Clinical trials: Tooth Discoloration
Gingivitis, Periodontal Diseases
Changes in Oral Health in Tobacco Cigarettes Smokers After Switching to Combustion-Free Nicotine Delivery Systems
Although the well-known detrimental effects of conventional cigarette smoking on oral health, there are still lack of evidences about the impact of less harmful alternatives (such as electronic cigarettes or heat not burn…
- Trial name
- SMILE (NCT04649645)
- Testing
- TOBACCO CIGARETTES, COMBUSTION-FREE NICOTINE DELIVERY SYSTEMS (C-F NDS), NOT SMOKING
- Where
- Italy
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Eclat Srl.
Teeth Sensitivity, Tooth Discoloration
Efficacy of CPP-ACP on Bleaching Related Sensitivity
Objective: The purpose of this randomized controlled split-mouth clinical trial was to evaluate the effectiveness of MI paste in reducing sensitivity associated vital bleaching.
- Trial name
- NCT04112706
- Testing
- CPP-ACP
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of New England
Dental Plaque, Tooth Discoloration
aPDT for the Remediation of Dental Black Stain
In today's society cosmetic dentistry plays an important role in social relationships and in important aspects of life such as job applications and recruitment processes.
- Trial name
- NCT03483376
- Testing
- Dental prophylaxis, Antimicrobial photodynamic therapy (aPDT)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Tooth Discoloration
Etiology of Black Tooth Stain in Children
The aim of the present study was to investigate the relationship between the presence of black tooth stain (BS) and dental caries incidence, dental plaque scores and to examine the colonization of Streptococcus mutans…
- Trial name
- NCT05249491
- Testing
- Microbiological evaluation of dental plaques with children with or without black tooth stain
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Ege University
Tooth Bleaching
Efficacy of Two Sonic Toothbrushes in Reducing Extrinsic Tooth Stain
The objective of the present study was to compare the effects of reduction of extrinsic stains between 2 commercially available Oclean sonic toothbrushes in comparison with an Oral-B manual toothbrush.
- Trial name
- NCT05202093
- Testing
- the Oclean Digital Visual toothbrush (2.16 N·cm torque), Oral B manual toothbrush, the Oclean Sonic Electric toothbrush (1.96 N·cm torque)
- Where
- China
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Healthy Adult Participants, Tooth Stain
Oil Pulling Whitening Mouthwash
The goal of this study is to evaluate the tooth whitening efficacy of Oil Pulling oral rinse compared to a competitor's whitening mouthwash and a water-based mouthwash (placebo).
- Trial name
- NCT07667088
- Testing
- GuruNanda natural Oil Pulling oral rinse, Therabreath Whitening Mouthwash - Dazzling Mint, GuruNanda water-based non-whitening mouthwash
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Oral Hygiene
An Efficacy Study of Stain Control of a 67% Sodium Bicarbonate Containing Toothpaste on Chlorhexidine Tooth Staining
The aim of this study is to compare the stain effect on teeth of twice daily brushing with a 67% sodium bicarbonate containing toothpaste versus standard toothpaste (not containing sodium bicarbonate) for six weeks whilst using a…
- Trial name
- NCT01962493
- Testing
- Sodium bicarbonate/ Sodium Fluoride, Sodium fluoride, Chlorhexidine digluconate
- Where
- 3 sites in United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Tooth Discoloration Following Root Canal Treatment, Tooth Discoloration
Clinical Evaluation of Discoloration Induced by Root Canal Treatment in Vital and Devital Teeth
This prospective observational study aims to evaluate and compare tooth discoloration following root canal treatment in vital and devital teeth.
- Trial name
- NCT07781969
- Testing
- Root Canal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Marmara University
Tooth Stain
A Clinical Trial to Test the Effect of a Marketed Mouth Rinse on Stain Removal
The whitening action of an investigative hydrogen peroxide/sodium fluoride containing mouth rinse will be evaluated through stain removal using mean Lobene Stain Index over 14 days compared to a currently marketed hydrogen…
- Trial name
- NCT02151058
- Testing
- Colgate® Regular Cavity Protection, Experimental Mouth Rinse, Crest® 3D White Multi-Care Whitening Rinse, Glamorous White, Fresh Mint
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Tooth Stain
Guided Biofilm Therapy Versus Conventional Polishing for Tooth Re-Staining
This study compared Guided Biofilm Therapy with conventional polishing in adults with visible extrinsic tooth staining. Each participant received Guided Biofilm Therapy on one side of the mouth and conventional polishing on the…
- Trial name
- NCT07799558
- Testing
- Guided Biofilm Therapy, Conventional Polishing
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Molar Incisor Hypomineralization, Enamel Hypoplasia
Resin Infiltration Treatment for MIH
The investigators aimed to evaluate changes in mineralisation degree, colour, and size of the lesion after Icon® in permanent teeth with MIH in 6 months.
