Clinical trials: Total Gastrectomy
Gastric Cancer, Splenic Hilum Lymph Nodes Dissection
Laparoscopic-assisted Total Gastrectomy Versus Open Total Gastrectomy With Splenic Hilum Lymph Nodes Dissection
This study investigates the safety and feasibility of laparoscopic-assisted total gastrectomy with spleen-preserving splenic hilum lymph node dissection for proximal advanced gastric cancer and compares the early results of this…
- Conditions
- Gastric Cancer, Splenic Hilum Lymph Nodes Dissection, Total Gastrectomy
- Trial name
- NCT02711033
- Testing
- Laparoscopic-assisted total gastrectomy, Open total gastrectomy
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Gastric Cancer
Study On Safety Of Laparoscopic Total Gastrectomy For Clinical Stage I Gastric Cancer
This CLASS02-01 trial is a prospective, multicenter trial for laparoscopic total gastrectomy (LTG) and open total gastrectomy (OTG) in patients with clinical stage I (T1N0M0、T1N1M0、T2N0M0) gastric cancer.
- Trial name
- CLASS02-01 (NCT03007550)
- Testing
- Laparoscopic total gastrectomy, Open total gastrectomy
- Where
- China
- Volunteers
- 227 people
- Sponsor
- Shanghai Zhongshan Hospital
Gastric Adenocarcinoma, Gastrectomy
PG Versus TG for Advanced PGC
We conducted a retrospective study on patients with pathological stage II-III PGC who underwent PG or TG from 2013 to 2023. Propensity score-matching was applied to adjust for tumor size and stage between the PG and TG groups at…
- Trial name
- NCT06614439
- Testing
- proximal gastrectomy, total gastrectomy
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- National Taiwan University Hospital
Gastrostomy
The Effect of Total Intravenous Anesthesia and Volatile Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Laparoscopic or Robotic Assisted Gastrectomy
The aim of this study was to investigate the effects of total intravenous and inhalation anesthesia on the damage of endothelial glucocorticoids by comparing the concentration of syndecan-1 before and after laparoscopic or…
- Trial name
- NCT04183296
- Testing
- propofol, sevoflurane
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Yonsei University
Gastric Cancer, Robotic Gastrectomy
the Clinical Efficacy of Robotic and Laparoscopic Radical Total Gastrectomy in Locally Advanced Middle and Upper Gastric Cancer
To evaluate the clinical efficacy (safety, feasibility and long-term efficacy) of robotic radical total gastrectomy and laparoscopic radical total gastrectomy in patients with locally advanced middle and upper gastric…
- Trial name
- NCT05235932
- Testing
- Robotic radical total gastrectomy with D2 lymphadenectomy, Laparoscopic radical total gastrectomy with D2 lymphadenectomy
- Where
- China
- Volunteers
- 570 people
- Sponsor
- Fujian Medical University
Gastric Cancer
Validation of a Model for Predicting Anastomotic Leakage
This study will validate a machine learning model for predicting anastomotic leakage of esophagogastrostomy and esophagojejunostomy.
- Trial name
- NCT05646290
- Where
- China
- Volunteers
- 512 people
- Sponsor
- Jichao Qin
Laparoscopic Gastrectomy, Laparoscopic Bursectomy
Laparoscopic Total Gastrectomy With Versus Without Bursectomy
Bursectomy is widely performed in open surgery for advanced gastric cancer in East Asia. However laparoscopic D2 radical total gastrectomy with complete bursectomy is difficult and rare performed.
- Conditions
- Laparoscopic Gastrectomy, Laparoscopic Bursectomy, A Left Outside Bursa Omentalis Approach
- Trial name
- NCT03117283
- Testing
- Laparoscopic D2 radical total gastrectomy with bursectomy using a left outside bursa omentalis approach, Laparoscopic D2 radical total gastrectomy without bursectomy
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Gastric Cancer, Stomach Cancer
Total Neoadjuvant FLOT Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer
The main goal of this study is to investigate the proportion of participants with locally advanced gastric and gastroesophageal adenocarcinoma without previous treatment during the last 5 years who can tolerate all planned cycles…
- Conditions
- Gastric Cancer, Stomach Cancer, GastroEsophageal Cancer, Gastric Adenocarcinoma
- Trial name
- OCTASUR (NCT06028737)
- Testing
- Docetaxel, Oxaliplatin, Leucovorin
- Where
- 2 sites in Lithuania, Ukraine
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Clinical Oncology
Gastric Cancer
Laparoscopy-assisted Total Gastrectomy for Clinical Stage I Gastric Cancer (KLASS-03)
The purpose of this study is to evaluate the safety and feasibility of laparoscopy-assisted total gastrectomy for early upper gastric cancer compared with open total gastrectomy.
- Trial name
- KLASS-03 (NCT01584336)
- Testing
- LATG
- Where
- 10 sites in South Korea
- Volunteers
- 168 people
- Sponsor
- Soonchunhyang University Hospital
Early Oral Nutrition After Total Gastrectomy, Gastric Cancer
Trial on Impact on the Hospital Stay, of an Early Oral Nutrition Protocol Applied to Patients After Total Gastrectomy. (DOPGT_2015)
This is a prospective randomized controlled clinical trial to clarify the effect of early oral nutrition introduction after total gastrectomy in gastric cancer patients on the length of hospital stay, comparing an experimental…
- Trial name
- NCT03257280
- Testing
- Early oral nutrition
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Hospital Universitari de Bellvitge
Gastric Cancer
Laparoscopy-assisted Proximal Gastrectomy Versus and Laparoscopy-assisted Total Gastrectomy
The choice of surgical strategy for patients with proximal gastric cancer is controversial mainly because proximal gastrectomy is infamous for high rates of reflux symptoms and anastomotic stricture.
