Clinical trials: Total Hip Arthroplasty
Bone Loss
Can Risedronate Prevent Periprosthetic Bone Loss After Total Hip Arthroplasty
Can risedronate given once weekly for 6 months prevent periprosthetic bone loss after uncemented total hip arthroplasty?
- Trial name
- PREVENT (NCT00772395)
- Testing
- Risedronate
- Where
- Sweden
- Volunteers
- 78 people
- Sponsor
- Danderyd Hospital
THA
Fascia Iliaca Blocks for Total Hip Arthroplasty
The development of minimal-incision techniques for total hip arthroplasty (THA) with preservation of soft tissue is generally associated with reduction of postoperative pain and increased patient comfort.
- Trial name
- NCT03691337
- Testing
- Marcaine 0.25 % Injectable Solution, Sodium chloride
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- New York School of Regional Anesthesia
Hip Osteoarthritis
OXINIUM◊ DH Total Hip Arthroplasty Pivotal Study
The purpose of this study is to monitor safety of the participants implanted with the OXINIUM◊ DH Hip System up to 10-years post-implantation
- Trial name
- NCT02353377
- Testing
- OXINIUM DH Hip System, BIOLOX◊
- Volunteers
- 413 people
- Sponsor
- Smith & Nephew, Inc.
Anesthesia, Post Operative Pain
Volume Effect in Peng Block for Total Hip Replacement
This study is to investigate whether a different volume of ropivacaine, with the same prescribed dosage based on body weight, can affect block efficacy, duration and side effects in the first 24 hours postoperatively.
- Trial name
- volupeng (NCT06427551)
- Testing
- Ropivacaine
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Total Knee Replacement, Total Hip Replacement
New Oral Anticoagulant Therapy for the Prevention of Blood Clots Following Hip or Knee Replacement Surgery
LY517717 (a capsule given by mouth) is a blood thinner that may prevent blood clots from forming in the legs and may prevent those blood clots from traveling to the lungs.
- Trial name
- NCT00074828
- Testing
- LY517717, enoxaparin
- Where
- 8 sites in Australia, Austria and 6 more
- Volunteers
- 511 people
- Sponsor
- Eli Lilly and Company
Osteoarthritis, Hip
Mini Stem DEXA (Dual Energy X-ray Absorptiometry)
The objective of this study is to evaluate the bone ingrowth after implantation of the study device. This study will also document any device-related surgical complications or adverse radiographic observations.
- Trial name
- MISDexa (NCT01066936)
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Smith & Nephew, Inc.
Total Hip Arthroplasty, Osteoarthritis, Hip
Dual-mobility Cups Compared to Unipolar Cups on Dislocation and Cost-effectiveness After Primary Total Hip Arthroplasty.
Objective: The primary objective is to investigate whether there is a difference in the number of hip dislocations following primary total hip arthroplasty (THA), using the posterolateral approach, with a DM cup compared to a…
- Trial name
- REDEP (NCT04031820)
- Testing
- Unipolar cup, Dual mobility cup
- Where
- Netherlands
- Volunteers
- 1,100 people
- Sponsor
- JointResearch
Hip, Osteoarthritis
H-34 DELTA Revision Cup
THis study is aimed to provide a clinical and radiographic evaluation of 49 suitable subjects who underwent a total hip arthroplasty with DELTA Revision acetabular cup.
- Trial name
- NCT06359301
- Testing
- DELTA Revision acetabular cup
- Where
- Poland
- Volunteers
- 49 people
- Sponsor
- Limacorporate S.p.a
Total Hip Arthroplasty, The Analgesic Efficacy
The Analgesic Efficacy of Oxycodone Hydrochloride Versus Fentanyl After Total Hip Arthroplasty:
Oxycodone showed similar or superior analgesic effects than fentanyl and was proposed as an alternative for fentanyl for pain control in the postoperative period.
- Trial name
- NCT05602519
- Testing
- propofol, rocuronium and fentanyl
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Al-Azhar University
Regional Anesthesia Morbidity, Arthropathy of Hip
PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis
Background: Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation.
