Clinical trials: Total Gastrectomy
Stomach Neoplasms
Randomized Controlled Trials on Clinical Outcomes of Totally Laparoscopic Versus Laparoscopy Assisted Total Gastrectomy for Gastric Cancer
The purpose of this study is to explore clinical outcomes of totally laparoscopic versus laparoscopy assisted total gastrectomy for gastric cancer.
- Trial name
- NCT03006263
- Testing
- Totally Laparoscopic Total Gastrectomy, Laparoscopy Assisted Total Gastrectomy
- Volunteers
- 110 people
- Sponsor
- Fujian Medical University
Gastroesophageal Junction Cancer, Stomach Neoplasms
Proximal Versus Total Gastrectomy for Locally Advanced Siewert Type II-III Gastroesophageal Junction Cancer
This multicenter prospective randomized clinical trial aims to compare the safety and oncological effectiveness of proximal gastrectomy and total gastrectomy in patients with locally advanced Siewert type II-III gastroesophageal…
- Conditions
- Gastroesophageal Junction Cancer, Stomach Neoplasms, Esophageal Neoplasms
- Trial name
- SIEWERT-RCT (NCT07482566)
- Testing
- Proximal Gastrectomy, Total Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Nurettin Şahin
Gastric Cancer
Safety Comparison of Total Laparoscopic Proximal Gastrectomy With or Without Preservation of the Celiac Branch of the Vagus Nerve for Early Upper Gastric Cancer: A Randomized Controlled Clinical Trial
This prospective, single-center, randomized, controlled, non-inferiority clinical trial aims to compare the safety and postoperative quality of life of early upper gastric cancer patients undergoing total laparoscopic proximal…
- Trial name
- TLPG-CBVP (NCT07142122)
- Testing
- Total laparoscopic proximal gastrectomy with preservation of both the hepatic and celiac branches of the vagus nerve, followed by double-tract reconstruction., Total laparoscopic proximal gastrectomy with preservation of the hepatic branch of the vagus nerve but deliberate resection of the celiac branch, followed by double-tract reconstruction.
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Fujian Cancer Hospital
Gastric Cancer, Robotic Gastrectomy
Total Robotic Versus Robotic Assisted Distal Gastrectomy for Gastric Cancer
To evaluate the clinical efficacy (safety, feasibility and long-term efficacy) of total robotic versus robotic assisted distal gastrectomy for patients with gastric cancer (cT1-4a, N0/+, M0).
- Trial name
- NCT04795063
- Testing
- Total Robotic Distal Gastrectomy, Robotic-Assisted Distal Gastrectomy
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Fujian Medical University
Gastric Cancer, Surgery
Preoperative Immunonutrition in Laparoscopic Total D2 Gastrectomy
Immunonutrition (IN) appears to reduce infective complications and in-hospital length of stay (LOS) after gastrointestinal surgery. More specifically, it seems to be beneficial also in gastric cancer surgery.
- Conditions
- Gastric Cancer, Surgery, Laparoscopic, Gastric Neoplasm
- Trial name
- NCT05259488
- Testing
- immunonutrition
- Volunteers
- 51 people
- Sponsor
- University of Rome Tor Vergata
POCD - Postoperative Cognitive Dysfunction, Recovery Time
The Effects of Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy
In this study, the investigators want to examine the effects of intravenous anesthetic drugs and gases on cognitive functions in the postoperative period in individuals who will undergo surgery for obesity.
- Conditions
- POCD - Postoperative Cognitive Dysfunction, Recovery Time, Postoperative Neurocognitive Disorder, Postoperative Delirium
- Trial name
- NCT07637357
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Gastric Cancer
Laparoscopic Versus Open Gastrectomy With Splenic Hilum Lymph Nodes Dissection
Splenic hilum remains challenging during total gastrectomy with D2 lymphadenectomy.The application of minimally invasive surgery for advanced gastric cancer is gaining popularity.
- Trial name
- NCT02980861
- Testing
- Laparoscopic total gastrectomy, Open total gastrectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Gastric Cancer
ONS in Gastric Cancer After Total Gastrectomy
Gastric cancer patients after total gastrectomy will be randomized to oral nutritional supplement group or control group at discharge. Patients will receive 6 months of oral nutritional supplement or normal diet after discharge.
- Trial name
- NCT05823272
- Testing
- ONS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jinling Hospital, China
Gastric Cancer
Novel Esophago-Jejunal Anastomosis Method During Totally Laparoscopic Total Gastrectomy
Laparoscopic gastrectomy became a good option for early gastric cancer. Surgical trend is gradually changed to totally laparoscopic gastrectomy from laparoscopy-assisted gastrectomy requiring mini-laparotomy.
- Trial name
- NCT02330913
- Testing
- Intracorporeal esophagojejunostomy
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Keimyung University Dongsan Medical Center
Excessive Weight Loss, Total Weight Loss
Sleeve Gastrectomy With Uncut Jejunal Bypass (SG-uncut JJB) Verus Sleeve Gastrectomy in Obese Patients
Among various bariatric procedures, sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) are the most frequently performed procedures worldwide.
