Clinical trials: Total Gastrectomy
Adenocarcinoma of Esophagogastric Junction.
Impact on Quality of Life in Patients Undergoing Total Gastrectomy or Proximal Gastrectomy for Adenocarcinoma of Esophagogastric Junction
The purpose of this study is to find out more about differences of the quality of life in patients undergoing total gastrectomy or proximal gastrectomy for adenocarcinoma of esophagogastric junction.
- Trial name
- GCQOL01 (NCT01697917)
- Testing
- Total Gastrectomy or Proximal Gastrectomy
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Fudan University
Gastric Cancer
Laparoscopic vs Open Total Gastrectomy for Gastric Cancer
The aim of the present study is to demonstrated the the safety and feasibility of laparoscopic total gastrectomy comparing with open total gastrectomy.
- Trial name
- NCT05537129
- Testing
- Total Gastrectomy
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Fudan University
Hyperglycaemia, Total Gastrectomy
The Effect of Perioperative Hyperglycemia on Anastomotic Leaks After Total Gastrectomy
Esophagojejunostomy anastomosis is used in total gastrectomy surgeries. Anastomotic leakage is a serious complication seen after these surgeries and is associated with increased morbidity and mortality.
- Conditions
- Hyperglycaemia, Total Gastrectomy, Anastomotic Leaks
- Trial name
- NCT07140991
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Taner Abdullah
Adenocarcinoma of the Stomach
Pharmacokinetic Study of Capecitabine After Total Gastrectomy for Stomach Adenocarcinoma
The purpose of this study is to evaluate the pharmacokinetics (PK) of capecitabine in patients who have undergone a total gastrectomy.
- Trial name
- NCT00871273
- Testing
- capecitabine
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Total Gastrectomy, Gastric Cancer
Reconstruction With a Lawrence-Hunt Jejunal Pouch After Total Gastrectomy
The aim of the study is to establish the efficacy of jejunal pouch reconstruction in reducing dumping syndrome in patients undergoing total gastrectomy, ultimately enhancing postoperative quality of life and nutritional status.
- Trial name
- REJOY (NCT06967571)
- Testing
- Jejunal Pouch reconstruction.
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gastric Cancer
Comparison Partial Versus Total Omentectomy in Minimal Invasive Distal Gastrectomy for cT3/4a Gastric Cancer (KLASS-10)
For advanced gastric cancer, surgical resection is the only curable therapeutic strategy. According to minimally invasive approach is adopted in various field of oncologic surgery, laparoscopic gastrectomy with lymph node…
- Trial name
- NCT06608381
- Testing
- Arm I (Total omentectomy),, Arm II (Partial omentectomy)
- Where
- South Korea
- Volunteers
- 440 people
- Sponsor
- Gangnam Severance Hospital
Gastroesophageal Reflux Disease, Excessive Weight Loss
Sleeve Gastrectomy With Reestablishment of the Acute Angle of His (SG-REACH) in Obese Patients
Gastroesophageal reflux disease (GERD) is one of the most common chronic conditions that can affect one's quality of life. Laparoscopic sleeve gastrectomy (LSG) has become a popular technique and currently is the most frequently…
- Conditions
- Gastroesophageal Reflux Disease, Excessive Weight Loss, Total Weight Loss, Sleeve Gastrectomy
- Trial name
- SG-REACH (NCT05452980)
- Testing
- reestablishment of the acute angle of His, sleeve gastrectomy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhen Jun Wang
Gastric Cancer
OGT-assisted Overlap Esophagojejunostomy Versus Traditional Overlap Method
Abstract Background Our previous studies have shown OGT method significantly simplified overlap esophagojejunostomy with good short-term outcomes, and provided new perspectives for optimizing esophagojejunostomy.
- Trial name
- OGT (NCT05450835)
- Testing
- OGT group, Overlap group
- Where
- 12 sites in China
- Volunteers
- 344 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastric Cancer
Comparative Analysis of Short-Term Therapeutic Effects Between the π-Shaped and Overlap Methods for Esophagogastrostomy in Totally Laparoscopic Total Gastrectomy
As of now, although the safety of π-shaped anastomosis and the overlap method has been separately discussed in different contexts, there have been few studies considering a direct comparison of the results of these two methods.
- Trial name
- NCT06383793
- Testing
- overlap
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Northern Jiangsu People's Hospital
Gastric Cancer
Comparison of Laparoscopic Proximal Gastrectomy and Laparoscopic Total Gastrectomy
Experimental: Laparoscopic proximal gastrectomy Laparoscopy proximal gastrectomy with esophago-jejunostomy, gastro-jejunostomy and jejuno-jejunostomy (double tract reconstruction).
- Trial name
- NCT02892643
- Testing
- Laparoscopic proximal gastrectomy, Laparoscopic total gastrectomy
- Where
- 16 sites in South Korea
- Volunteers
- 138 people
- Sponsor
- Seoul National University Bundang Hospital
Gastric Cancer
Long-term Oncologic Outcomes of Robotic Versus Laparoscopic Total Gastrectomy for Advanced Gastric Cancer
This study is a retrospective, single-center, controlled and observation trial comparing robotic total gastrectomy with D2 lymph nodal dissection for locally advanced gastric cancer patients with laparoscopic procedure.
