Clinical trials: Total Intravenous Anesthesia
Vision; Disorder, Loss
The Influence of Prone Position for Spinal Surgery on Visual Acuity
This study investigated the effect of desflurane and propofol anesthesia on visual acuity in patients in prone position for spinal surgery.
- Trial name
- NCT03644641
- Testing
- Desflurane Group, Propofol Group
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Hradec Kralove
Anesthesia, Intravenous, Electroencephalography
Remifentanil Effect on Burst Suppression Ratio
The goal of this clinical trial is to determine whether remifentanil has a facilitating effect on the generation of burst suppression by propofol in adult patients (18-60 years) candidates for elective surgery who require…
- Conditions
- Anesthesia, Intravenous, Electroencephalography, Burst Suppression
- Trial name
- NCT06237101
- Testing
- High dose of remifentanil, Medium dose of remifentanil
- Where
- 2 sites in Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Colorectal Cancer Metastatic, Survival Rate
The Effects of General Anesthetics on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and Mechanism Involved
The body immunity is important to the development of tumor. The immune system is in charge of monitoring and cleaning tumor cells in circulation. Anesthesia may alter the immune response and affect the elimination of tumor cells.
- Conditions
- Colorectal Cancer Metastatic, Survival Rate, General Anesthetics Toxicity, Lymphocyte Destruction
- Trial name
- NCT03193710
- Testing
- Propofol, Sevoflurane, Remifentanil
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Guizhi Du
Anesthesia
Total Intravenous Anesthesia in Patients Undergoing Craniotomy
Craniotomy presents true anesthetic challenges, mainly due to the need to optimize cerebral perfusion, facilitate brain relaxation, achieve rapid emergence for neurologic assessment, and minimize perioperative complications.
- Trial name
- NCT07105618
- Testing
- Dexmedetomidine, Fentanyl, Magnesium
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Zagazig University
Anesthesia
The TI.VA Algorithm: A First-in-Humans Test.
The TI.VA algorithm is a new method to titrate the anesthetic drug concentrations whenever the planned level of anesthesia results to be not appropriate to blunt the patient's reaction to surgical stimulation.
- Trial name
- TIVAly (NCT05199883)
- Testing
- TI.VA algorithm: decision support system
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Neuromuscular Block
Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty
The present study is designed to evaluate and compare the efficacy of intrathecal dexmedetomidine (DEX) as an adjuvant to Levobupivacaine in spinal anaesthesia and DEX's intravenous administration, without loading dose…
- Trial name
- NCT02966249
- Testing
- Levobupivacaine, Dexmetomidine intravenously, Normal Saline added intrathecally
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- KAT General Hospital
Emergence Delirium
Emergence Delirium in Children: Total Intravenous Anesthesia With Propofol and Remifentanil Versus Inhalational Sevoflurane Anesthesia
Emergence delirium (ED) refers to a wide variety of behavioural disturbances that are commonly seen in children following emergence from anesthesia.
- Trial name
- NCT00885443
- Testing
- Propofol, sevoflurane
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Unruptured Cerebral Aneurysm
Identification of Genetic Polymorphisms Related to Propofol Requirement and Recovery Through Genome-wide Association Study (GWAS) in Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population
In neurosurgical anesthesia, propofol based total intravenous anesthesia (TIVA) is frequently used due to brain relaxation and less effect on electrophysiologic monitoring.
- Trial name
- NCT03087383
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Yonsei University
Anesthesia, Total Intravenous Anesthesia
The Effect of Anesthetic Methods on Gastrointestinal Motility
The goal of this randomized controlled single blinded study is to compare the effect of the type of anesthesia on gastrointestinal motility in patients scheduled for laparoscopic sleeve gastrectomy.
- Trial name
- NCT05951686
- Testing
- Desflurane, Remifentanil infusion, Fresh gas
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Bozyaka Training and Research Hospital
Gastrostomy
The Effect of Total Intravenous Anesthesia and Volatile Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Laparoscopic or Robotic Assisted Gastrectomy
The aim of this study was to investigate the effects of total intravenous and inhalation anesthesia on the damage of endothelial glucocorticoids by comparing the concentration of syndecan-1 before and after laparoscopic or…
- Trial name
- NCT04183296
- Testing
- propofol, sevoflurane
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Yonsei University
Thyroid Surgery Intraoperative Nerve Monitoring (IONM) Recurrent Laryngeal Nerve Function Dexmedetomidine vs Midazolam (Anesthetic Agents)
EFFECT OF DEXMEDETOMİDİNE ON RECURRENT LARYNGEAL NERVE MONİTORİNG: A COMPARATİVE STUDY WİTH MİDAZOLAM
This prospective observational study evaluated the effect of dexmedetomidine compared with midazolam on intraoperative monitoring of the recurrent laryngeal nerve during thyroid surgery.
