Clinical trials: Total Hip Arthroplasty (THA)
Hip Replacement
Patient Outcomes Using HIP7 Software as Compared to Conventional THA
The study is designed to demonstrate how Hip7 software can lead to improved patient outcomes compared to conventional procedures with standard instrumentation for total hip arthroplasties (THA) surgery.
- Trial name
- NCT04989998
- Testing
- Hip7 Software on Kick/ CORI platforms, Conventional surgical procedures
- Sponsor
- Smith & Nephew Orthopaedics AG
Primary Total Hip Arthroplasty
Total Hip Arthroplasty (THA): Early Load Versus Load Late
In Brazil, several hip surgeries performed, especially total knee arthroplasty, which represents 1.5 million procedures (Penedo, New, 2007).
- Trial name
- Latearly (NCT01495546)
- Testing
- Early loading, Late loading
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo
Total Hip Arthroplasty (THA)
Impact of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Elective Hip Replacement
In the present project, the framework conditions of outpatient rehabilitation at the Bonn Center for Outpatient Rehabilitation will now be used to prove whether sports science-controlled strength and BFR training has a similar…
- Trial name
- NCT07043127
- Testing
- BFR
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Hip and Knee Osteoarthritis
Recovery After Fast Track THA / TKA
The development and implementation of "fast-track" principles in total knee and hip arthroplasty have resulted in early recovery and rehabilitation alongside a reduced length of hospital stay.
- Trial name
- 0-21 (NCT02137655)
- Where
- 2 sites in Denmark
- Volunteers
- 112 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Total Hip Arthroplasty (THA)
A Safety Follow Up Study in Australian Subjects Implanted With the SMF Short Modular Femoral Stem Hip System
This is a prospective, single arm, sequential enrolment study to collect relevant clinical and radiological data in approximately 26 subjects, at one site in Australia, who have been implanted with the SMF Short Modular Femoral…
- Trial name
- NCT03646513
- Testing
- SMF Short Modular Femoral Hip System
- Where
- Australia
- Volunteers
- 4 people
- Sponsor
- Smith & Nephew, Inc.
Coxarthrosis
Compaction Total Hip Arthroplasty (THA) Bilateral
This is a prospective, randomized study comparing two different bone preparation techniques for insertion of a porous coated titanium cementless femoral stem.
- Trial name
- NCT00317889
- Testing
- Bone preparation technique: compaction, Bone preparation technique: broaching
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Pain After Abdominal Surgery
A Clinical Trial Evaluating the Efficacy and Safety of Local Infiltration of RF16001 for Injection for Analgesia After Total Hip Arthroplasty in China
A multicenter, randomized, double-blind, placebo-positive, parallel-controlled, phase Ⅲ clinical trial was conducted to investigate the efficacy and safety of RF16001 local infiltration for analgesia after total hip arthroplasty.
- Trial name
- NCT07872826
- Testing
- RF16001 for injection, Ropivacaine hydrochloride injection, 0.9% sodium chloride injection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Dislocation, Total Hip Arthroplasty
Preoperative Gluteal Muscle Atrophy: A Silent Predictor of THA Dislocation.
This study looks at how fat buildup in hip muscles relates to hip osteoarthritis and less favorable recovery after hip replacement surgery.
- Conditions
- Dislocation, Total Hip Arthroplasty, Muscle Degeneration
- Trial name
- NCT06571604
- Testing
- Dislocation, No dislocation
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
THA, Dislocation, Hip
The Q-REDUCE Study
The purpose of this study is to design a fast-track pathway for patients referred to the University Hospital of Southern Denmark, Esbjerg, with high probability of having a dislocated hip prosthesis with the primary aim to reduce…
- Conditions
- THA, Dislocation, Hip, PROM
- Trial name
- NCT06639334
- Testing
- Fasttrack pathway for THA/HE prosthesis reduction, Standard pathway for THA/HE prosthesis reduction
- Volunteers
- 120 people
- Sponsor
- University of Southern Denmark
Osteoarthritis, Hip
KINCISE™ Surgical Automated System in Total Hip Arthroplasty (THA)
There is a growing interest in the effects of mental health and wellness on orthopedic intervention outcomes, not only in terms of how advances in surgical procedures influence patient outcomes, but also with regard for physician…
- Trial name
- NCT05223777
- Testing
- KINCISE, Traditional Handheld Mallet
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Cincinnati
THA
Duloxetine for Perioperative Pain in Hip Arthroplasty: A RCT
The primary objective of this study is to compare total narcotic intake standardized via milligram morphine equivalents between duloxetine and placebo cohorts after a total hip arthroplasty.
