- Trial name
- NCT06855940
- Testing
- Bleaching Agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Betül Tokat
Tooth Discoloration, Dentin Sensitivity
Efficacy and Safety Assessment of Experimental Bleaching Agents
Tooth bleaching is widely used to treat the colors of teeth. This study compares the efficiency of two experimental bleaching gels, with and without nanoparticles, and with and without light activation versus two commercial…
- Conditions
- Tooth Discoloration, Dentin Sensitivity, Patient Satisfaction
- Trial name
- NCT06802614
- Testing
- BLEACHING GEL A, 5% NF_TiO2, BLEACHING GEL B
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Tooth Discoloration
Comparison of Color Measurements of Postgraduate Dental Students Using Different Color Determination Methods
This study evaluates the accuracy of tooth color identification skills in the anterior region using a new technique, the button technique, in comparison with other methods.
- Trial name
- Color (NCT06791694)
- Testing
- Resins, Composite
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Tooth Discoloration, Tooth Wear
Evaluation of 2-year Clinical Performance of Two Different Single Color Universal Composite Resin Restorative Materials.
Dentists have recently preferred to use composite materials and restorative techniques that allow the use of simplified clinical protocols in order to reduce the time the patient spends in the dentist's chair and minimize…
- Trial name
- NCT06125132
- Testing
- Restoration with-tooth colored material
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Baskent University
Dental Deposits, Tooth Discoloration
Phototherapy Remediation of Black Stain
This study investigates the remediation of black-stained tooth surfaces using antimicrobial photodynamic therapy. In this crossover trial, a cohort of patients received standard dental prophylactic cleaning to remove the black…
- Conditions
- Dental Deposits, Tooth Discoloration, Dental Prophylaxis
- Trial name
- NCT03309748
- Testing
- Dental prophylaxis, Dental prophylaxis + antimicrobial photodynamic therapy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Tooth Discoloration
Bleaching Procedures Performed During Treatment With Brackets and Clear Aligners
The aim of this study is to compare the effectiveness of different whitening methods used during orthodontic treatment with fixed appliances and clear aligners.
- Trial name
- NCT06716827
- Testing
- In-office bleaching system, Laser-assisted bleaching, Home-bleaching
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ahmet Yağcı
Tooth Discoloration
Clinical Efficacy of In-office Bleaching With Different Concentrations of Hydrogen Peroxide
Objective: The study evaluated the longevity, effectiveness, sensitivity and impact on the oral health-related quality of life of in-office dental bleaching using low, medium, and high concentrate hydrogen peroxide.
- Trial name
- NCT06700434
- Testing
- Bleaching treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gazi University
Tooth Discoloration, Tooth Sensitivity
Er,Cr:YSGG Laser Bleaching on Tooth Color and Sensitivity
The aim of this split-mouth clinical study was to evaluate the tooth color (ΔΕab and ΔΕ00) and whiteness (ΔWID) changes, as well as tooth sensitivity (TS) induced after performing in-office tooth bleaching procedure with or…
- Trial name
- NCT06666920
- Testing
- laser irradiation
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- Aristotle University Of Thessaloniki
Secondary Caries, Fracture Tooth
Clinical Assessment of Injectable Flowable Composite with Giomer Technology Vs High Viscosity Glass Ionomer Restorations in ART for Cancer Patients
Aim of the Study: This study will compare between injectable flowable composite (Beautifil flow plus x) and high viscosity glass ionomer (Equia Fil) by ART caries preventive protocol in high caries risk patients receiving…
- Conditions
- Secondary Caries, Fracture Tooth, Discoloration, Tooth
- Trial name
- NCT05465369
- Testing
- giomer, high viscosity glass ionomer
- Where
- Egypt
- Volunteers
- 190 people
- Sponsor
- Cairo University
Discoloration, Tooth
Bleaching Effect of Solo and Combined Kiwi Extract and Ozone and Their Impact on Enamel
ozone therapy has been extensively used in dentistry to manage wounds healing, dental caries, oral lichen planus, gingivitis and periodontitis, halitosis, osteonecrosis of the jaw, post-surgical pain, plaque and biofilms, root…
- Trial name
- NCT06582069
- Testing
- Bleaching
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University