- Trial name
- DEX-RLN (NCT07195214)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Amasya University
Pain, Postoperative, Nausea and Vomiting, Postoperative
QUALITY OF RECOVERY AFTER INTRAOPERATIVE MORPHINE OR METHADONE
Introduction. Despite the advantages associated with the use of remifentanil during total intravenous anesthesia (TIVA), it has been observed a frequent difficulty in the control of postoperative pain due to the risk of…
- Trial name
- NCT03045133
- Testing
- Methadone, Morphine
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Hyperglycemia Stress
TIVA and VIMA on Blood Glucose and Insulin Levels in Lung Lobectomy Patients
The purpose of this study was to evaluate the efficacy and safety of sevoflurane-only Volatile induction and maintenance anesthesia (VIMA) and total intravenous anesthesia (TIVA) using only propofol in adult patients scheduled…
- Trial name
- NCT03094533
- Testing
- TIVA, VIMA
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yeungnam University College of Medicine
Arthroplasty Complications, Knee Osteoarthritis
Virtual Reality Hypnosis in Total Knee Arthroplasty Under Spinal Anesthesia
For many years, total knee arthroplasty (TKA) has been a common and effective procedure to treat chronic refractory joint pain. Although efforts must be pursued, as general anesthesia remains the main tendency for TKA.
- Conditions
- Arthroplasty Complications, Knee Osteoarthritis, Anesthesia Complication, Hypnotic; Anxiety Disorder
- Trial name
- NCT05707234
- Testing
- VRH, Midazolam sedation
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University of Liege
Esophageal Cancer
Total Intravenous Anesthesia and Recurrence Free Survival
The investigators propose to compare recurrence-free survival in patients having potentially curative (Stages 1-3) surgery for esophageal cancer who will be randomly assigned to propofol-based total intravenous anesthesia or…
- Trial name
- NCT04513808
- Testing
- Propofol-based total intravenous anesthesia, Sevoflurane intravenous anesthesia
- Where
- China
- Volunteers
- 1,614 people
- Sponsor
- The Cleveland Clinic
Remifentanil, Analgesia
Optimal Dosage of Remifentanil for Vertebroplasty
Percutaneous vertebroplasty has become a mainstay in the management of osteoporotic and malignant vertebral fractures. Procedural analgesia and sedation (PAS) with propofol and remifentanil may provides optimal hypnotic and…
- Trial name
- NCT05876039
- Testing
- Initial remifentanil effect-site concentration
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Elective Surgical Procedures, Anesthesia, Intravenous
Comparison Between Propofol Concentration in Exhaled Breath and Blood Plasma Using the Exhaled Drug Monitor "Edmon"
Edmon is the first Communauté Européenne (CE) marked medical device able to continuously measure propofol in the exhaled breath of patients under sedation or anaesthesia with propofol.
- Trial name
- ProDect (NCT04586998)
- Testing
- Exhaled drug monitor "Edmon"
- Sponsor
- B. Braun Melsungen AG
Hypotension
Remimazolam Versus Propopol Based Total Intravenous Anesthesia for Breast Surgery
Comparison of the incidence of hypotension under remimazolam and propofol-based anesthesia in patients undergoing breast surgery under general anesthesia
- Trial name
- NCT05375747
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Blood Pressure, Hypotension
Hypotensive Effect of Anaesthesia With TCI
Hypotension will often complicate induction of anaesthesia. The investigators want to test the hypothesis that Target Controlled Infusion, as opposed to Velocity Controlled Infusion, leads to less degree of hypotension.
- Trial name
- HEAT (NCT02733406)
- Testing
- Target Controlled Infusion, Velocity Controlled Infusion
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Umeå University
Benign/Malignant Neoplasm, Long Bone Fracture
Correlation of Bispectral Index Score and Total Intravenous Anesthesia (TIVA)
General Anesthesia is usually produced by an intravenous agent and then maintained with a breathing agent till the surgery is completed.
- Trial name
- NCT01618539
- Testing
- propofol
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Rutgers, The State University of New Jersey