Clinical trials: Total Hip Replacements
Prosthesis-Related Infections
Oral Antibiotics After 2-Stage Revision for Infected Total Hip Arthroplasty and Total Knee Arthroplasty
The primary purpose of this study is to compare the re-infection rates in patients undergoing 2-stage revision arthroplasty who receive additional oral antibiotic therapy to those patients who received in-hospital perioperative…
- Trial name
- NCT01760863
- Testing
- Oral Antibiotics
- Where
- 4 sites in United States
- Volunteers
- 185 people
- Sponsor
- Rush University Medical Center
Femoral Neck Fractures, Osteoporosis
Complications and Functional Outcome of Displaced Femoral Neck Fractures in Patients Younger Than 70 Years
Patients younger than 70 years with a displaced femoral neck are in serious conditions. The femoral neck fracture is associated with low activity levels, hip pain and substantially reduced quality of life.
- Trial name
- NCT02085707
- Testing
- Total hip replacement arthroplasty, Closed reduction and internal fixation
- Where
- 4 sites in Norway
- Volunteers
- 118 people
- Sponsor
- University Hospital, Akershus
Non-inflammatory Joint Disease, Osteoarthritis
Post-approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System
This study is being conducted to gather medium and long-term information regarding the performance and safety of the commercially available DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System.
- Conditions
- Non-inflammatory Joint Disease, Osteoarthritis, Avascular Necrosis, Congenital Hip Dysplasia
- Trial name
- NCT00546598
- Testing
- Total hip replacement/arthroplasty
- Where
- 6 sites in United States
- Volunteers
- 106 people
- Sponsor
- DePuy Orthopaedics
Hip Arthroplasty Replacement, Hip Arthroplasty, Total
Health-GIS Platform for Hip Replacement Rehabilitation Coordination
This study tests whether a mobile phone app with mapping technology can help patients find rehabilitation services faster after hip replacement surgery.
- Conditions
- Hip Arthroplasty Replacement, Hip Arthroplasty, Total, Rehabilitation, Hip Osteoarthritis
- Trial name
- NCT07201116
- Testing
- Health-GIS Rehabilitation Coordination Platform, Standard Rehabilitation Referral
- Where
- Kazakhstan
- Volunteers
- 142 people
- Sponsor
- Tulip Medicine
Total Hip Arthroplasty
Rehabilitation After Direct Anterior Approach for Total Hip Arthroplasty
The causes for total hip arthroplasty (THA) in Taiwan include ischemic necrosis of the femoral head and degenerative osteoarthritis.
- Trial name
- NCT06356116
- Testing
- Usual care, Accelerated rehabilitation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Postoperative Anemia, Arthroplasty, Replacement, Hip
Phase IIa Trial of Oral SSS17 for Post-Arthroplasty Anemia
To assess the safety, tolerability, efficacy, and pharmacokinetic/pharmacodynamic (PK/PD) characteristics of orally administered SSS17 capsules in patients with postoperative anemia following elective total hip or knee…
- Conditions
- Postoperative Anemia, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT07007936
- Testing
- SSS17 Capsule (6 Dose Levels)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shenyang Sunshine Pharmaceutical Co., LTD.
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up
The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (>60y) after total hip or knee replacement surgery.
- Trial name
- NCT01103752
- Testing
- no intervention, descriptive study
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Lene Krenk
Osteoarthritis, Hip, Femur Head Necrosis
Clinical Outcomes of Primary Cementless Total Hip Arthroplasty Using the Collarless Actis Stem
This study looks at how well a hip replacement using the collarless Actis stem works over five years. Total hip replacement is a common operation for people whose hip joint has been damaged by arthritis, by loss of blood supply…
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Femoral Neck Fractures, Arthritis Rheumatoid
- Trial name
- NCT07828080
- Testing
- Collarless Actis femoral stem
- Where
- South Korea
- Volunteers
- 210 people
- Sponsor
- Seoul National University Bundang Hospital
Hyperglycemia
Metformin Use in Patients Undergoing Total Joint Replacement Surgery
The goal of this pilot, randomized, single-blind, placebo-controlled trial is to evaluate the feasibility of and provide preliminary information for a multi-center randomized controlled trial that will assess the effects of…
- Trial name
- NCT06280274
- Testing
- Metformin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Osteoarthritis, Hip
Early Virtual Reality Based Home Rehabilitation Program After Total Hip Arthroplasty
Total hip replacement (THR) is one of the most common interventions in orthopedic surgery. Rehabilitation is essential for maximizing the effectiveness of the surgery.
