Clinical trials: Tooth Disorder
Leukodystrophy, White Matter Disease
The Myelin Disorders Biorepository Project
The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects.
- Conditions
- Leukodystrophy, White Matter Disease, Leukoencephalopathies, 4H Syndrome
- Trial name
- MDBP (NCT03047369)
- Where
- 23 sites in United States
- Volunteers
- 12,000 people
- Sponsor
- Children's Hospital of Philadelphia
Neuromuscular Diseases, Obesity (Disorder)
Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology
The ActiLiège-Adult study is a prospective, longitudinal, observational study designed to collect natural history data on adult patients with neurological or metabolic diseases affecting movement.
- Conditions
- Neuromuscular Diseases, Obesity (Disorder), Myotonic Dystrophy 1, Myasthenic Syndrome
- Trial name
- Acti-Adult (NCT07136844)
- Testing
- Syde, Dynamometric measurements of muscle strength, The 6-minute walk test (6MWT)
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Tooth Disorder, Missing Tooth/Teeth
All-ceramic Restorations: a Retrospective and Prospective Study
The goal of this observational study is to evaluate the survival and success rate of ceramic restorations on teeth and implants done in the department of fixed prosthodontics at the CHU of Liege for the last 25 years.
- Trial name
- PROCER (NCT07110220)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Mainjot Amélie
Tooth Wear, Occlusal Wear of Teeth
Evaluation of Temporomandibular Disorders and Their Association With Tooth Wear Using Digital Methods
Temporomandibular disorders (TMDs) are considered complex conditions in dental practice due to their multifactorial etiology. Over the years, various diagnostic methods have been introduced; however, the most widely accepted…
- Conditions
- Tooth Wear, Occlusal Wear of Teeth, Occlusal Analysis, TMJ
- Trial name
- NCT07081204
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Tooth Extraction, Molar, Third
Efficacy of Artificial Intelligence-Generated Music Therapy in Reducing Dental Anxiety Among Adults Undergoing Impacted Third Molar Extraction
Music therapy is widely used in dentistry as it helps patients remain distracted during procedures, particularly during implant placement or third molar extraction.
- Trial name
- NCT06998979
- Testing
- Music therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Coimbra
Anxiety and Fear, Tooth Disease
Virtual Reality Used During Tooth Extraction and Extirpation Treatment
This study carriy out to evaluate the effect of virtual reality glasses used during tooth extraction and extirpation treatment under local anesthesia on anxiety and fear in children aged 7-10 years.
- Trial name
- NCT06315816
- Testing
- virtual reality glasses used during tooth extraction and extirpation treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Murat Bektaş
Transdiagnostic Psychopathology, Attrition
Digital Rewards and Retention in a M-health App
Attrition and user engagement are two challenges that eHealth interventions struggle with. Attempts to address this have been previously made through gamification, instructional design and using different types of incentives.
- Conditions
- Transdiagnostic Psychopathology, Attrition, Engagement, Depression, Anxiety
- Trial name
- DIGITALRCT (NCT06883773)
- Testing
- Multipurpose Online Tool, No intervention
- Where
- Romania
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University of Bucharest
Mood Disorders
Neurofilament Light Chain Correlation With Severity of Symptoms and Cognitive Decline in Mood Disorders
Explore correlation of neurofilament light chain serum level and severity of symptoms and cognitive impairment in mood disorders Explore How novel brain markers as neurofilament light chain can be useful in detection and…
- Trial name
- NCT06877442
- Testing
- serum level of neurofilament light chain
- Volunteers
- 90 people
- Sponsor
- Assiut University
Dental Research, Orthodontics
Treatment of the Mandibular Dental Crowding With and Without Corticotomy Surgery
The use of corticotomy surgery in addition to orthodontic standard treatment could accelerate the treatment. Corticotomy involves vertical interdental incisions of the gingiva and the bone with a very low thickness.