- Conditions
- Excessive Weight Loss, Total Weight Loss, Sleeve Gastrectomy, Jejunojejunal Bypass
- Trial name
- NCT04534504
- Testing
- SG-JJB
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhen Jun Wang
Gastric Cancer
Safety and Efficacy of OGT Method Versus the Traditional Overlap Method
Introduction: The safety and efficiency of OGT-assisted method have not yet been compared with conventional overlap approach. Methods Retrospectively analyses the data of 155 gastric/gastroesophageal junction (G/GEJ) cancer…
- Trial name
- OGT (NCT05442502)
- Testing
- The overlap guiding tube(OGT) method, The conventional overlap method
- Where
- China
- Volunteers
- 155 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Esophagojejunal Anastomotic Leak
Impact of Endo-vac Therapy for Esophago-jejunal Anastomotic Leak
The goal of this observational study is to assess the impact of endoscopic vacuum therapy in patients who underwent total gastrectomy due to gastric cancer and developed esophago-jejunal anastomotic leakage.
- Trial name
- ENDO-VAL (NCT07295236)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Clinical Oncology
Gastrectomy, Gastric Cancer
Comparison of Textbook Outcomes Between Laparoscopic and Open Total Gastrectomy for Gastric Cancer
Gastric cancer patients underwent total gastrectomy with curative intent between in a single center were included in this retrospective study.
- Trial name
- NCT06758934
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Gastrectomy, Gastric Carcinoma
The Influence of Splenic Artery Characteristics in Gastric Cancer Surgery
The northwest Chinese population has unique anatomical characteristics of splenic artery due to ethnic differences, which has an important impact on the development and prognosis of laparoscopic radical total gastrectomy.
- Trial name
- NCT06680362
- Where
- China
- Volunteers
- 176 people
- Sponsor
- xiaohua li
Gastric Cancers
Analysis of Lymph Node Metastasis and Tumor Deposit in the Short Gastric Mesentery Following Total Gastrectomy for Gastric Cancer
This study aims to explore lymph node metastasis in the short gastric mesentery following total gastrectomy with D2 lymphadenectomy plus complete mesogastric excision, providing evidence-based medicine for standardizing lymph…
- Trial name
- zytg001 (NCT06728878)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Jichao Qin
Splenic Hilum Lymph Nodes Dissection
3D Versus 2D Laparoscopic Total Gastrectomy With Splenic Hilum Lymph Nodes Dissection
The investigators will perform a prospective randomized comparison between 3D and 2D laparoscopic total gastrectomy with splenic hilum lymph nodes dissection.
- Trial name
- NCT02984787
- Testing
- 3D Laparoscopic total gastrectomy, 2D Laparoscopic total gastrectomy
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Chinese PLA General Hospital
Gastric Cancer, ERAS
ERAS in Totally Laparoscopic Total Gastrectomy for Gastric Cancer
The number of totally laparoscopic total gastrectomy is gradually increasing, but the safety of ERAS in these term is still unknown and further multicenter randomized controlled studies are needed.
- Conditions
- Gastric Cancer, ERAS, Laparoscopic Gastrectomy
- Trial name
- NCT06489288
- Testing
- ERAS protocol
- Where
- China
- Volunteers
- 2,656 people
- Sponsor
- Xijing Hospital
Gastric Cancer, Nutrition Disorders
Functional Jejunal Interposition Improve Nutritional Status After Total Gastrectomy
The purpose of this study is to find out whether the nutritional status of patients undergoing Functional Jejunal Interposition is better than those with Roux-en-Y After Total Gastrectomy for Gastric Cancer.
- Trial name
- FJINS (NCT01996059)
- Testing
- Functional Jejunal Interposition, Roux-en-Y
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Sun Yat-sen University
Gastric Cancer, GastroEsophageal Cancer
A Study of Minimally Invasive Proximal Gastrectomy Versus Minimally Invasive Total Gastrectomy for Gastric and Gastroesophageal Junction Cancers
Participants will a diagnosis of gastroesophageal junction (GEJ) adenocarcinoma and will have either a minimally invasive proximal gastrectomy (MIPG) or a minimally invasive total gastrectomy (MITG) as part of their routine care.
- Conditions
- Gastric Cancer, GastroEsophageal Cancer, Gastroesophageal Junction Adenocarcinoma
- Trial name
- NCT06243757
- Testing
- MDASI-GI
- Where
- 8 sites in United States
- Volunteers
- 4 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Anesthesia, Total Intravenous Anesthesia
The Effect of Anesthetic Methods on Gastrointestinal Motility
The goal of this randomized controlled single blinded study is to compare the effect of the type of anesthesia on gastrointestinal motility in patients scheduled for laparoscopic sleeve gastrectomy.
- Trial name
- NCT05951686
- Testing
- Desflurane, Remifentanil infusion, Fresh gas
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Bozyaka Training and Research Hospital