- Trial name
- NCT05181306
- Testing
- Robotic-assisted Total Gastrectomy with D2 Lymphadenectomy, Laparoscopic-assisted Total Gastrectomy with D2 Lymphadenectomy
- Where
- China
- Volunteers
- 430 people
- Sponsor
- Southwest Hospital, China
Gastric Cancer
Trial for Application of Laparoscopic Total Gastrectomy With Lymph Node Dissection for Gastric Cancer (KLASS-06)
Although Laparoscopic gastrectomy for both early and locally advanced gastric cancer has gained popularity, the use of laparoscopic total gastrectomy for proximal advanced gastric cancer is still limited to some experienced…
- Trial name
- NCT03385018
- Testing
- Radical total gastrectomy with D2 (D2 - #10) lymph node dissection by laparoscopic approach, Radical total gastrectomy with D2 (D2 - #10) lymph node dissection by open conventional approach
- Where
- South Korea
- Volunteers
- 772 people
- Sponsor
- Yonsei University
Obesity, Morbid, Weight Regain After Bariatric Surgery
Weight Loss and Comorbidity Outcomes After Revisional Bariatric Surgery
Some people who have had weight-loss (bariatric) surgery do not lose enough weight, regain much of the weight they lost, see obesity-related diseases such as diabetes or high blood pressure return, or develop complications of the…
- Conditions
- Obesity, Morbid, Weight Regain After Bariatric Surgery, Insufficient Weight Loss After Bariatric Surgery, Complication of Bariatric Surgery
- Trial name
- NCT07880691
- Testing
- Revisional bariatric surgery
- Volunteers
- 96 people
- Sponsor
- Kasr El Aini Hospital
Stomach Neoplasms, Minimally Invasive Surgery
Intracorporeal Versus Extracorporeal Roux-en-Y Esophagojejunostomy During Laparoscopic Total Gastrectomy for Gastric Cancer
To date, Roux-en-Y esophagojejunostomy transabdominal extracorporeally by circular stapler was the most common used method during laparoscopy-assisted total gastrectomy for gastric cancer, even though it was not totally…
- Conditions
- Stomach Neoplasms, Minimally Invasive Surgery, Anastomosis
- Trial name
- NCT02085031
- Testing
- Intracorporeal Roux-en-Y esophagojejunostomy, Extracorporeal Roux-en-Y esophagojejunostomy
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastric Cancer
Gastric Decompression After Sub-total Gastrectomy
The purpose of this study is to test the utility of the nasogastric tube, which is used to decompress and as "guardian" of gastro-jejunal anastomosis, in patients undergoing distal subtotal gastrectomy for gastric cancer with…
- Trial name
- NCT01073046
- Testing
- Naso-Gastric/Jejunal Tube
- Where
- Italy
- Volunteers
- 276 people
- Sponsor
- Catholic University, Italy
Gastric Cancer
Evaluation of the Efficacy of Distal Gastrectomy for the Treatment of Gastric Cancer (a Case Series)
Case series of a retrospective study of patients operated for distal adenocarcinoma of the stomach, either by total gastrectomy or distal gastrectomy at Ibn Rochd University Hospital in Casablanca, with the analysis of outcome of…
- Trial name
- NCT05068635
- Volunteers
- 30 people
- Sponsor
- Sylvestre KABURA
Stomach Neoplasm, Robotic Surgery
Clinical Efficacy Between Robotic and Laparoscopic Total Gastrectomy in Patients With Clinical Stage I Gastric Cancer
The purpose of this study is to explore the clinical efficacy between robotic and laparoscopic total gastrectomy in patients with clinical Stage I gastric cancer
- Trial name
- NCT03524300
- Testing
- Robotic Assisted Total Gastrectomy, Laparoscopic Assisted Total Gastrectomy
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Fujian Medical University
Sleeve Gastrectomy, Pre-cardial Fat Pad
Preserving the Pre-cardial Fat Pad During Sleeve Gastrectomy on Postoperative Gastroesophageal Reflux
Gastroesophageal reflux disease (GERD) is one of the most common chronic conditions that can affect one's quality of life. Laparoscopic sleeve gastrectomy (LSG) has become a popular technique and currently is the most frequently…
- Conditions
- Sleeve Gastrectomy, Pre-cardial Fat Pad, Excessive Weight Loss, Total Weight Loss
- Trial name
- Pad and SG (NCT06732661)
- Testing
- Preserve pre-cardial fat pad, Dissect pre-cardial fat pad
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Chao Yang Hospital
Gastric Tumor
Impact of Roux-En-Y Pouch Reconstruction Compared With Conventional Roux-En-Y Reconstruction on Quality of Life in Patients Undergoing Total Gastrectomy
The purpose of this study is to find out more about differences of the quality of life in patients undergoing Roux-En-Y pouch reconstruction and conventional Roux-En-Y reconstruction.
- Trial name
- GCQOL02 (NCT01697943)
- Testing
- Roux-En-Y Pouch Reconstruction or Conventional Roux-En-Y Reconstruction
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Fudan University
Sarcopenia, Malnutrition
Prognostic Value of CT-guided Sarcopenia for Surgical Outcomes in Esophagetomy and Total Gastrectomy Due to Neoplasia
The purpose of this study is to assess the degree of sarcopenia by CT and to analyze its association with morbidity and mortality after esophagectomy and / or total gastrectomy.
- Conditions
- Sarcopenia, Malnutrition, Gastrostomy, Esophagostomy Complication
- Trial name
- NCT05723783
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Barretos Cancer Hospital