Clinical trials: Tooth Sensitivity, open to volunteers
Gingival Recession, Generalized, Gingival Recession Generalized Moderate
Using Calcium Hydroxylapatite To Treat Gum Recession and Tooth Hypersensitivity
Study Purpose and Objectives: This study will utilize calcium hydroxylapatite (CaHA) to treat recession and hypersensitivity of the gums. The objectives of the study are: 1.
- Conditions
- Gingival Recession, Generalized, Gingival Recession Generalized Moderate, Gingival Recession Localized Moderate, Tooth Sensitivity
- Trial name
- NCT06826391
- Testing
- Calcium hydroxylapatite
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- American Academy of Facial Esthetics
Dentin Hypersensitivity, Tooth Hypersensitivity
Diode Laser Plus CPP-ACPF vs CPP-ACPF Alone for Dentin Hypersensitivity
This study aims to compare the effectiveness of diode laser photobiomodulation combined with CPP-ACPF varnish versus CPP-ACPF varnish alone in reducing dentin hypersensitivity.
- Trial name
- NCT07449169
- Testing
- Diode laser photobiomodulation combined with CPP-ACPF varnish, CPP-ACPF varnish
- Volunteers
- 70 people
- Sponsor
- Cairo University
Dentin Sensitivity
Effect of an Experimental Cannabidiol Gel on Tooth Sensitivity
The goal of this clinical trial will be to evaluate the effect applying an experimental gel based on cannabidiol oil (CBD) on tooth sensitivity induced by tooth bleaching with 35% hydrogen peroxide (HP).
- Trial name
- NCT07027566
- Testing
- Potassium nitrate and sodium fluoride, Cannabidiol (CBD) Gel, Natrosol 4% Gel
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Universidade Federal do Para
Post-operative Sensitivity, Dentin Hypersensitivity
Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations
The aim of this study is to compare the effectiveness of Gluma desensitizer in reducing post-operative sensitivity following composite restorations in posterior teeth.
- Conditions
- Post-operative Sensitivity, Dentin Hypersensitivity, Dental Caries, Tooth Sensitivity After Composite Restorations
- Trial name
- NCT07188142
- Testing
- Drug/Agent: Gluma Desensitizer, Drug/Agent: No desensitizer (Control)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Beenish Hassan
Hypomineralization Molar Incisor, Hypersensitivity Dentin
Photobiomodulation and New Restorative Material for Teeth With MIH on Control of Hypersensitivity and Longevity
Introduction: Molar incisor hypomineralization (MIH) is a qualitative defect of enamel development that occurs in the mineralization phase. MIH affects one or more permanent molars and, occasionally, permanent incisors.
- Trial name
- NCT06538142
- Testing
- Photobiomodulation + Restoration with Self-cure Composite Resin, Restoration with Self-cure Composite Resin, Photobiomodulation + Restoration with Photopolymerizable Bulk-fill Composite Resin
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dentin Sensitivity, Dentine Hypersensitivity, Tooth Sensitivity
Comparative Efficacy of Laser Systems and Fluoride in Managing Dentinal Hypersensitivity: RCT
This randomized controlled clinical trial aims to compare the effectiveness of Erbium laser (2940 nm), Diode laser (650 nm), combination Diode laser with fluoride varnish, and fluoride varnish alone in treating dentinal…
- Trial name
- DHLT (NCT07141576)
- Testing
- Erbium laser (2940 nm): Infrared light energy, Diode laser (650 nm): Visible red light energy, Fluoride varnish
- Volunteers
- 96 people
- Sponsor
- Cairo University
Dentinal Hypersensitivity, Plaque, Dental
Evaluation of Dental and Periodontal Health After IPR in Patients in Orthodontic Treatment With Clear Aligners
This study aimed to evaluate dental and periodontal health after interproximal enamel reduction and to compare Laser diode (a device used in the Orthodontic Program) and sodium fluoride (often used in the Orthodontic Program and…
- Conditions
- Dentinal Hypersensitivity, Plaque, Dental, Bleeding Gum
- Trial name
- NCT06685016
- Testing
- Evaluation of Dentin hypersensitivity with VAS scale
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Dental Pulp Disease, Dental Pain and Sensation Disorder
Comparison of Post Cementation Sensitivity Between RMGIC and GIC as Luting Materials in a Randomized Clinical Trial
This randomized controlled trial aims to compare post-cementation sensitivity between resin-modified glass ionomer cement (RMGIC) and conventional glass ionomer cement (GIC) as luting materials.
- Trial name
- RMGICvsGIC (NCT07102121)
- Testing
- luting material applaication with Modified Glass Ionomer Cement (RMGIC)
- Where
- Pakistan
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- Saidu College of Dentistry
Hypersensitivity Dentin, Fluoride Varnishes
Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity
This randomized controlled clinical trial aims to determine whether different fluoride varnish formulations reduce dentin hypersensitivity (DH) in young adults diagnosed with DH.