- Trial name
- NCT04221425
- Testing
- virtual reality rehabilitation system (VRRS), standard care
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Pain, Postoperative
Combination Effects of Pregabalin and Dexmedetomidine on Postoperative Pain
Pregabalin and dexmedetomidine have been introduced to manage postoperative pain. The present study aimed to evaluate the effect of the combination of two drugs on pain relief in patients undergoing total knee or hip arthroplasty…
- Trial name
- NCT03512574
- Testing
- Pregabalin, Dexmedetomidine, Pregabalin and dexmedetomidine
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Osteoarthritis, Arthroplasty Complications
Varus Stem Positioning of a Cementless Anatomical THA. (VARABG)
Varus positioning is the most common femoral malposition in total hip arthroplasty (THA). The aim of this study was to compare the long-term results of an anatomical cementless femoral stem positioned in varus with those in…
- Trial name
- VARABG (NCT04653090)
- Testing
- Xray
- Where
- France
- Volunteers
- 283 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Total Hip Arthroplasty, Postoperative Pain
PENG Block vs Intrathecal Morphine in Total Hip Arthroplasty
To compare the impact of pericapsular nerve group (PENG) block to intrathecal morphine on postoperative analgesia, motor function and side effects in patients undergoing primary total hip arthroplasty under spinal anesthesia.
- Trial name
- NCT05308420
- Testing
- Pericapsular nerve group (PENG) block, Spinal anesthesia, Intrathecal morphine
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Kresimir Oremus, MD
Osteoarthritis
Importance of Restoring Biomechanical Correct Hip Anatomy During Total Hip Arthroplasty
The purpose of this prospective, randomized study is to evaluate the importance of restoring the exact individual hip biomechanics during total hip arthroplasty.
- Trial name
- NCT01512550
- Testing
- GF hip guide, Stryker Navigation System, ABG II modular femoral component
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Region Skane
Osteoarthritis, Total Hip Arthroplasty
Predictability of the Ability to Perform an Emergency Stop With Disorders of the Hip
Several studies exist on patient performance in drive simulators especially around and after surgery. Recommendations concerning the ability to drive preoperatively are based on these studies, which generated their data using…
- Trial name
- NCT02308813
- Testing
- Braking and functionality
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Postoperative Pain, Hip Arthroplasty
Multihole or Epidural Catheter for Local Anesthetic in the Wound
Postoperative administration of local anesthetics is effective for postoperative pain management across surgical specialties but the optimal type of catheter (single, few or multiholed catheters) has not been determined.
- Trial name
- NCT00921908
- Testing
- 2 mBq radioactive technetium diluted in 20 mL saline
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Hvidovre University Hospital
Hip Implant, Hip Replacement in Osteoarthritis Patients
Radiographic Migration Analysis of the Insignia Hip Stem
The purpose of this study is to assess the migration pattern of the Insignia hip stem using radiostereometric analysis (RSA for short) and computed tomography (CT).
- Conditions
- Hip Implant, Hip Replacement in Osteoarthritis Patients, Migration of Implant
- Trial name
- NCT06696313
- Testing
- Insignia
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Canadian Radiostereometric Analysis Network
Total Hip Arthroplasty (THA)
Comparing Outcomes of Labrum Preservation vs Excision in Primary Total Hip Arthroplasty
This research is being done to determine whether removing or preserving the acetabular labrum, a ring of cartilage around the hip socket, during hip replacement surgery affects post-operative outcomes, operative time, or ease of…
- Trial name
- NCT07812025
- Testing
- Labrum Preservation, Labrum Excision
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Total Joint Specialists
Acute Pain
Oral Treatment for Orthopaedic Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride
This study aims to evaluate the analgesic efficacy of single and repeated doses of fixed combination of dexketoprofen trometamol (DKP) and tramadol hydrochloride (TRAM) in comparison to the single agents (and placebo for the…
- Trial name
- DAVID-art (NCT01902134)
- Testing
- Tramadol-single dose, Dexketoprofen-single dose, Dexketoprofen/Tramadol-single dose
- Where
- 37 sites in Czechia, Germany and 8 more
- Volunteers
- 641 people
- Sponsor
- Menarini Group