Clinical trials: Total Hip Surgery
Venous Thromboembolism
Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Hip Replacement Surgery
The purpose of this study is to examine the superiority of YM150 to the placebo and to evaluate the dose-dependent response of YM150 in patients undergoing elective total hip replacement surgery.
- Trial name
- NCT00913120
- Testing
- YM150, Enoxaparin
- Where
- 16 sites in Japan, South Korea and 2 more
- Volunteers
- 610 people
- Sponsor
- Astellas Pharma Inc
Postoperative Pain, Total Hip Arthroplasty (THA)
Safety and Efficacy of Dexamethasone Versus Dexmedetomidine as Adjuvants in PENG Block in Hip Surgeries for Postoperative Pain Management
This study evaluates and compares the analgesic efficacy and safety of adding dexamethasone versus dexmedetomidine to bupivacaine in an ultrasound-guided pericapsular nerve group (PENG) block combined with a lateral femoral…
- Trial name
- NCT07847047
- Testing
- Bupivacaine 0.25%, Dexamethasone, Dexmedetomidine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Osteoarthritis
Inpatient vs Outpatient Total Hip Replacement
This study is a pragmatic randomized clinical trial comparing standard inpatient total hip arthroplasty with same day discharge.
- Trial name
- NCT03026764
- Testing
- Outpatient, Inpatient
- Where
- Canada
- Volunteers
- 558 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hip Arthroplasty
Stem Cells Predicting Orthopedic Outcomes
This is a pilot study to provide preliminary data of the association between bone mineral denity adjacent to acetabular implants, as measured by quanitative computed tomography (QCT), at least 2 years post Total Hip Arthoplasty…
- Trial name
- NCT01366911
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Coagulation; Intravascular, Rotational Thromboelastometry
The Effect of Tranexamic Acid on Blood Coagulation in Total Hip Arthroplasty Surgery
Total hip arthroplasty (THA) is associated with blood loss ranging from 300 to 2000 mL. Tranexamic acid (TXA) is frequently administered prophylactically during this procedure to reduce blood loss by inhibiting fibrinolysis or by…
- Conditions
- Coagulation; Intravascular, Rotational Thromboelastometry, Fibrinolysis; Hemorrhage, Tranexamic Acid
- Trial name
- NCT03897621
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Wound Healing Time, Total Hip Arthroplasty (THA)
Wound Healing, Dressing Type, and Dressing Change Frequency in THA
Surgical wound complications following primary total hip arthroplasty remain a significant clinical challenge despite advances in wound care technologies.
- Trial name
- CAP-HIP (NCT07655388)
- Testing
- VACUTEX™ wound dressing, Octenisept® wound care dressing
- Where
- Serbia
- Volunteers
- 90 people
- Sponsor
- Clinical Center of Vojvodina
Arthropathy of Knee, Arthropathy of Hip
Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery
The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery.
- Conditions
- Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
- Trial name
- NCT05381818
- Testing
- Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Anemia
A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo to Reduce the Need for Blood Transfusions and Reduce the Occurrence of Severe Anemia During the Time Period Surrounding Total Hip Replacement Surgery
The purpose of this study is to evaluate the safety and effectiveness of two different dosing schedules of epoetin alfa versus placebo for decreasing the need for blood transfusions and preventing the occurrence of severe anemia…
- Trial name
- NCT00269958
- Testing
- epoetin alfa
- Volunteers
- 208 people
- Sponsor
- Janssen-Ortho Inc., Canada
Antibiotic Prophylaxis Surgery
Efficacy and Safety of Intraosseous Antibiotic Prophylaxis in Total Hip Replacement
The goal of this clinical trial is to learn if intraosseous antibiotic (cefazolin) administration can improve antibiotic levels in adults undergoing primary total hip replacement.
- Trial name
- NCT07549542
- Testing
- CeFAZolin 1000 MG, Saline (0.9%, sterile, for infusion)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
Immune Responses, Post Operative Recovery
Comparative Study Between the Effects of Deep Versus Moderate Neuromuscular Blockade on Postoperative Recovery and Immune Function in Patients Undergoing Total Hip Replacement Surgery.