- Trial name
- NCT07286344
- Testing
- Aqueous fluoride varnish, 9,500 ppm NaF, Resin/rosin-based varnish, 22,600 ppm NaF
- Where
- Chile
- Volunteers
- 92 people
- Sponsor
- University of Concepcion, Chile
Non-Carious Cervical Lesions (NCCLs), Dentin Hypersensitivity
Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical Study
The aim of this split-mouth clinical study is to compare the effectiveness of D Blue diode laser application and ProSylc bioactive glass powder application in reducing dentin hypersensitivity in patients with non-carious cervical…
- Trial name
- NCCL-DH (NCT07648147)
- Testing
- D Blue Diode Laser, ProSylc Bioactive Glass Powder
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Cukurova University
Dentin Hypersensitivity
Exposed Hypersensitive Dentin Treated With Fluoride Iontophoresis With Remineralizing Agents
The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity.
- Trial name
- NCT06837779
- Testing
- Fluoride Iontophoresis with Acidulated Phosphate Fluoride, Remineralization with sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Discoloration, Dentin Sensitivity
Efficacy and Safety Assessment of Experimental Bleaching Agents
Tooth bleaching is widely used to treat the colors of teeth. This study compares the efficiency of two experimental bleaching gels, with and without nanoparticles, and with and without light activation versus two commercial…
- Conditions
- Tooth Discoloration, Dentin Sensitivity, Patient Satisfaction
- Trial name
- NCT06802614
- Testing
- BLEACHING GEL A, 5% NF_TiO2, BLEACHING GEL B
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Dentine Hypersensitivity
Three Different Topically Applied Materials as Non-invasive Treatment of Sensitivity in Permanent Teeth With Molar Incisor Hypomineralization
This clinical study main goal is to investigate the effectiveness of nano hydroxy apatite crystal varnish and potassium nitrate gel as a non invasive approach in managing Dentin Hypersensitivity in MIH-affected teeth.
- Trial name
- NCT07056855
- Testing
- nano hydroxy apatite varnish Intervention (1), Potassium Nitrate Gel, Varnishes, Fluorid
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Demineralization, Tooth Sensitivity
Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study
This study evaluates the clinical performance, marginal integrity, surface wear, color stability, and postoperative sensitivity of graphene-reinforced CAD/CAM indirect restorations (inlays, onlays, overlays) in molars affected by…
- Conditions
- Tooth Demineralization, Tooth Sensitivity, Enamel Mineralization Disorders, Tooth Sensitivity After Composite Restorations
- Trial name
- NCT07329244
- Testing
- Graphene-reinforced CAD/CAM polymer (G-CAM®)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Tooth Discoloration, Tooth Staining
Peroxide Versus Non-Peroxide In-Office Tooth Bleaching
This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems.
- Trial name
- BECTS (NCT07818031)
- Testing
- peroxide -based in office tooth bleaching, non-peroxide -based in office tooth bleaching
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minia University
Dentin Hypersensitivity, Erosive Tooth Wear
Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.
The goal of this observational study is to learn about tooth wear and tooth sensistivity and reasons for these conditions in five locations throughout the United States.
- Trial name
- NCT07195357
- Testing
- epidemiological
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Indiana University
Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction
THBC/CGF for Alveolar Bone Regeneration: A Real-World Study
This study aims to combine real-world research with relevant bone repair materials and techniques to improve alveolar bone resorption in extraction sockets following impacted wisdom tooth removal, while achieving effective bone…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction, Tooth, Impacted
- Trial name
- NCT07779421
- Testing
- Temperature-sensitive hydroxybutyl chitosan-loaded concentrated growth factor, Temperature-sensitive hydroxybutyl chitosan, Autologous Concentrated Growth Factor
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
Celiac Disease, Dentin Hypersensitivity
Hydroxyapatite-Based Home Treatment for Dentin Sensitivity in Celiac Patients
This single-center, randomized controlled clinical trial aims to evaluate the effectiveness of a home-based treatment using hydroxyapatite-based oral care products in adult patients with celiac disease who exhibit enamel…
- Conditions
- Celiac Disease, Dentin Hypersensitivity, Tooth Demineralization
- Trial name
- CELIADENT (NCT07069127)
- Testing
- Biorepair Toothpaste and Mousse, Biorepair® Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Dentin Hypersensitivity, Post Operative Sensitivity Control
Dipotassium Oxalate for Postoperative Sensitivity in NCCLs
Postoperative sensitivity is a common complication following Class V composite restorations, particularly in non-carious cervical lesions (NCCLs).
- Trial name
- DIPOX-RCT (NCT07540299)
- Testing
- Dipotassium Oxalate Gel
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Dentin Hypersensitivity
Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity
This study will be performed to assess the effect of inert prepared tooth paste loaded with Calcium Silicate Nanoparticles (CSNPs) and compare it to another one containing Sodium Fluoride Nanoparticles in the management of…
- Trial name
- NCT06557980
- Testing
- toothpaste
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University