Clinical trials: Total Knee Replacement Revision
Tantalum, Bone Loss
Allograft and Tantalum Cone Reconstruction in TKA Revision
A new surgical technique of reconstruction for bone loss in TKA revision using tantalum cone and allograft. Study of radiological and clinical outcomes.
- Conditions
- Tantalum, Bone Loss, Allograft
- Trial name
- NCT05510011
- Where
- France
- Volunteers
- 76 people
- Sponsor
- University Hospital, Montpellier
Osteoarthritis, Revision Arthroplasty
Pro Osteon Bone Void Filler Study
This study was designed to observe the outcomes of Pro Osteon according to its cleared indications for use.
- Trial name
- PO (NCT00858598)
- Sponsor
- Zimmer Biomet
Osteoarthritis
A Post-Market Retrospective Study on Revision Total Knee Arthroplasty Using Medacta GMK® Revision Prosthesis
This is a retrospective, single-site observational study, designed to assess the clinical outcomes and collect safety data of GMK Revision knee system used for primary or revision total knee arthroplasty at minimum two years…
- Trial name
- NCT02912351
- Testing
- Patient record review, Radiographs, and questionaires.
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Revision Total Knee Arthroplasty Because of, Loosening
Joint Line Reconstruction in Navigated Total Knee Arthroplasty Revision
Hypothesis: navigated revision total knee arthroplasty results in a more precise reconstruction of preoperatively planned joint line than conventional revision total knee arthroplasty (rTKA).
- Conditions
- Revision Total Knee Arthroplasty Because of, Loosening, Instability, Impingement
- Trial name
- NavRevKnie (NCT01601756)
- Testing
- navigated revision knee arthroplasty, conventional revision knee arthroplasty
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Arthroplasties, Knee Replacement, Revision Arthroplasty
Patient Outcomes With Robotic-Assisted Total Knee Arthroplasty
This is a post-market multicentre study that has been implemented to confirm safety and performance of cemented CR/UC and PS Apex Knee implants in primary or revision Robotic Assisted Total Knee Arthroplasty up to 10-year follow…
- Trial name
- NCT06203756
- Testing
- Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex UC, Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex PS, Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex Revision
- Where
- 6 sites in United States
- Volunteers
- 713 people
- Sponsor
- Corin
Knee Arthroplasty, Total, Gait Analysis
Gait Kinematics After Primary Total Knee Arthroplasty (TKA) Versus Revision TKA
The functional outcomes after TKA are satisfying with a full recovery at 6 months - 1 year. Nevertheless, the revisions of TKA have often lower functional results than primary TKA with a long delay of recovery.
- Trial name
- Stryker-KneeKG (NCT03898544)
- Testing
- Group primary TKA, Group TKA revision
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Hospices Civils de Lyon
Rheumatoid Arthritis, Non-inflammatory Degenerative Joint Disease
PMCF Study on the Safety, Performance and Clinical Benefits Data of the NexGen TM Augmentation Patella
The study is a single-center, retrospective and prospective, non-randomized, non-controlled and consecutive series post-market study.
- Conditions
- Rheumatoid Arthritis, Non-inflammatory Degenerative Joint Disease, Functional Deformity, Revision Total Knee Arthroplasty
- Trial name
- NCT05253976
- Where
- Switzerland
- Sponsor
- Zimmer Biomet
Total Knee Arthroplasty
Joint Movement to Increase Range of Motion in Knee Joint After Primary Total Knee Arthroplasty
The goal of this clinical trail is to investigate if specific active exercises, with a certain daily frequency improves the range of motion (ROM) in the knee joint after primary- or revision total knee arthroplasty (TKA) The main…
- Trial name
- ROM (NCT06188091)
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 83 people
- Sponsor
- Nordsjaellands Hospital
Knee Osteoarthritis
Using Intraoperative Sensing Technology to Evaluate Revision Total Knee Arthroplasty
This study will attempt to draw relationships between the soft-tissue related complications contributing to early TKA revision and the loading and positional patterns from intraoperative tibial trial sensors.
- Trial name
- NCT03023410
- Testing
- VERASENSE
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Orthosensor, Inc.
Surgical Wound, Revision Total Knee Arthroplasty
Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty
This study evaluates surgical site complications in subjects undergoing revision of a total knee arthroplasty when closed incision negative pressure therapy is used to manage the closed incision, as compared to a standard of care…
- Conditions
- Surgical Wound, Revision Total Knee Arthroplasty, Wounds and Injuries, Joint Disease
- Trial name
- PROMISES (NCT03274466)
- Testing
- Closed Incision Negative Pressure Therapy (ciNPT), Standard of Care Dressing
- Where
- 17 sites in United States
- Volunteers
- 294 people
- Sponsor
- KCI USA, Inc
Revision Total Hip Arthroplasty, Revision Total Knee Arthroplasty
Tissue Culture Versus Swab Culture in Prosthetic Joint Infections
The main purpose of this study is to compare the effectiveness and accuracy of tissue cultures and swab cultures to diagnose prosthetic joint infection.
