Clinical trials: Total Joint Arthroplasty
Hematoma
Intra-articular Volumetric Assessment After Total Knee Arthroplasty
The purpose of the study: is to quantify the amount of post-operative effusion or hematoma present after total knee arthroplasty pre-operatively, post-operative day #0,1.
- Trial name
- TKA (NCT02821325)
- Testing
- MRI
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Loma Linda University
Primary Osteoarthritis, Post-Traumatic Osteoarthritis of Hip
Avenir® Cemented Hip Stem - PMCF
The objective of this post-market clinical follow-up study is to confirm the safety and performance of the Avenir® Cemented Hip stem when used in primary total hip arthroplasty.
- Conditions
- Primary Osteoarthritis, Post-Traumatic Osteoarthritis of Hip, Femoral Neck Fractures, Femoral Head Necrosis
- Trial name
- NCT03396224
- Where
- 3 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Venous Thromboembolism, Total Hip Arthroplasty (THA)
The Effect of a VTE Prevention Care Bundle in Total Hip Arthroplasty Patients
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), remains a critical and potentially life-threatening complication following total hip arthroplasty (THA).
- Conditions
- Venous Thromboembolism, Total Hip Arthroplasty (THA), Deep Vein Thrombosis
- Trial name
- VTE-CARE-THA (NCT07702903)
- Testing
- VTE Prevention Care Bundle, Standard Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Murat Erten
Arthritis, Knee Arthropathy
Robotic-Assisted Versus Conventional Total Knee Arthroplasty(TKA)
Robotic-assisted total knee arthroplasty (TKA) was introduced to attempt to enhance the precision of bone preparation, component alignment and ultimately improve clinical results and survivorship of TKA.
- Conditions
- Arthritis, Knee Arthropathy, Robotics
- Trial name
- NCT03659318
- Testing
- Robotic-assisted TKA, Conventional TKA
- Volunteers
- 674 people
- Sponsor
- Ewha Womans University
Bilateral Total Knee Arthroplasty
Efficacy of Pain Control in Different Bupivacaine Dose in Periarticular Injection in Bilateral Total Knee Arthroplasty
To study efficacy of postoperative pain control of different concentrations of bupivacaine for periarticular infiltration, part of multimodal analgesia, in bilateral total knee arthroplasty.
- Trial name
- NCT03249662
- Testing
- bupivacaine 200 mg, bupivacaine 100 mg
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Knee Osteoarthritis, Bone; Deformity, Congenital
COREV 2.0 PMCF-Study on Manual and Navigated Revision Knee Patients
The Columbus® Revision endoprosthetic system is bearing the CE-mark. This means that within the scope of this observational study the patient will not be subjected to any additional stressful, study-related medical examinations…
- Conditions
- Knee Osteoarthritis, Bone; Deformity, Congenital, Prosthesis Failure, Prosthesis-Related Infections
- Trial name
- COREV (NCT05113303)
- Testing
- Navigated Revision Total Knee Arthroplasty, Manual Revision Total Knee Arthroplasty
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Knee Osteoarthritis
Journey II vs Persona Knee Systems - RCT
This study compares and evaluates differences in patient-reported outcome, survivorship and radiological analysis between patients undergoing total knee arthroplasty with use of either Zimmer Biomet PERSONA Posterior Stabilized…
- Trial name
- NCT05038670
- Testing
- Total Knee Replacement
- Where
- Poland
- Volunteers
- 45 people
- Sponsor
- Medical University of Warsaw
Wound Healing
Efficacy and Patient Satisfaction With AQUACEL® Ag Surgical Dressing Compared to Standard Surgical Dressing
The objective of this study is to determine the safety and effectiveness of the AQUACEL® Ag Surgical Dressing (treatment group) as compared to prepackaged island wound dressings consisting of traditional tape and gauze (control…
- Trial name
- NCT01258270
- Testing
- Postop Dressing
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Osteoarthritis, Knee
Moving Well for Total Knee Arthroplasty (TKA)
The purpose of this study is to assess the efficacy of a behavioral intervention, Moving Well, in improving levels of anxiety and depression for patients undergoing total knee arthroplasty (TKA).
- Trial name
- NCT05217420
- Testing
- Moving Well, Staying Well
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Weill Medical College of Cornell University
Pain Postoperative, Osteoarthritis
Comparing Efficiency of Mirogabalin and Pregabalin in Primary TKA
The goal of this RCT is to compare efficacy between mirogabalin and pregabalin in pain reducing after unilateral primary total knee arthroplasty.