- Conditions
- Regional Anesthesia Morbidity, Arthropathy of Hip, Hip Arthropathy
- Trial name
- PENG+LFCN-FICB (NCT05916209)
- Testing
- Peripheral nerve blocks
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Ospedale Edoardo Bassini
Osteoarthritis, Vitamin D Deficiency
Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA)
The purpose of this study is being conducted to determine whether correcting low levels of vitamin D with a single high-dose supplement reduces complications after the participant's primary TJA.
- Trial name
- NCT07006714
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Miami
Total Knee Replacement
Continuous Postoperative Pulse Oximetry in Patients Presenting for Total Hip and Total Knee Replacement
The purpose of this study is to evaluate the incidence of low levels of oxygen as determined by standard pulse oximetry monitor in patients who have had total hip or knee replacement/revision.
- Trial name
- NCT01189565
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Adverse Local Tissue Reaction, Total Hip Arthroplasty
ASR-XL Metal-on-Metal 522 Post-Market Surveillance Study
The purpose of this clinical study is to evaluate blood metal ion levels as a function of time of implantation for the ASR-XL MoM system.
- Trial name
- NCT01884532
- Testing
- ASR-XL Metal-on-Metal
- Where
- 7 sites in United States
- Volunteers
- 146 people
- Sponsor
- DePuy Orthopaedics
Arthroplasty, Osteoarthritis
Efficacy of Preoperative Muscle Training on Postoperative Orthopaedic Surgery Recovery
The purpose of this study is to assess the effectiveness of a preoperative muscle training program on hip or knee TJA (Total Joint Arthroplasty).
- Trial name
- NCT03483519
- Testing
- Rehabilitation, Standard of Care
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Ottawa Hospital Research Institute
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
Ceramic-on-Ceramic (COC) 36mm Acetabular Bearing Insert Post Approval Study-New Subjects (COC36mmPAS)
This study is intended to gather short (Pre-operative to 4-years) and mid-term (5-years) information regarding the performance and safety of the commercially available 36mm CERAMAX® Ceramic on Ceramic Total Hip System from a…
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-Traumatic Osteoarthritis of Hip
- Trial name
- COC36mmPAS (NCT02096211)
- Testing
- COC 36mm
- Where
- 13 sites in United States, Canada
- Volunteers
- 172 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis
Accelerated Rehabilitation in Hip Arthroplasty
Accelerated rehabilitation protocol in Total Hip Arthroplasty (THA-AR).
- Trial name
- ARTHA (NCT02933632)
- Testing
- Physical Therapy-SAP, Physical Therapy-ARP
- Where
- 2 sites in Brazil
- Volunteers
- 48 people
- Sponsor
- Federal University of Rio Grande do Sul
Osteoarthritis of Hip
Investigation to Determine Safety of Taperloc Stems With BioGuard Coating When Used in Cementless Total Hip Arthroplasty
Prospective clinical investigation to determine the safety of Taperloc stems with BioGuard coating and Exceed ABT Taperfit acetabular cups with BioGuard coating when used in cementless total hip arthroplasty
- Trial name
- NCT02263209
- Testing
- Bioguard Group, Control Group
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Osteoarthrosis
Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients
The study evaluates the pathophysiological effects of a single dose Methylprednisolone administered prior to total hip-arthroplasty (THA) surgery.
- Trial name
- NCT02445898
- Testing
- Methylprednisolone, Isotonic Sodium Chloride
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Delirium, Hip Arthroplasty
Delirium, Intraoperative Cerebral Perfusion and EEG Abnormalities After Total Hip Arthroplasty
The overall objective of this study is to test for perturbations in intraoperative electroencephalogram (EEG) , cerebral blood flow (CBF), cerebral metabolic rate of oxygen consumption (CMRO2), oxygen extraction fraction (OEF)…
- Conditions
- Delirium, Hip Arthroplasty, Elderly
- Trial name
- NCT02818764
- Testing
- Blood Draw, Cerebral Spinal Fluid collection, Electroencephalogram
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Pennsylvania
Pain
Psoas Compartment Block Versus Fascia Iliaca Block After Total Hip Arthroplasty
A psoas compartment block has been used with good results for postoperative pain relief after total hip arthroplasty (THA). However, case reports describing serious complications after the use of this block, have been reported.
- Trial name
- NCT01378949
- Testing
- Bupivacaine, Morphine
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Hillel Yaffe Medical Center
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