Clinical trials: Total Hip Replacement Arthroplasty
Coxarthritis
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Corail Prosthesis With or Without Collar Design
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Corail prosthesis with or without collar design. Randomized study design focusing on radiolucent lines on standard x-ray.
- Trial name
- NCT02960633
- Testing
- Corail with collar., Corail without collar.
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ZOL
Hyperglycemia
Metformin Use in Patients Undergoing Total Joint Replacement Surgery
The goal of this pilot, randomized, single-blind, placebo-controlled trial is to evaluate the feasibility of and provide preliminary information for a multi-center randomized controlled trial that will assess the effects of…
- Trial name
- NCT06280274
- Testing
- Metformin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Coxarthrosis
Compaction Femur Preparation for Cementless Total Hip Arthroplasty (THA) Unilateral
This is a prospective, randomized study comparing two different bone preparation techniques for insertion of a hydroxylapatite (HA) coated titanium cementless femoral stem.
- Trial name
- NCT00318396
- Testing
- Bone preparation technique: compaction, Bone preparation technique: conventional technique
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Prosthetic Joint Infection, Vancomycin
Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol
The objective of this study is to evaluate a novel vancomycin intraosseous administration protocol vs a standard IV vancomycin administration protocol for primary total hip arthroplasty patients.
- Conditions
- Prosthetic Joint Infection, Vancomycin, Joint Diseases
- Trial name
- NCT04042233
- Testing
- Experimental Intraosseous vancomycin 500mg in 250 mL NS, Standard IV administration of vancomycin
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- The Methodist Hospital Research Institute
Bursa; Tuberculous, Hip Bursitis
Trochanteric Bursal Repair After a Total Hip Replacement - Are There Benefits During the First 90 Days
During total hip arthroplasty surgery, the trochanteric bursa is routinely excised. This anatomical structure, which functions as a soft tissue barrier, is generally recommended for removal as it facilitates the surgical…
- Conditions
- Bursa; Tuberculous, Hip Bursitis, Deep Gluteal Syndrome, Hip Disease
- Trial name
- NCT06553508
- Testing
- Trochanteric bursa repaired, Trochanteric bursa unrepaired
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Ankara City Hospital Bilkent
Arthroplasty, Recovery of Function
The Influence of Rapid Recovery on Sleep Quality Following Total Hip Replacement Surgery
To evaluate the influence of rapid recovery on sleep quality following total hip replacement surgery
- Conditions
- Arthroplasty, Recovery of Function, Sleep Quality
- Trial name
- NCT02852460
- Testing
- rapid recovery
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Southwest Hospital, China
Hip Fractures, Femoral Neck Fractures
Comparing Total Hip Arthroplasty and Hemi-Arthroplasty on Secondary Procedures and Quality of Life in Adults With Displaced Hip Fractures
Each year, hip fracture, an injury that can impair independence and quality of life, occurs in about 280,000 Americans and 36,000 Canadians.
- Trial name
- HEALTH (NCT00556842)
- Testing
- Total hip arthroplasty, Hemi-arthroplasty
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,495 people
- Sponsor
- McMaster University
Acetabular Fracture
RCT Determining Best Treatment for Geriatric Acetabular Fractures
There is debate over the best management for acetabular (hip) fractures that occur within the geriatric population. Geriatric patients, 60 years or older, are at greater risk for operative complications because they tend to have…
- Trial name
- GeriTab (NCT03419182)
- Testing
- Open Reduction internal Fixation, Open Reduction Internal Fixation with Total Hip Arthroscopy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Maryland, Baltimore
Wound Healing Time, Total Hip Arthroplasty (THA)
Wound Healing, Dressing Type, and Dressing Change Frequency in THA
Surgical wound complications following primary total hip arthroplasty remain a significant clinical challenge despite advances in wound care technologies.
- Trial name
- CAP-HIP (NCT07655388)
- Testing
- VACUTEX™ wound dressing, Octenisept® wound care dressing
- Where
- Serbia
- Volunteers
- 90 people
- Sponsor
- Clinical Center of Vojvodina
Pain, Postoperative
Oxycodone vs. Fentanyl in Early Postoperative Pain After Total Hip Replacement
Oxycodone is one of the most widely used opioids for pain treatment. Many studies demonstrated good efficacy of oxycodone on postoperative pain.
