Clinical trials: Toothbrushes
Plaque, Dental, Gingivitis
Evaluation of Toothbrush Bristles in Plaque Reduction
The purpose of this cross-over clinical research is to evaluate the cleaning efficacy of toothbrushes tufted with two types of tapered bristles and end rounded bristles in removal of interdental plaque with clinical measurement…
- Trial name
- NCT04681885
- Testing
- Tapered bristles A, Tapered bristles B, End rounded bristles
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sunstar Americas
Plaque Induced Gingivitis, Toothbrushing
Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis
Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque.
- Conditions
- Plaque Induced Gingivitis, Toothbrushing, Compliance
- Trial name
- NCT07308522
- Testing
- AI toothbrush, Manual toothbrush, Electric toothbrush
- Where
- Iraq
- Volunteers
- 33 people
- Sponsor
- University of Baghdad
Periodontitis, Dental Plaque
At-Home Care for Subjects With Periodontitis
The effect of use of powered toothbrushing in patients exhibiting periodontal inflammation has been observed repeatedly in clinical studies conducted over a 20+ year period.
- Trial name
- NCT04254770
- Testing
- ADA approved Manual Toothbrush, Marketed Power Toothbrush
- Where
- United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Gingival Recession, Gingival Abrasion
Evaluation of Gingival Fissures Associated With Soft and Medium Toothbrushes
Gingival fissures (GF) have been suggested as risk indicators for clinical attachment loss (CAL) and gingival recession, especially in free surfaces and in patients with low plaque scores.
- Conditions
- Gingival Recession, Gingival Abrasion, Wounds and Injuries
- Trial name
- NCT03367481
- Testing
- Toothbrush type
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Dental Plaque, Toothbrushing
Efficacy of an U-shape Automatic Electric Toothbrush in Plaque Removal
Over time, many different types of manual and electric toothbrushes have been produced. A systematic review has shown that some electric toothbrushes are more effective at removing bacterial plaque than manual toothbrushes.
- Trial name
- NCT04119583
- Testing
- U-shape Automatic Electric Toothbrush, Usual home toothbrushing procedure, Conventional Electric Toothbrush
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florence
Periodontitis, Dental Plaque
Powered vs. Manual Toothbrushing in Stage 3-4 Periodontitis
This study compares the effectiveness of powered and manual toothbrushes in reducing gum bleeding and dental plaque in people with stage 3 or 4 periodontitis.
- Conditions
- Periodontitis, Dental Plaque, Gingival Bleeding
- Trial name
- NCT06980714
- Testing
- Powered, Manual
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Periodontal Diseases
Placebo Controlled Trial of a Titanium Dioxide Semiconductor Toothbrush on Mild-to-moderate Gum Disease
The effects on indices of gingivitis/periodontitis will differ between study arms in which the titanium dioxide semiconductor toothbrush is used, compared to an otherwise identical toothbrush with an inert resin core in place of…
- Trial name
- NCT00167466
- Testing
- Soladey-3 toothbrush
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Saskatchewan
Plaque Induced Gingivitis
Safety and Efficacy of U-Shaped Sonic Toothbrush on Plaque and Gingivitis
The goal of this 30 day, randomized, two group, parallel, examiner-blind clinical study is to evaluate the safety and efficacy of AutoBrush® 360° U-shaped Sonic Toothbrush on supragingival dental plaque and gingivitis, compared…
- Trial name
- NCT06126250
- Testing
- Power sonic toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Lander Enterprises, LLC
Dental Devices, Home Care
Study of an Experimental Toothbrush for Treatment and Prevention of Gingivitis
This study is 6 weeks long with 6 visits to a clinical site. People participating in this study will be asked to brush their teeth two times a day with a provided toothbrush.
- Trial name
- NCT01224158
- Testing
- Experimental Power Toothbrush, Flat trimmed Manual Toothbrush
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Plaque Removal
Comparison of New and 3-Month-Old Toothbrush in the Removal of Plaque in Children
This study aimed to validate or invalidate non-inferiority in the plaque removal efficacy of old versus new toothbrushes in the hands of 7-9 year old children.