. The investigators hypothesized that DNMB ( Deep NeuroMuscular Block) would yield superior postoperative recovery quality and attenuate the surgery-induced immune suppression compared to MNMB ( Moderate NeuroMuscular Block)in…
- Trial name
- NCT07870954
- Testing
- ToF ( Train of Four) Scan
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Total Hip Arthroplasty, Computer-Assisted Surgery
Pre-Op THA Modelling
Replacing diseased hip joints with prosthetic implants in a procedure called total hip arthroplasty (THA) is associated with high rates of patient satisfaction, pain relief, and functional improvement when the implant is…
- Trial name
- NCT05221554
- Testing
- Imageless computer-navigated THA surgery, Standard of care THA surgery, CT-based Computer-navigated THA surgery
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hip Replacement
Surgical Adhesive Drapes for Prevention and Healing of Wound Infections After Total Hip Arthroplasty
The purpose of this study is to support the rational use of iodophor-impregnated surgical adhesive drapes for preventing wound infections after total hip arthroplasty.
- Trial name
- NCT02707302
- Testing
- Iodophor-impregnated adhesive drapes group, Iodophor-free adhesive drapes group
- Volunteers
- 120 people
- Sponsor
- Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Venous Thromboembolism
Rivaroxaban (10mg) Given Once Daily in Patients Undergoing Total Hip Replacement Compared to Enoxaparin
The purpose of this study is to assess if 10 mg BAY 59-7939, taken once daily as a tablet, is safe and prevent blood clot which may form after total hip replacement operation.
- Trial name
- NCT00329628
- Testing
- Rivaroxaban (BAY59-7939), Enoxaparin
- Where
- 215 sites in United States, Argentina and 26 more
- Volunteers
- 4,541 people
- Sponsor
- Bayer
Osteoarthritis, Hip Dislocation
Supine Sleeping After Total Hip Replacement
Aim of the current study is to test the non-inferiority hypothesis of differences in early hip dislocation between a group of patients who will be restricted to sleep in supine position and a group without restricted sleeping…
- Trial name
- NCT02107248
- Testing
- Sleep position: no restrictions, Sleep position: supine
- Where
- Netherlands
- Volunteers
- 456 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Arthritis of Hip, Fracture of Femur
Medial Wedge Insoles to Improve Gait in Persons After Total Hip Replacement
The study will test the hypothesis, that the use of medial wedge insoles in people participating in comprehensive rehabilitation between 1-6 months after total hip replacement, and not having a varus deformity of the knee or…
- Conditions
- Arthritis of Hip, Fracture of Femur, Aseptic Necrosis, Dysplasia; Hip
- Trial name
- NCT05736016
- Volunteers
- 100 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Pain, Postoperative
Analgesic Efficacy, Safety and Tolerability of Two Paracetamol-Containing Solutions in Post-Surgical Hip Replacement Pain
The aim of the study is to evaluate the therapeutic efficacy, safety and local tolerability of two different paracetamol-containing solutions in postoperative total hip replacement.
- Trial name
- NCT00508495
- Testing
- Paracetamol (acetaminophen), Paracetamol 1% solution, 0.9% sodium chloride solution
- Where
- 8 sites in Hungary
- Volunteers
- 148 people
- Sponsor
- Baxter Healthcare Corporation
Hip Fractures, Hip Injuries
The Effect of Perioperative Heated Sock Use in Preventing Hypothermia During Total Hip Prosthesis Surgery
Warm sock application; It has been proven that wearing battery-operated warm socks on patients in the preoperative period strengthens the central thermoregulation system, maintains core body temperature, controls the shivering…
- Trial name
- NCT06541054
- Testing
- WARM SOCKS
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul University - Cerrahpasa
Developmental Dysplasia of the Hip
AI-assisted Preoperative Planning Technology for THA for DDH
In this study, the investigators retrospectively collected DDH case data of THA assisted by AI 3D planning and THA assisted by traditional planning.
- Trial name
- NCT05929105
- Testing
- artificial intelligence (AI)-assisted three-dimensional preoperative planning technology, X-ray film template for 2D planning
- Where
- China
- Volunteers
- 61 people
- Sponsor
- General Hospital of Ningxia Medical University
Hip Arthroplasty
Hospital for Special Surgery Hip Arthroplasty Cohort
Total joint replacements are some of the most successful medical devices developed over the last fifty years. They enable millions of people to remain ambulatory and pain free, with minimal risk.
- Trial name
- NCT00454506
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthritis
Mindfulness Meditation for Surgical Pain and Anxiety
Health care professionals are dedicated to the ongoing evaluation of the peri-operative experience, and always striving to improve patient satisfaction.
- Trial name
- NCT04932499
- Testing
- Standard of Care, Mindfulness Meditation
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Calgary