- Conditions
- Molar Incisor Hypomineralization, Enamel Hypoplasia, Enamel Caries, Anterior Teeth
- Trial name
- NCT04685889
- Testing
- Resin infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Endodontically Treated Teeth, Tooth Discoloration
Color Dental Alteration Caused by Endodontic Treatment
The color change of endodontically treated teeth is a common concern in clinical practice. The objective of this study will be to evaluate, in vivo, the color change (ΔE00) caused by endodontic treatment.
- Conditions
- Endodontically Treated Teeth, Tooth Discoloration, Root Canal Infection
- Trial name
- NCT03841877
- Testing
- endodontic treatment
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Discoloration, Tooth, Chip Tooth
Dental Photography and Numeric Shade Quantification as a Substitute to Conventional and Instrumental Shade Matching Techniques in the Esthetic Zone
Visual shade matching is the most common method, in which a color standard from a commercially available dental shade guide is compared to and matched with the target tooth.
- Conditions
- Discoloration, Tooth, Chip Tooth, Non Vital Teeth, Trauma Dental
- Trial name
- NCT04817579
- Testing
- Digital photography combined with eLABor_aid shade analyzing software, Spectrophotometer, Conventional visual shade matching
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Anterior Teeth
Shade Matching of Universal Versus Conventional Nanohybrid Resin Composites in Class IV Restorations After Bleaching
The aim of the current study is to assess the shade matching potential of single shade universal resin composite versus conventional nanohybrid resin composite in class IV restorations after bleaching
- Trial name
- NCT05638373
- Testing
- One shade universal composite, Nanohybrid resin composite
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Discoloration, Tooth
One Year Clinical Evaluation of E-max CAD and Lava Ultimate Laminate Veneers
Restoration of anterior teeth using conservative approach allows clinicians to provide porcelain laminate veneers with excellent esthetics without extensive tooth structure removal.
- Trial name
- NCT03086928
- Testing
- lava ultimate, E.max cad
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Hypersensitivity, Tooth Discoloration
Management of Dentinal Hypersensitivity Using Two Dentifrice Technologies
This study evaluates the effectiveness of Scigates foam mouth sanitizer 2 in 1 toothpaste and mouthwash in reducing tooth sensitivity and improving tooth whitening compared to Lacalut® White \& Repair toothpaste.
- Trial name
- NCT07511530
- Testing
- Scigates Foam Mouth Sanitizer 2 in 1 Toothpaste and Mouthwash, Lacalut White and Repair Toothpaste
- Where
- Jordan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Prof. Mayyas Al-Remawi
Black Stain Dental, Dental Black Stain, Black Stain*, Black Stains, Tooth Stains
Assessment of Salivary Bacterial Level and Dental Caries Experience in a Group of Egyptian Children With Black Stained Teeth
Black stains (BS) are type of extrinsic discoloration of the tooth. It's characterized as dark lines or an incomplete coalescence of dark dots found mostly on cervical third of the crown.
- Trial name
- NCT03563469
- Testing
- Salivary bacterial and pH level
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Discoloration
Tooth Discoloration Induced by Pulpotomy Materials
Vital pulp therapy including pulpotomy is commonly used for managing teeth with carious pulp exposure instead of performing root canal therapy.
- Trial name
- NCT04346849
- Testing
- Pulpotomy
- Where
- 2 sites in Jordan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Tooth Discoloration, Color Changes During Tooth Formation
Office Bleaching Treatment by Using Rubber-cup and Air-powder Polishing Device Prophylaxis in Rondomised Clinical Design
The increasing demand for whitening teeth necessitates requirements and guidelines to ensure the efficacy of products and bleaching techniques.
- Trial name
- NCT04407910
- Testing
- AIRFLOW® Master device +Opalescence Xtra Boost., rubber-cup+Opalescence Xtra Boost.
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cukurova University