- Trial name
- NCT01482533
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
Prosthesis-related Infections, Wound Complications
Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.
The purpose of this study is to determine the efficacy of a negative pressure wound therapy (NPWT) system after revision total knee and hip arthroplasty in patients at high risk for infection.
- Conditions
- Prosthesis-related Infections, Wound Complications, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT02127281
- Testing
- Prevena
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- The Cleveland Clinic
Joint (Knee or Hip Replacement), Infection as Complication of Medical Care
Swiss Revision Cohort
This study follows patients with infections after a joint replacement over time. During follow-up, treatment outcomes are carefully measured to determine whether the infection can be cured.
- Trial name
- REVCO (NCT07473089)
- Testing
- Revision for periprosthetic joint infections of the hip, knee, shoulder, elbow or ankle
- Where
- 5 sites in Switzerland
- Volunteers
- 329 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Total Knee Arthroplasty, Revision Total Knee Arthroplasty
Multigen Plus CCK and AMF TT Cones Follow Up Study
This study is aimed to provide a clinical and radiographic evaluation of 68 condylar-constrained Total Knee Arthroplasty (TKA) using a single type of prosthesis (Multigen Plus CCK configuration), alone or involving the AMF TT…
- Trial name
- NCT05314491
- Testing
- Multigen Plus CCK, AMF TT cones
- Where
- 3 sites in Portugal, Slovakia and 1 more
- Volunteers
- 68 people
- Sponsor
- Limacorporate S.p.a
Total Knee Arthroplasty, Reinfection
Reinfection and Re-revision Rates of Periprosthetic Knee Infection Under Four Different Surgical Strategies
A single-center retrospective cohort study was conducted in the Department of Orthopedics, the First Affiliated Hospital of Fujian Medical University.
- Conditions
- Total Knee Arthroplasty, Reinfection, Aseptic Loosening, Revision
- Trial name
- NCT07232771
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Knee Osteoarthritis, Knee Arthroplasty
Evaluation of Fixation Achievable in Revision Total Knee Arthroplasty Implementing Latest-Generation Implant Technology
This is a prospective randomized control trial that aims to investigate fixation of implants after revision total knee replacement.
- Trial name
- NCT03276351
- Testing
- Long-Stemmed with Hybrid Fixation, Short-Stemmed with Augmented Fixation
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Total Knee Arthroplasty, Total Hip Arthroplasty Revision
Interventional Study Exploring the Occurrence of Surgical Site Infections.
Interventional study exploring surgical site complication occurrences in high-risk revision patients undergoing TKA or THA using NPWT.
- Conditions
- Total Knee Arthroplasty, Total Hip Arthroplasty Revision, Total Knee Arthroplasty Revision
- Trial name
- NCT06661473
- Testing
- Avance Solo Negative Pressure Wound Therapy
- Where
- 8 sites in United States
- Volunteers
- 104 people
- Sponsor
- Molnlycke Health Care AB
TKA Infection
Knee Hinge Prosthesis Following TKA Infection
Between 2009 and January 2016, the investigators included 49 patients from four hospitals in Lyon who had a Total Knee Arthroplasty (TKA) infection and who benefited of a knee arthroplasty revision with a rotating hinge…
- Trial name
- NCT02856971
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Hospices Civils de Lyon
Pain
Effects of Sustained-release Oral Sodium Nitrite on Postoperative Pain and Recovery Following Total Knee Arthroplasty
This study will determine whether a drug called sodium nitrite helps improve pain and post-operative recovery associated with knee replacement surgery.
- Trial name
- NCT05893160
- Testing
- JAN101 SR
- Sponsor
- University of Alabama at Birmingham
Arthrofibrosis of Knee
Stiffness and Low Dose Irradiation RCT
Acquired idiopathic stiffness (AIS) is a common complication following total knee arthroplasty (TKA). It is caused by excessive scar formation, which leads to pain, loss of motion, and functional impairment.
- Trial name
- LDI TKR RCT (NCT07767097)
- Testing
- Low-Dose External Beam Irradiation, Hinged Revision Total Knee Arthroplasty
- Where
- 4 sites in United States, Canada
- Volunteers
- 36 people
- Sponsor
- Mount Sinai Hospital, Canada