Clinical trials: Tophaceous Gout
Gout
Pegylated Recombinant Mammalian Uricase (PEG-uricase) as Treatment for Refractory Gout
The purpose of this study is to determine whether PEG-uricase (a chemically modified recombinant mammalian enzyme that degrades uric acid) is effective in controlling hyperuricemia in patients with chronic gout, who cannot…
- Trial name
- NCT00111657
- Testing
- Pegloticase
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- John Sundy
Tophaceous Gout
Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and Febuxostat
This study will compare the serum uric acid lowering effects, clinical benefits, and safety of lesinurad in combination with febuxostat to febuxostat alone in patients with tophaceaous gout.
- Trial name
- CRYSTAL (NCT01510769)
- Testing
- Lesinurad, Febuxostat
- Where
- 124 sites in United States, Australia and 4 more
- Volunteers
- 330 people
- Sponsor
- Ardea Biosciences, Inc.