Clinical trials: Total Knee Anthroplasty
Total Knee Anthroplasty, Total Knee Arthroplasty Recovery
The Effects of Mir Shakeel Teleintegrated Therapy Plan in Patients Undergoing Total Knee Arthroplasty
This randomized controlled trial aims to evaluate the effectiveness of a newly developed Modified Structured Telerehabilitation Intervention Protocol (MSTITP) compared with conventional in-person physical therapy in patients…
- Trial name
- RCT (NCT07239258)
- Testing
- Mir Shakeel Teleintegrated Therapy plan, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Lincoln University College Malaysia
Total Knee Anthroplasty, Regional Anesthesia
The Sacral Erector Spinae Plane Block in Total Knee Arthroplasty
The goal of this observational study is to learn about the analgesic efficacy and postoperative recovery of two locoregional anesthesia combinations in patients > 18 years (ASA I-III), scheduled for unilateral TKA under spinal…
- Trial name
- sacral ESP (NCT07017400)
- Testing
- Local Anesthetic Injection
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- San Giovanni di Dio Hospital
Acupuncture Analgesia, Acupuncture
ACU_Knee: Role of Acupuncture in Knee Prosthetic Surgery
Post-operative analgesia after total knee arthroplasty (TKA) has always been a challenge in the anesthesiological setting, having to combine good pain control and the need for early mobilization, both factors that can affect the…
- Conditions
- Acupuncture Analgesia, Acupuncture, Acupuncture Therapy, Total Knee Anthroplasty
- Trial name
- ACU_Knee (NCT07123805)
- Testing
- Acupuncture group
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Total Knee Anthroplasty, Nerve Block
Liposomal Bupivacaine Versus Ropivacaine With Perineural Dexamethasone or Dexmedetomidine as Adjuncts for Adductor Canal Block Combined With IPACK Block in Total Knee Arthroplasty
Effective postoperative pain management remains a cornerstone of enhanced recovery protocols following total knee arthroplasty (TKA).
- Conditions
- Total Knee Anthroplasty, Nerve Block, Ropivacaine, Liposomal Bupivacaine
- Trial name
- NCT07509866
- Testing
- Liposomal bupivacaine (LB), Ropivacaine with Perineural Dexamethasone, Ropivacaine with Perineural Dexmedetomidine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology
Total Knee Anthroplasty
Investigation of the Individual Fatigue Response During Blood Flow Restriction Training
The aim of the present pilot study is to investigate the feasibility of an exercise pressure response approach for assessing physiological strain during BFR training in a clinically supervised setting.
- Trial name
- NCT07611526
- Testing
- Cycling BFR
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University Hospital, Bonn
Knee Arthroplasty, Total, Knee Arthritis, Osteoarthritis
The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery
The aim of this clinical trial is to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative blood loss, thromboembolic complications, and hospitalization duration in patients undergoing…
- Conditions
- Knee Arthroplasty, Total, Knee Arthritis, Osteoarthritis, Total Knee Anthroplasty, Blood Loss
- Trial name
- NCT07089251
- Testing
- low-dose epinephrine and tranexamic acid, Tranexamic Acid (TXA) treatment
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- King Abdullah International Medical Research Center
Total Knee Anthroplasty, Robotic Surgery
Early Clinical and Radiological Outcomes of a Novel Robotic TKA System
This study aimed to evaluate the early clinical and radiological outcomes of robot assisted total knee arthroplasty, and to determine the efficiency and safety of its bone resection and implant positioning of the novel robot…
- Trial name
- RA-TKA (NCT06638047)
- Testing
- robotic-assisted TKA, CI-TKA
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University Third Hospital
Osteo Arthritis of the Knee, Total Knee Anthroplasty
Dinalbuphine Sebacate in Postoperative Pain Control After TKA
To evaluate the effectiveness of Dinalbuphine Sebacate for controlling subacute pain after total knee arthroplasty
- Trial name
- Naldebain (NCT07140510)
- Testing
- Dinalbuphine Sebacate, Normal Saline
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Total Knee Anthroplasty, Cryotherapy
Monocentric Randomised Controlled Trial Assessing Cryocompression Following Total Knee Replacement
Immediately following surgery, icepacks are commonly used to decrease inflammation and reduce pain and have demonstrated to decrease post-operative opioid consumption.
- Conditions
- Total Knee Anthroplasty, Cryotherapy, Compression
- Trial name
- CryoTKR (NCT07366736)
- Testing
- Cryotherapy, Game Ready
- Where
- France
- Volunteers
- 138 people
- Sponsor
- Clinique des Cèdres
Total Knee Anthroplasty, Osteoarthritis(Primary)
COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty
Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA.
- Conditions
- Total Knee Anthroplasty, Osteoarthritis(Primary), Osteoarthritis (OA) of the Knee, Bilateral Knee Osteoarthritis
- Trial name
- COSTI (NCT06809998)
- Testing
- Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL)., Band-Aid
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Total Knee Anthroplasty
"The Effect of AI-Assisted Mobilization Education on Kinesiophobia and Readiness for Hospital Discharge in Patients Undergoing Total Knee Arthroplasty''
The aim of this study is to investigate the effect of artificial intelligence-assisted mobilization education provided to patients undergoing total knee arthroplasty on their level of kinesiophobia and readiness for hospital…
- Trial name
- NCT07694895
- Testing
- Artificial intelligence-assisted mobilization education video
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Kocaeli University
Total Knee Anthroplasty, Epidural Analgesia
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty
The goal of this clinical trial is to compare two different epidural analgesia delivery methods for pain control after total knee arthroplasty in adults undergoing elective surgery.
- Trial name
- NCT07605208
- Testing
- Programmed intermittent epidural bolus 6 ml, continuous epidural infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Total Knee Anthroplasty
The Effect of Kinesio Taping on Mobility, Pain, Balance and Daily Activities in Total Knee Replacement Patients
Total knee arthroplasty (TKA) is a surgical procedure performed to relieve pain and functional limitations caused by advanced gonarthrosis that cannot be managed with conservative methods.
- Trial name
- NCT06911814
- Testing
- kinesio taping, THE EXERCİSE
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Total Knee Anthroplasty, Patient Reported Outcome Measurements
Recovery Trajectories After Total Knee Arthroplasty
This prospective cohort study aimed to compare recovery trajectories following cruciate-retaining (CR) and posterior-stabilized (PS) total knee arthroplasty (TKA) using rehabilitation-centered patient-reported outcome measures…
- Conditions
- Total Knee Anthroplasty, Patient Reported Outcome Measurements, Cruciate Ligament Reconstruction
- Trial name
- NCT07595861
- Testing
- Cruciate-Retaining Total Knee Arthroplasty, Posterior-Stabilized Total Knee Arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University