- Conditions
- Pain Postoperative, Osteoarthritis, Total Knee Arthroplasty
- Trial name
- NCT06328062
- Testing
- Mirogabalin, Pregabalin
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Thammasat University Hospital
Total Knee Anthroplasty
Genicular Nerve Block Added to Femoral Nerve Block for Analgesia After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a common orthopedic procedure in which effective postoperative pain management is important for early mobilization and rehabilitation.
- Trial name
- GNB-FNB (NCT07478783)
- Testing
- Ultrasound-guided Femoral Nerve Block, ltrasound-guided Genicular Nerve Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Venous Cannulation Pain, Total Knee Arthroplasty
Feasibility Study of Peripheral Venous Cannulation Pain in Predicting Acute Pain After Total Knee Arthroplasty
The goal of this prospective observational study is to explore the feasibility of preoperative peripheral venous cannulation pain score in predicting acute pain after total knee arthroplasty, including resting pain and…
- Conditions
- Venous Cannulation Pain, Total Knee Arthroplasty, Movement-evoked Pain, Acute Pain
- Trial name
- NCT06002724
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Postoperative Pain
Efficacy of Epidural Steroid for Controlling Pain After Primary TKA
The purpose of this study is to determine efficacy of epidural steroid for postoperative pain control after TKA
- Trial name
- NCT02001259
- Testing
- epidural triamsinolone, epidural lidocaine
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Thammasat University
Knee Disease, Nerve Pain
Triple Injection Peri-sartorius (TIPS) Block
Comparison between the pain scores after total knee arthroplasty in patients receiving triple injection peri-sartorius (TIPS) block versus femoral nerve block (FNB)
- Trial name
- NCT05289427
- Testing
- ultrasound guided triple injection peri-sartorius block, Femoral Nerve Block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Staphylococcus Aureus
Probiotics Pilot Project
This pilot study is designed to determine if ingestion of Bacillus probiotics can cause alteration in levels of S. aureus colonization in the nose and intestine in preoperative orthopedic patients undergoing elective primary TJA.
- Trial name
- NCT04247854
- Testing
- Bacillus subtilis probiotic
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rothman Institute Orthopaedics
Osteoarthritis, Knee
Residual Pain After Successful Implant of Metaphyseal Sleeves in Total Knee Arthroplasty
: Total knee revision arthroplasty is increasing in daily practice and will become more relevant in the years to come. Bone loss is a significant challenge in total knee arthroplasty (TKA) especially in revision procedures.
- Trial name
- NCT04995679
- Testing
- Implant of metaphyseal sleeves in Total knee arthroplasty
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- University of Milan
Osteoarthritis, Knee, Arthropathy of Knee Joint
Comparison of Cruciate Retaining and Posterior Stabilized Total Knee Arthroplasty
Several authors and large registries have suggested the potential for an increased risk of all-cause revision with the use of posterior cruciate-substitution (PS) total knee arthroplasty (TKA).
- Trial name
- NCT06124651
- Testing
- Total knee replacement with cruciate retaining femoral component, Total knee replacement with cruciate substituting femoral component
- Volunteers
- 300 people
- Sponsor
- Ewha Womans University
Shoulder Arthroplasty
Prospective Low Dose CT for Total Shoulder Arthroplasty/Reverse Shoulder Arthroplasty
This study is a prospective, departmental funded study examining the outcomes of simulated Low Dose CT scans compared to Conventional Dose CT scans in patients who present to Duke University for total shoulder arthroplasty or…
- Trial name
- NCT05350319
- Testing
- A low-dose CT scan of the shoulder
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Duke University
Knee Arthroplasty, Total
Optetrak Knee System Post Market Clinical Follow-Up
A Post-Market Domestic (US) and International Data Collection to Assess the Optetrak Knee System
- Trial name
- NCT05788757
- Testing
- Optetrak Total Knee System
- Where
- 3 sites in United States
- Volunteers
- 4,588 people
- Sponsor
- Exactech
Pain Management, TKA
Photobiomodulation Therapy for Pain Control in Post-Operative Total Knee Arthroplasty Patients: A Pilot Study
A pilot study to assess the efficacy and feasibility of PBMT for pain control in patients undergoing a TKA and are discharged the same day from an ambulatory surgery center.
- Conditions
- Pain Management, TKA, Post Operative Analgesia, Low Level Laser Therapy
- Trial name
- NCT07750912
- Testing
- LightForce XLI
- Volunteers
- 15 people
- Sponsor
- Mohammad Burney, MD
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