- Trial name
- NCT03019562
- Testing
- Oxycodone, Fentanyl
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Kyunghee University Medical Center
Postoperative Pain, Regional Anesthesia
Comparison of Continuous Fascia Iliaca Compartment Block With Continuous PENG Block in Total Hip Replacement Cases
Adequate pain management after total hip arthroplasty (THA) is crucial for early ambulation and patient satisfaction. However, due to the hip joint's innervation complexity, the optimal regional analgesia technique for THA…
- Conditions
- Postoperative Pain, Regional Anesthesia, Pain Management, Total Hip Arthroplasty
- Trial name
- PENG (NCT06806865)
- Testing
- Periarticular nerve group block (PENG), Continuous supra-inguinal fascia iliaca compartment block (SIFICB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Osteoarthritis, Hip
Unrestricted Rehabilitation Following Primary THA
The purpose of this study is to determine whether the form of rehabilitation following primary total hip arthroplasty has an influence on patient satisfaction or functional performance in the eighteen weeks following surgery.
- Trial name
- NCT02079467
- Testing
- Unrestricted rehabilitation, Standard rehabilitation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Total Hip Arthroplasty
Two Different Administration Methods of Tranexamic Acid on Perioperative Blood Loss During Total Hip Arthroplasty
To compare the two administration methods of tranexamic acid for patients undergoing the first unilateral THA, to explore the effects of tranexamic acid on perioperative blood loss from the aspects of dominant blood loss, hidden…
- Trial name
- NCT03157401
- Testing
- intravenous infusion group, intra-articular injection group, control group
- Volunteers
- 90 people
- Sponsor
- Tengzhou Central People's Hospital
Arthritis
Real Time 3D Imaging and Surrogate Bone Model
This is an observer-blinded prospective randomized clinical trial to define the efficacy of a new technology developed at the Cleveland Clinic to improve the positioning of the acetabular shell in total hip arthroplasty.The…
- Trial name
- NCT02204007
- Testing
- 3D imaging & surrogate bone model
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Arthroplasty Complications, Analgetic
Preemptive Analgesia Combination of Celecoxib and Pregabalin in THA
This is a double-blinded randomized controlled trial aims to evaluate the effect of preemptive analgetic combination of celecoxib and pregabalin to acute pain after total hip arthroplasty.
- Conditions
- Arthroplasty Complications, Analgetic, Celecoxib, Pregabalin
- Trial name
- NCT05509946
- Testing
- Single dose of celecoxib 400 mg and pregabalin 150 mg, Repeated dose of celecoxib 200 mg and pregabalin 75 mg
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Total Hip Arthroplasty
Closed Suction Drain or Not After Total Hip Arthroplasty
Comparative randomised study to clarify which better to use or no use of closed suction drain system after total hip arthroplasty regarding amount of blood loss, need for blood transfusion, risk for superficial infection…
- Trial name
- NCT02845427
- Testing
- closed suction drain, no suction drain
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Osteoarthritis, Hip, Rheumatoid Arthritis
Exception Cementless Hip Stem
This study is a multicenter, retrospective and prospective, non-controlled, non-randomized post market clinical follow-up study.
- Conditions
- Osteoarthritis, Hip, Rheumatoid Arthritis, Inflammatory Arthritis, Congenital Hip Dysplasia
- Trial name
- Exception (NCT04349046)
- Testing
- Total hip arthoplasty (THA)
- Where
- 6 sites in Belgium, France
- Volunteers
- 332 people
- Sponsor
- Zimmer Biomet
Arthroplasty, Replacement, Hip, Blood Transfusion
Comparison in Need for Bank Blood Between Patients Undergoing Total Hip Surgery That Either Receive Their Own Blood Back or Not
The study is a prospective, controlled, randomised and assessor blind study that investigate if the need for bank blood transfusion could be reduced in patients, undergoing primary or revision total hip replacement surgery, who…
- Conditions
- Arthroplasty, Replacement, Hip, Blood Transfusion, Blood Transfusion, Autologous
- Trial name
- NCT00822588
- Testing
- Sangvia® System
- Where
- 6 sites in Austria, Netherlands and 2 more
- Volunteers
- 227 people
- Sponsor
- Wellspect HealthCare
Total Hip Replacement
The Effect of Mandala Art Therapy on Anxiety and Pain
This study aims to evaluate the effects of mandala art therapy on anxiety and pain in patients undergoing total hip replacement.
- Trial name
- NCT06628557
- Testing
- The Effect of Mandala Art Therapy on Anxiety and Pain in Patients
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Seval Ulubay
Total Hip Replacement
Randomized Clinical Trial of Ceramic Bearing Primary Total Hip Arthroplasty
Primary total hip arthroplasty (THA) has been a very successful surgical intervention in the geriatric population. Numerous studies have reported good mid and long term results of THA in patients over the age of 60 years.
- Trial name
- NCT01522014
- Testing
- Secure-Fit™ arc-deposited Hydroxylapatite (HA) shell - surface ceramic and an Alumina Bearing Couple (ABC) ceramic insert and Ceramic C-taper head, Secure-Fit™ arc-deposited hydroxylapatite shell, a Crossfire® insert and a Ceramic C-taper head
- Where
- 2 sites in Canada
- Volunteers
- 92 people
- Sponsor
- University of Alberta
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