Clinical trials: Toothbrushing, open to volunteers
Plaque Induced Gingivitis, Toothbrushing
Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis
Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque.
- Conditions
- Plaque Induced Gingivitis, Toothbrushing, Compliance
- Trial name
- NCT07308522
- Testing
- AI toothbrush, Manual toothbrush, Electric toothbrush
- Where
- Iraq
- Volunteers
- 33 people
- Sponsor
- University of Baghdad
Oral Bacterial Colonization, Oral Hygiene
Effects of Three Oral Hygiene Protocols on Oral Bacteria in Intensive Care Patients
Patients in intensive care may develop changes in the bacteria found in their mouths. Some of these bacteria can cause infections, and patients who cannot clean their own teeth depend on staff to provide oral care.
- Trial name
- NCT07868549
- Testing
- Mechanical Oral Hygiene, Chlorhexidine, Hexetidine
- Where
- Croatia
- Volunteers
- 86 people
- Sponsor
- University of Zagreb
Oral Health, Dental Caries
WhatsApp Messages to Improve Mothers' Oral Health Knowledge and Children's Toothbrushing
Tooth decay is one of the most common health problems in young children in Saudi Arabia. Brushing twice a day with fluoride toothpaste is one of the most effective ways to prevent it, but preschool children cannot do this…
- Conditions
- Oral Health, Dental Caries, Health Behavior, Oral Hygiene
- Trial name
- NCT07765654
- Testing
- Standardized Face-to-Face Oral Health Education, WhatsApp-Based Oral Health Messages
- Volunteers
- 106 people
- Sponsor
- King Abdulaziz University
Bacteremia, Infective Endocarditis
Reducing Risk for Infective Endocarditis
This clinical trial is studying if bacteria found in a participant's bloodstream after brushing their teeth can be prevented with a dental cleaning and more education on how to best brush and care for their teeth.
- Trial name
- PIE-B (NCT05721781)
- Testing
- Oral Hygiene instruction, Dental Cleaning
- Where
- 6 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Oral Complication
A Comparative Study of Three Oral Care Methods in NIMV Patients in Intensive Care
This study aims to examine the effects of different oral care methods on oral health in patients receiving non-invasive mechanical ventilation (NIMV) in the intensive care unit.
- Trial name
- NCT07200297
- Testing
- Active Comparator: Control, Experimental: Electric Toothbrush, Experimental: Manual Toothbrush
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- SÜMEYYE BİLGİLİ TEKİN
Gingivitis, Dental Plaque
Clear Aligner Cleaning: Brushing, Chlorhexidine, and BlueM Effects on Oral Microbial Ecology and Periodontal Indices
This randomized crossover study will assess how three aligner-cleaning methods affect early supragingival oral microbial ecology and periodontal health in adults using clear aligners.
- Trial name
- NCT07307716
- Testing
- Mechanical toothbrushing (fluoride toothpaste), Chlorhexidine mouthwash (0.2%), Oxygen-based cleanser
- Where
- Saudi Arabia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Autism Spectrum Disorder, Child
AI Toothbrush and Visual Pedagogy to Improve Oral Hygiene in Children With Autism Spectrum Disorder
This randomized clinical trial evaluates the effectiveness of an AI-enabled electric toothbrush and visual pedagogy materials in improving oral hygiene among children with autism spectrum disorder (ASD).
- Conditions
- Autism Spectrum Disorder, Child, Oral Health, Artificial Intelligence
- Trial name
- NCT07160517
- Testing
- Visual Pedagogy and Manual Toothbrushing
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Fanconi Anaemia
Non-invasive Characterisation of Oral Carcinomas in Patients With Fanconi Anaemia
Patients with Fanconi anaemia have an increased risk of developing squamous cell carcinoma of the head and neck. In addition, their genetic vulnerability limits the use of genotoxic treatments such as radiotherapy and…
- Trial name
- Fanc-Oral (NCT07242261)
- Testing
- Oral brushing
- Volunteers
- 115 people
- Sponsor
- Institut Jean-Godinot
Plaque Induced Gingivitis
Evaluation of Safety and Efficacy of Bixdo Ultra Compact Water Flosser
The objective of the present randomized controlled trial is to evaluate the safety and efficacy of the use of Bixdo A30 Pro Ultra Compact Water Flosser (also referred to as the "Bixdo A30 Portable Water Flosser Travel Set") in…
- Trial name
- NCT06352645
- Testing
- Bixdo Ultra Compact Water Flosser, Manual toothbrush
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Tufts University
Manual Toothbrush
Children's Compliance With Toothbrushing Using Manual U-shaped Toothbrush Versus Regular Toothbrush
To assess the child's compliance towards manual U-shaped toothbrush versus regular manual toothbrush.