- Conditions
- Dental Research, Orthodontics, Surgery, Oral, Maxillofacial Surgery
- Trial name
- CORTICO (NCT03967002)
- Testing
- Test group with corticotomy surgery
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ardentis Cliniques Dentaires
Primary Ciliary Dyskinesia, Caries,Dental
Assessment of Oral Health Status of Children With Primary Ciliary Dyskinesia
The aim of this study is to compare the oral health findings, salivary parameters and pediatric oral health related quality of life of children with Primary Ciliary Dyskinesia (PCD) with healthy children
- Conditions
- Primary Ciliary Dyskinesia, Caries,Dental, Quality of Life, Saliva Altered
- Trial name
- NCT06618209
- Testing
- physical and chemical methods, biochemical methods, Oral Findings
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marmara University
Tooth Eruption Disorder
Digital Planning and Guided Dual Technique in Aesthetic Crown Lengthening
Excessive gingival exposure, commonly named gingival smile, results in a dentogingival disharmony. One of the gingival smile treatment is the aesthetics-related crown lengthening surgery (ACL) to provide a adequate clinical crown…
- Trial name
- NCT04922086
- Testing
- Conventional aesthetic crown lengthening surgery, Guided dual aesthetic crown lengthening surgery
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Alfenas
Dental Pulp Necrosis, Disorder of Tooth Development
A Clinical Study to Compare Two Revascularization Protocols to Treat Non-vital Teeth With Incomplete Root Formation
Both methods tested in this study disinfect the non-vital root canals and induce blood clot formation inside the root canal. One method places calcium hydroxide inside the root canal after disinfection and the blood clot is…
- Trial name
- NCT01827098
- Testing
- Endodontic Regeneration
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Michigan
Stroke, Stroke (CVA) or TIA
The Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3)
Stroke is a major cause of death and disability worldwide, frequently resulting in persistent cognitive deficits among survivors.
- Conditions
- Stroke, Stroke (CVA) or TIA, Dementia, Vascular, Cerebrovascular Disorders
- Trial name
- IC3 (NCT05885295)
- Testing
- MRI brain, Blood tests, cognitive assessments
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Tooth Development Disorder
Assessment of the Occlusal Characteristics
The objective of this study is to assess the occlusal characteristics of primary dentition among Egyptian preschool children.
- Trial name
- NCT05670652
- Testing
- clinical examination
- Volunteers
- 362 people
- Sponsor
- Cairo University
Hysterosalpingography, Anxiety
The Effect of Using Music and Natural Landscape Paintings on Pain Level, Anxiety and Analgesic Use of Women During HSG
The study was planned as a randomized controlled study in order to evaluate the use of music and natural scenery paintings in women who underwent HSG procedure, their pain level, anxiety and post-procedure analgesic use.
- Conditions
- Hysterosalpingography, Anxiety, Pain
- Trial name
- NCT05712954
- Testing
- music group, video group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ŞERİVAN KARAKUT
Impacted Third Molar Tooth, Temporomandibular Disorder
Assessing a New Jaw Support Device During Third Molar Extractions
During mandibular 3rd molar (wisdom tooth) extractions, when a downward force is placed on the patient's jaw, the patient must tense his/her jaw muscles to oppose it.
- Trial name
- NCT03975920
- Testing
- The Restful Jaw Device
- Where
- 4 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Teeth, Impacted, Tooth-loss
The Influence of Sedation and General Anesthesia to Patients' Psycho-emotional State Undergoing Wisdom Teeth Extraction
The aim of the study is to evaluate, wheather the sedation or general anesthesia in third molar extractions influence the patient's psycho-emotional status.
- Conditions
- Teeth, Impacted, Tooth-loss, Anxiety, Fear
- Trial name
- NCT04259463
- Testing
- Third molars extraction
- Where
- Lithuania
- Volunteers
- 53 people
- Sponsor
- Inesa Astramskaitė
Vertical Fracture of Root of Tooth (Disorder)
Assessment of Vertical Root Fracture Resistance of Endodontically Treated Teeth Instrumented by Single Endodontic Files
The purpose of this study is the assessment of vertical root fracture resistance of roots prepared with three different single endodontic rotary files in extracted human mandibular premolar roots.
- Trial name
- NCT05286073
- Testing
- Endodontic Root Canal Treatment
- Where
- Pakistan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Nutrition Disorders in Old Age, Caries,Dental
LifE Style, Nutrition and Oral Health in Care Givers (LENTO)
The LENTO study sample includes the caregivers and their clients living in eastern Finland. The aims of this study are 1. to study the nutritional status, oral health, coping, functional capacity and quality of life 2.
- Conditions
- Nutrition Disorders in Old Age, Caries,Dental, Dentures, Oral Mucositis
- Trial name
- NCT04003493
- Testing
- Nutrition and oral health intervention
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Tooth Eruption Disorder
Effects of a Gum Gel Intended to Treat Signs and Symptoms of Teething
Teething discomfort is a widespread disorder affecting a very high percentage of infants. The use of hyaluronic acid gels has been shown in the last 20 years to be an effective tool, generally devoid of side effects, in reducing…
- Trial name
- NCT04879836
- Testing
- Teething Gel, Teething Ring
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- University of Urbino "Carlo Bo"