- Trial name
- PRAPT (NCT01433861)
- Testing
- Laparoscopy-assisted gastrectomy
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Seoul National University Bundang Hospital
Gastric Cancer
Comparison of Laparoscopic and Open Total Gastrectomy for Locally Advanced Gastric Cancer
Evidence of implementation of laparoscopic total gastrectomy (LTG) for locally advanced gastric cancer (GC) remains inadequate. This study aimed to compare short- and mid-term outcomes of LTG versus open total gastrectomy (OTG)…
- Trial name
- LOTA (NCT06202105)
- Testing
- Laparoscopic gastrectomy
- Where
- 3 sites in Vietnam
- Volunteers
- 210 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Locally Advanced Gastric Cancer
Proximal Gastrectomy vs Total Gastrectomy in Locally Advanced Upper Gastric Cancer After Neoadjuvant Therapy
We plan to evaluate the efficacy and safety of proximal gastric vs. total gastric radical resection after SOX combined with anti-PD-1 neoadjuvant therapy in locally advanced upper gastric cancer
- Trial name
- TJHGC01 (NCT06597227)
- Testing
- Proximal radical gastrectomy, Total radical gastrectomy
- Where
- China
- Volunteers
- 404 people
- Sponsor
- Guihua Wang
Vitamin B12 Deficiency
Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total Gastrectomy
Pernicious anemia develops in 50% of total gastrectomized due to gastric cancer patients. Lack of intrinsic factor, which is secreted by parietal cell from stomach wall causes deficiency of cobalamin, which, in final, causes…
- Trial name
- NCT00699478
- Testing
- mecobalamin
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Gastric Cancer, Total Gastrectomy
Enhanced vs. Routine Follow-Up After Total Gastrectomy for Advanced Gastric Cancer: A Randomized Controlled Trial
The goal of this clinical trial is to compare the effectiveness of enhanced follow-up with standard follow-up in postoperative patients with advanced gastric cancer who have undergone radical gastrectomy.
- Conditions
- Gastric Cancer, Total Gastrectomy, Postoperative Care, Quality of Life
- Trial name
- NCT06468969
- Testing
- Enhanced Follow-up
- Volunteers
- 158 people
- Sponsor
- Fudan University
Laparoscopic Sleeve Gastrectomy
Total Intravenous Anesthesia Versus Inhalation Anesthesia on Postoperative Liver Function
The pandemic of obesity has become a serious issue of public health worldwide as the size of the obese population has almost tripled over the last four decades and continues to riseزThe epidemic of obesity has led to a…
- Trial name
- NCT06423846
- Testing
- Total intravenous anesthesia group, sevoflurane group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Postprandial Hypoglycemia, End-stage Renal Disease (ESRD)
Anakinra for the Treatment of Postprandial Hypoglycemia in a Patient With Total Gastrectomy and End-Stage Renal Disease
Post-meal low blood sugar (postprandial hypoglycemia) is a common problem after certain stomach surgeries like gastric bypass or stomach removal.
- Conditions
- Postprandial Hypoglycemia, End-stage Renal Disease (ESRD), Gastrectomy, Glucose Metabolism Disorders
- Trial name
- AnPHy-ReD (NCT07580079)
- Testing
- Anakinra (interleukin-1 receptor antagonist)
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Marc Donath
Stomach Neoplasms
Robotic Total Gastrectomy for Locally Advanced Proximal Gastric Cancer
The purpose of this study is to explore the clinical Efficacy of robotic assisted spleen-preserving No. 10 lymph node dissection for patients with locally advanced upper third gastric adenocarcinoma（cT2-4a, N-/+, M0）.
- Trial name
- NCT03524287
- Testing
- Robotic Assisted No.10 Lymph Node Dissections
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fujian Medical University
Colon or Colorectal Resection, Partial or Total Gastrectomy
Development and Validation of a Predictive Score for Surgical Site Infections
More than 8 millions surgical interventions are carried out each year in France. Postoperative complications, in particular infectious, can occur in 10 to 60% of cases and are the cause of postoperative revision in 30% of cases…
- Conditions
- Colon or Colorectal Resection, Partial or Total Gastrectomy, Pancreaticoduodenectomy, Hepatectomy
- Trial name
- SPRED (NCT05523713)
- Testing
- Peripheral venous blood samples
- Where
- 4 sites in France
- Volunteers
- 283 people
- Sponsor
- Hopital Foch
Total Laparoscopic Distal Gastrectomy, Locally Advanced Gastric Cancer
Comparison of Short Term Outcomes Between Totally Laparoscopic and Laparoscopy-Assisted Distal Gastrectomy With Billroth-II Reconstruction and D2 Lymphadenectomy for Locally Advanced Gastric Cancer
Prospective Randomized Controlled Multicenter Clinical Trial for Comparison of Safety Between Totally Laparoscopic Distal Gastrectomy(TLDG) and Laparoscopy-Assisted Distal Gastrectomy(LADG) With Billroth-II Reconstruction and D2…
- Trial name
- NCT02365896
- Testing
- TLDG or LADG
- Volunteers
- 176 people
- Sponsor
- Fujian Cancer Hospital