- Trial name
- NCT06554782
- Testing
- manual u-shaped toothbrush
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, Dental Plaque
Powered vs. Manual Toothbrushing in Stage 3-4 Periodontitis
This study compares the effectiveness of powered and manual toothbrushes in reducing gum bleeding and dental plaque in people with stage 3 or 4 periodontitis.
- Conditions
- Periodontitis, Dental Plaque, Gingival Bleeding
- Trial name
- NCT06980714
- Testing
- Powered, Manual
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Specific Learning Disabilities, Dental Plaque
Plaque Removal Efficiency in Children With Specific Learning Disabilities
This study aims to evaluate the effectiveness of toothbrushing education on plaque removal in children aged 7-12 years with specific learning disabilities (SLD) and to compare their plaque removal performance with healthy…
- Conditions
- Specific Learning Disabilities, Dental Plaque, Oral Hygiene
- Trial name
- PRE-SLD (NCT07611942)
- Testing
- Standardized Toothbrushing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Elderly, Periodontal Disease
Oral Hygiene Assistance Training Program
This is an oral health study with a nursing home staff training program and product intervention.
- Conditions
- Elderly, Periodontal Disease, Gingivitis, Caries,Dental
- Trial name
- NCT07807397
- Testing
- Stannous Fluoride Toothpaste (SnF), sodium fluoride 5000 ppm, cetylpyridinium chloride (0.075%) and zinc alcohol free mouthwash
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Plaque Reduction
Digital vs. Parent Modeled Toothbrushing
This prospective randomized controlled trial will aim to evaluate the effectiveness of two methods of delivering oral hygiene instruction to children aged 3 - 6 years: parent-modeled toothbrushing (control) and the MoodBrush…
- Trial name
- NCT07441148
- Testing
- MoodBrush Digital Application
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Gingivitis, Gingival Bleeding
Safety and Efficacy of Flaus Electric Flosser on Plaque and Gingivitis Compared to a Manual Toothbrush
This is a study to evaluate the safety and the efficacy of an electric flosser (interproximal cleaning aid), when used with a manual toothbrush, on gingivitis and dental plaque removal.
- Conditions
- Gingivitis, Gingival Bleeding, Dental Plaque
- Trial name
- NCT07779564
- Testing
- Electric Flosser, Manual Toothbrush
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Flaus, Inc
Autism Spectrum Disorder
Mobile App-Based Intervention to Improve Toothbrushing in Children and Teens With Autism
The goal of this clinical trial is to test whether the autism-friendly app improves toothbrushing outcomes compared to a control app with only a digital mirror and countdown timer among children and teens (ages 8-17 years) with…
- Trial name
- BU (NCT07446413)
- Testing
- Brush Up App, Brush Down App
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Washington
Autism
Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
The goal of this proposed trial will modify an existing toothbrushing app for teens with autism and compare toothbrushing outcomes with a control app.
- Trial name
- NCT06208722
- Testing
- Testing a Mobile App to Improve Toothbrushing Skills and Habits in Teens With Autism
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Washington
Dental Plaque Accumulation, Oral Hygiene Education Methods
Evaluation of a Novel Dual-Headed Toothbrush Design for Periodontal Health: Split-Mouth Randomized Blind Clinical Trial
The goal of this clinical trial is to evaluate the effectiveness and patient satisfaction of a novel dual-headed toothbrush design compared to a conventional single-headed toothbrush in adult dental professionals aged 22-45 years…
- Conditions
- Dental Plaque Accumulation, Oral Hygiene Education Methods, Toothbrushing
- Trial name
- NCT07030088
- Testing
- Dual-Headed Manual Toothbrush, Conventional Single-Headed Manual Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Dar Al Uloom University
Toothbrushing, Gingivitis
Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery
The study is a randomized clinical trial to compare the effectiveness of a dual light ultrasonic toothbrush on periodontal health in orthodontic patients undergoing surgery.
- Conditions
- Toothbrushing, Gingivitis, Cleft Lip and Palate
- Trial name
- NCT06122805
- Testing
- Toothbrush
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles