Clinical trials: Total Hip
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
28mm Ceramic-on-Ceramic Total Hip Replacement Study
This study is intended to gather medium (0-5 years) and long-term (6-10 years) information regarding the performance and safety of the commercially available Ceramax™ Ceramic on Ceramic Total Hip System.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
- Trial name
- COC28 (NCT01657435)
- Testing
- Ceramax Acetabular System
- Where
- 13 sites in United States, Canada
- Volunteers
- 185 people
- Sponsor
- DePuy Orthopaedics
Anticoagulation
Multi-center Study to Evaluate the Safety of Apixaban (BMS-562247) in Indian Subjects Undergoing Elective Total Knee Replacement or Total Hip Replacement Surgery
The primary purpose of this protocol is to evaluate the safety of Apixaban in prophylaxis of Venous Thromboembolism (VTE) in Indian patients undergoing elective total knee or hip replacement
- Trial name
- NCT01884337
- Testing
- Apixaban
- Where
- 20 sites in India
- Volunteers
- 557 people
- Sponsor
- Bristol-Myers Squibb
Hip Disease
ACE Acetabular Cup UK Multi-centre PMCF Study
A total hip replacement is one of the most successful and cost-effective surgical procedures in orthopaedics, and involves replacing both the hip ball and socket.
- Trial name
- NCT04123431
- Testing
- Total Hip Replacement
- Where
- United Kingdom
- Volunteers
- 225 people
- Sponsor
- JRI Orthopaedics
Joint Diseases
28 mm Ceramic-on-Ceramic Acetabular Cup Total Hip Replacement Study
The study is designed to evaluate artificial hips with a 28 mm ceramic head and a ceramic liner to determine whether they perform as well as artificial hips with a 28 mm ceramic head and a polyethylene liner.
- Trial name
- NCT00208507
- Testing
- 28 mm ceramic head on ceramic acetabular liner., 28 mm ceramic head on polyethylene liner
- Where
- 2 sites in United States
- Volunteers
- 264 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis, Avascular Necrosis
A Clinical Investigation of ArComXL® Polyethylene in Total Hip Replacement
The purpose of this data collection is to determine long term survival rate of ArComXL® highly cross-linked polyethylene
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- NCT00698152
- Where
- 5 sites in United States
- Volunteers
- 149 people
- Sponsor
- Zimmer Biomet
Venous Thromboembolism, Thromboembolism
A Phase 2b Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Hip Arthroplasty
The objective of this study is to compare the efficacy, safety of DU-176b 30mg or DU-176b 15mg versus enoxaparin sodium for the prevention of venous thromboembolism in patients after elective total hip arthroplasty.
- Conditions
- Venous Thromboembolism, Thromboembolism, Thrombosis, Embolism and Thrombosis
- Trial name
- NCT01203098
- Testing
- DU-176b 15mg, DU-176b 30mg, Enoxaparin sodium 20 mg (=2000IU)
- Where
- 3 sites in Japan, Taiwan
- Volunteers
- 264 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Hip Arthropathy
Ambispective Study to Assess the Safety and the Performance of SAGITTA EVL R Stem
This clinical study is conducted to collect data on hip arthroplasty with the SAGITTA EVL-R revision femoral stems manufactured by SERF.
- Trial name
- 2022-09 (NCT06096155)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Societe dEtude, de Recherche et de Fabrication
Osteoarthritis, Hip, Hip Disease
Wright Medical Technology Metal-on-Metal 522 Post-Market Surveillance Study
This study is in response to the Food and Drug Administration (FDA) call to all manufacturers with 510(k) clearance for metal-on-metal (MoM) total hip arthroplasty (THA) devices to conduct postmarket surveillance studies.
- Conditions
- Osteoarthritis, Hip, Hip Disease, Hip Osteoarthritis, Joint Pain
- Trial name
- NCT03450733
- Testing
- Wright Medical Technology Metal-on-Metal Total Hip System
- Where
- 4 sites in United States
- Volunteers
- 173 people
- Sponsor
- MicroPort Orthopedics Inc.
Total Knee Arthroplasty; Total Hip Arthroplasty
Health Partner Evaluation at Providence
This is a prospective, mixed methods, multi-center, randomized, comparative, controlled study. Providence Health \& Services will enroll a total of 296 subjects (18 years or older) who are electing to have total knee or hip…
- Trial name
- NCT03443284
- Testing
- Health Partner, Standard Care
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- DePuy Orthopaedics
Tissue Reaction, Elevated Blood Ion Levels
An MRI Investigation of Soft Tissues in Total Hip Arthroplasty
Retrospective study to comply with FDA's post-market surveillance order. The purpose of the study is to contact patients who have received a Biomet metal-on-metal product as their primary total hip arthroplasty device.