- Trial name
- NCT06807866
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Miami
Osteoarthritis (OA) of the Hip
Gait After THA: Direct Anterior vs Manual Posterior vs Robotic Posterior
The purpose of this study is to evaluate the gait biomechanics following THA on 3 groups of subjects undergoing DAA (manual) and PA (manual and robotic) surgical approaches.
- Trial name
- NCT07226973
- Testing
- Total hip arthroplasty via direct anterior approach (manual, non-robotic), Total hip arthroplasty via posterior approach (manual, non-robotic), Robotic-assisted total hip arthroplasty via posterior approach
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Ochsner Health System
Arthropathy of Hip, Arthropathy of Knee
Evaluation of Weight Bearing After Total Hip and Knee Replacement
The regime in the aftercare after total hip and knee arthroplasty(THA/TKA) differs a lot between orthopedic surgeons concerning weight bearing. The type of implant and the way of implants' anchoring are considered.
- Trial name
- NCT01135160
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Kantonsspital Münsterlingen
Total Hip Arthroplasty, Muscle Injury
Safety and Efficacy of IM Injections of PLX-PAD for the Regeneration of Injured Gluteal Musculature After Total Hip Arthroplasty
Local administration of PLX-PAD single dose, intra-muscular injection for the regeneration of injured gluteal musculature after Total Hip Arthroplasty (THA).
- Trial name
- NCT01525667
- Testing
- 150M PLX-PAD, 300M PLX-PAD
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Pluristem Ltd.
Osteoarthritis
PT vs no PT Following THA
The purpose of this study is to determine if outpatient physiotherapy results in improved and/or more rapid achievement of functional outcomes and quality of life in comparison to those patients who do not undergo outpatient…
- Trial name
- NCT02687945
- Testing
- Outpatient physiotherapy, Self-guided physiotherapy
- Sponsor
- Rothman Institute Orthopaedics
Osteoarthritis, Hip, Joint Deformities, Acquired
Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty
The purpose of this study is to establish whether or not there is a clinical advantage to the use of Aquamantys® System from Medtronic Advanced Energy (formerly Salient Surgical Technologies) in patients undergoing primary total…
- Conditions
- Osteoarthritis, Hip, Joint Deformities, Acquired, Hip Dislocation, Congenital, Osteonecrosis
- Trial name
- Aquamantys (NCT01583465)
- Testing
- Aquamantys, standard electrocautery (Bovie)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Joint Implant Surgeons, Inc.
Direct Anterior Total Hip Arthroplasty
Direct Anterior Total Hip Arthroplasty (THA), in Versus Outpatients : A Prospective Monocentric Study in Rennes University Hospital.
The main objective is to show that cumulative length of stay over the first 45 post operative days (i.e. : primary length of stay and readmission) is significantly lower in the outpatients group than in the inpatients group
- Trial name
- AHVACA (NCT03667339)
- Testing
- Direct Anterior Total Hip Arthroplasty
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Rennes University Hospital
Degenerative Joint Disease, Osteoarthritis
Epsilon Aminocaproic Acid (EACA) for the Reduction of Blood Loss in Total Hip Arthroplasty (THA)
You are being asked to take part in this research study because you are scheduled to have total hip replacement (arthroplasty) surgery.
- Trial name
- NCT01391182
- Testing
- EACA
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hip Osteoarthritis
Effect of an Alumina Free Device Surface on BMD in Patients Implanted With an SL-PLUS™ Femoral Stem for THA
Alumina particles from the grit blasting of Ti-alloy stems for hip arthroplasty are suspected to contribute to aseptic loosening.
- Trial name
- NCT05053048
- Testing
- SL-PLUS-Stem for total hip arthroplasty
- Volunteers
- 45 people
- Sponsor
- Kantonsspital Baselland Bruderholz
Postoperative Pain, Total Hip Arthroplasty (THA)
Safety and Efficacy of Dexamethasone Versus Dexmedetomidine as Adjuvants in PENG Block in Hip Surgeries for Postoperative Pain Management
This study evaluates and compares the analgesic efficacy and safety of adding dexamethasone versus dexmedetomidine to bupivacaine in an ultrasound-guided pericapsular nerve group (PENG) block combined with a lateral femoral…
- Trial name
- NCT07847047
- Testing
- Bupivacaine 0.25%, Dexamethasone, Dexmedetomidine
- Volunteers
- 90 people
- Sponsor
- Assiut University