- Trial name
- NCT00836784
- Testing
- old toothbrush, New tooth brush
- Where
- Iran
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Periodontal Diseases, Diabetes Mellitus
Comparison of Two Oral Hygiene Routines on the Glycemic Control for Type 2 Diabetes Patients With Chronic Periodontitis
This study aims to compare two common oral hygiene routines on the improvement of glycemic control and oral health parameters in moderate to severe periodontitis patients with uncontrolled type 2 diabetes (T2DM).
- Trial name
- NCT05260814
- Testing
- Electric toothbrush with smart phone app
- Volunteers
- 40 people
- Sponsor
- Harvard School of Dental Medicine
Gingival Inflammation
Toothbrush Wear and Its Effect on Subgingival Inflammation Using Two Different Brushing Techniques
Toothbrush plaque removal, along with interproximal flossing, helps to maintain the oral cavity free from periodontal diseases and dental caries.
- Trial name
- NCT03158350
- Testing
- Instructed Brushing Method
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tufts University
Plaque, Dental
The Effectiveness of the Water Jet Device in Removing Dental Plaque Around Orthodontic Braces in Adolescents
The aim of this study was to evaluate the effectiveness of the water jet in removing dental plaque around the orthodontic braces in adolescents.
- Trial name
- NCT06098976
- Testing
- Water Jet, Manual toothbrush
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Damascus University
Dental Plaque, Halitosis
Efficacy of Different Toothbrushes and Hygiene Regimen
To evaluate: 1) Evaluate the efficacy of a regimen commercially available versus brush alone on established plaque and gingivitis on adolescents.
- Trial name
- NCT04216069
- Testing
- Total 12 regimen, Toothbrushing alone
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Tooth Discoloration
Efficacy of Manual Toothbrushes in Removing Tooth Stains
Efficacy of Manual Toothbrushes in Removing Tooth Stains: A 6-Week Clinical Research Study.
- Trial name
- NCT06486974
- Testing
- NaF, Na MFP
- Where
- Dominican Republic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Full Mouth Plaque Score (FMPS)
Effectiveness of Autobrush® Versus Manual Toothbrush Among Adolescents With Fixed Orthodontic Appliances
This study is a randomized crossover clinical trial designed to compare the effectiveness of a U-shaped automatic toothbrush (Autobrush®) versus a conventional manual toothbrush in reducing dental plaque among adolescents…
- Trial name
- NCT07537790
- Testing
- U-shaped toothbrush (Autobrush®), Manual regular toothbrush
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Shahad Abudawood
Oral Hygiene, Toothbrushing
Open-label Trial Evaluating Four Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste, and Mouthwash
The purpose of this open-label, randomized controlled clinical trial, is to provide preliminary clinical data (efficacy on plaque and gingival sensitivity, and safety and tolerability of two types of toothpaste, a mouthwash, and…
- Conditions
- Oral Hygiene, Toothbrushing, Dental Plaque
- Trial name
- NCT05999175
- Testing
- the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days., the mint toothpaste and mouthwash are used with the scalar toothbrush 33 medium with antibacterial " Spazzolino tau-marin®" 3 times a day after the main meals for 28 days., subjects of this group will use their routine oral hygiene products.
- Where
- 2 sites in Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Biokosmes Srl
Oral Hygiene
Effectiveness of T-shaped Toothbrush
This study evaluated the effectiveness of two manual toothbrushes, the T-shaped toothbrush (Denson™, Malaysia) and a conventional toothbrush (Kid's Soft Toothbrush, Colgate) in removing plaque and maintaining gingival health…
- Trial name
- NCT03989479
- Testing
- Brushing demonstration using T shaped toothbrush, Brushing demonstration using conventional toothbrush
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Gingivitis, Periodontal Diseases
Results From Objective Brushing Data Saved From a Powered Toothbrush Related to Values for Oral Health
For this study, 213 individuals were recruited. During the Baseline examination, each participant received a powered toothbrush and was carefully instructed on how to use the toothbrush and recommended using it for at least 2…
- Trial name
- NCT05941611
- Testing
- Powered toothbrush
- Where
- Sweden
- Volunteers
- 213 people
- Sponsor
- Blekinge Institute of Technology
Movement Disorders and Physical Impairments
Assessing the Colgate Assist Handle Toothbrush in Individuals With Impairment of Hand Movement.
User experiences of Colgate Assist Handle toothbrush as indicated by questionnaire and interview
- Trial name
- NCT06632704
- Testing
- Colgate Toothbrush assist
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Colgate Palmolive