- Trial name
- MoM_MRI (NCT01750606)
- Where
- 5 sites in United States
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Dimolegin® (60 mg) Given Once Daily in Patients Undergoing Total Hip or Knee Replacement Compared to Enoxaparin
This clinical study aims to evaluate the efficacy and safety of the anticoagulant Dimolegin® compared to low molecular weight heparin (Clexane®) for the prevention of venous thromboembolic events (VTE) in patients undergoing…
- Conditions
- Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Venous Thromboembolism (VTE), Prevention
- Trial name
- NCT07124819
- Testing
- Sodium enoxaparin, Dimolegin
- Where
- 8 sites in Russia
- Volunteers
- 215 people
- Sponsor
- Avexima Diol LLC
Osteoarthritis, Avascular Necrosis
Post-market Surveillance Study With the HYPERION Hip Endoprosthesis System in Defect Reconstruction
The study is a multi-center, prospective, non-controlled, consecutive cohort post market surveillance study. The objective of this study is to obtain survival and clinical outcome data on the Hyperion® system in primary and…
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Functional Deformities
- Trial name
- NCT03382665
- Where
- 3 sites in Germany
- Volunteers
- 70 people
- Sponsor
- Zimmer Biomet
Postmenopausal Osteoporosis
Study of Transitioning From Alendronate to Denosumab
The study will evaluate the efficacy and safety of transitioning postmenopausal women on current alendronate therapy to denosumab.
- Trial name
- NCT00377819
- Testing
- alendronate, Denosumab (AMG 162)
- Volunteers
- 504 people
- Sponsor
- Amgen
Linear or Emi-linear Incisions, Total Hip Arthroplasty
Prevena™ Incision Management System Over Primarily Closed Hip and Knee Incisions in Patients Immediately Post Total Hip and Knee Arthroplasty
The intent of this study is to evaluate the Prevena ™ 125 Unit and dressing system, when applied to either the hip or knee area over a surgical cut for the time you are hospitalized.
- Conditions
- Linear or Emi-linear Incisions, Total Hip Arthroplasty, Total Knee Arthroplasty
- Trial name
- Prevena2009-45 (NCT01380665)
- Testing
- Prevena Incisional Management System
- Sponsor
- KCI USA, Inc
Arthroplasty
A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain After Hip Replacement Surgery Compared With Oxycodone and Placebo Followed by a Voluntary Open-Label Extension For Safety
The purpose of this study is to test in patients who have had hip replacement surgery the effectiveness (level of pain control) and the safety of 3 different dose levels of CG5503 compared with placebo and with 10-mg oxycodone…
- Trial name
- NCT00364533
- Testing
- Tapentadol IR (CG5503), Oxycodone HCL IR
- Where
- 77 sites in United States, Belgium and 6 more
- Volunteers
- 367 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Osteoarthritis, Post-traumatic Arthritis
A Randomised Multi-centre Study to Compare the Long-term Performance of the Future Hip to 3 Other Implants in Primary Total Hip Replacement
This post-market clinical follow-up study was designed to compare hip replacement outcomes of the European Hip against 3 controls (Omniflex, Zweymuller, and Spotorno), however Omniflex did not end up being used.
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders, Avascular Necrosis
- Trial name
- NCT00208468
- Testing
- European Hip, Zweymüller, CLS Spotorno
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 317 people
- Sponsor
- DePuy International
Total Hip Replacement, Total Knee Replacement
An Open Label Data Collection Study of My Connect Post-Op, a Post-Operative Communication Tool
This open label, multi-center study will collect data from the participant's use of My Connect Post-Op Software as a post-operative communication solution in supporting patient recovery through Technology-Assisted Conversation…
- Trial name
- NCT07120191
- Testing
- post op communication software
- Where
- 3 sites in United States
- Volunteers
- 652 people
- Sponsor
- Concentra AI, inc
Arthroplasty, Replacement, Hip
Pelvic Alignment Level (PAL) Instrument Evaluation
The study is conducted to evaluate the performance of the Pelvic Alignment Level (PAL) instrument in achieving desired acetabular position, desired leg length and offset after Total Hip Replacement (THR) reconstruction.
- Trial name
- PAL (NCT01312428)
- Testing
- Pelvic Alignment Level (PAL) Instrument, No Pelvic Alignment Level (PAL) Instrument
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Stryker Orthopaedics
Total Knee Arthroplasty; Total Hip Arthroplasty
Health Partner Evaluation at Princeton
This is a prospective, single-center, randomized, comparative, controlled study. Penn Medicine Princeton Medical Center will enroll a total of 296 subjects (18 years or older) who are electing to have total knee or hip…
- Trial name
- NCT03386786
- Testing
- Health Partner, Standard Care
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- DePuy Orthopaedics
Hip Arthropathy
Observational Ambispective Study on HYPE Cups Associated With HIPER Liner
This study intend to collect data on total hip arthroplasty performed with HYPE cups used with conventional polyethylene liner (HIPER).
- Trial name
- NCT06465940
- Testing
- Total hip arthroplasty
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Societe dEtude, de Recherche et de Fabrication