Clinical trials: Tooth Lesions
Deep Caries, Pulp Exposure, Dental
Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions.
- Conditions
- Deep Caries, Pulp Exposure, Dental, Dental Caries
- Trial name
- NCT04052685
- Testing
- Selective removal to soft dentin (SRSD), Selective removal to firm dentine (SRFD)
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- burcu gözetici
Dental Abrasion, Gingival Recession
Evaluation of Two Resin Composites and Two Adhesives for a Novel Restorative Protocol to Treat Cervical Lesions
Non-carious cervical lesion is frequently associated with gingival recession, resulting in a combined lesion that has a different treatment prognosis when the two lesions appear alone.
- Conditions
- Dental Abrasion, Gingival Recession, Composite Resins
- Trial name
- NCT03215615
- Testing
- Periodontal surgery, Total Etch adhesive, Universal Adhesive
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Endodontic Disease
Effect of Different Irrigation Solutions on Postoperative Pain and Lesion Healing
In this study researchers plan to conduct, three different irrigation solutions that are responsible for the release of growth factors necessary for the success of regenerative endodontic treatments will be used.
- Trial name
- NCT06386991
- Testing
- Using ethylenediaminetetraacetic acid (EDTA), citric acid ((MONO/ANH) and etidronic acid (HEBP) to clean root canals during regenerative endodontic treatments
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Evaluation of the Efficacy of SPR-G Barrier Coat Versus Fluoride Varnish Versus MI Paste in the Treatment of Early White Spot Lesions in Pediatric Patients
In-Vivo randomized clinical trial to compare between the clinical performance of fluoride varnish versus MI paste (CPP_ACP) and the PRG- Barrier coat material concerning enamel remineralization, arrest of active early lesions…
- Trial name
- NCT05202821
- Testing
- PRG Barrier Coat, Fluoride varnish, MI paste
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries
High-strength Glass-ionomer Dental Restorations
The purpose of this study is to extend our knowledge concerning the clinical performance of two dental filling materials in molars. The study will compare two high-strength glass-ionomer filling materials.
- Trial name
- ROCK (NCT01523613)
- Testing
- Chemfil ROCK Glassionomer restoration, Fuji IX GP Extra Glassionomer restoration
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Mathilde Peters, DMD, PhD
Endodontic Disease, Periodontitis
Endo-perio Disease - Treatment Outcomes Using Conventional and Hydraulic Calcium Silicate Sealer With or Without LPRF
The endodontic periodontal-disease is characterized by the involvement of the pulp and periodontal disease in the same tooth. The anatomic connections between the dental pulp and the periodontium provide a pathway for perio-endo…
- Trial name
- NCT05681754
- Testing
- Experimental: RCT using hydraulic calcium silicate sealer and L-PRF + GTR, Experimental: RCT using conventional sealer and L-PRF + GTR, Experimental: RCT using hydraulic calcium silicate sealer and GTR
- Where
- United Kingdom
- Volunteers
- 115 people
- Sponsor
- King's College London
Tooth; Lesion, White Spot Lesions
Remineralisation of White Spot Lesions by Elmex® gelée in Post-orthodontic Patients
The aim of this study is to monitor the effect of intraoral topical high fluoride application on the development of white spot lesions (WSL) after orthodontic treatment with multibracket appliances and to compare it to a placebo.
- Trial name
- NCT01329731
- Testing
- elmex® gelée
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Gaba International AG
Pulp Necroses, Periapical Lesion
Magnetic Resonance Imaging (MRI) of Pulp Regeneration
The present study was conducted to test whether pulp-like tissue can be regenerated in mature teeth with closed apex? And whether the size of the apical diameter affects the success of REPs? And whether Magnetic resonance imaging…
- Conditions
- Pulp Necroses, Periapical Lesion, Regeneration
- Trial name
- NCT03804450
- Testing
- Regenerative endodontic procedures (REPs)
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Pulp Necrosis, Periapical Diseases
Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars in Children
This randomized clinical trial aims to compare the clinical and radiographic success of calcium hydroxide-iodoform paste and modified triple antibiotic paste when used for the treatment of necrotic primary molars in children…
- Conditions
- Dental Pulp Necrosis, Periapical Diseases, Dental Caries, Primary Teeth
- Trial name
- NCT07773805
- Testing
- Calcium Hydroxide, Iodoform, paste, modified triple antibiotic paste
- Volunteers
- 50 people
- Sponsor
- Cairo University