Clinical trials: Total Knee Replacement Surgeries
Total Knee Replacement, Arthroplasty
The Effect of Patellar Eversion on Functional Outcomes in Primary Total Knee Arthroplasty
Short and long term outcomes of total knee arthroplasty patients surgically exposed with patellar eversion are compared to those patients exposed by laterally retracting the patella.
- Conditions
- Total Knee Replacement, Arthroplasty, Patella
- Trial name
- NCT01777009
- Testing
- Primary Total Knee Replacement Surgery
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwell Health
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement
Brief Summary The goal of this clinical trial is to learn if nurse-led telehealth consultations can help detect complications and support recovery after total knee replacement surgery.
- Trial name
- NCT07058623
- Testing
- Nurse-Led Telehealth Consultation, Traditional In-Person Nursing Consultation
- Where
- Hong Kong
- Volunteers
- 98 people
- Sponsor
- Hospital Authority, Hong Kong
Orthopedic Surgery
Impact of a Technique of Massage During the First Week of Hospitalization on the Recycling of the Mobility of the Knee Further to the Installation of Knee Replacement
During fthe first postoperative days, physiotherapists supported patients with knee replacement in orthopaedics of Saint-Junien's and Limoges' hospitals.
- Trial name
- PTGMass (NCT02278627)
- Testing
- manual lymphatic drainage
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Limoges
Total Knee Arthroplasty, Total Hip Arthroplasty Revision
Interventional Study Exploring the Occurrence of Surgical Site Infections.
Interventional study exploring surgical site complication occurrences in high-risk revision patients undergoing TKA or THA using NPWT.
- Conditions
- Total Knee Arthroplasty, Total Hip Arthroplasty Revision, Total Knee Arthroplasty Revision
- Trial name
- NCT06661473
- Testing
- Avance Solo Negative Pressure Wound Therapy
- Where
- 8 sites in United States
- Volunteers
- 104 people
- Sponsor
- Molnlycke Health Care AB
Blood Loss
The Use of FLOSEAL to Reduce Bleeding in Total Knee Replacement Surgery
The purpose of this study is to determine if the agent, Floseal, can decrease the amount of blood patients lose after total knee replacement (TKR) surgery.
- Trial name
- NCT00990288
- Testing
- Hemostatic Matrix
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Hospital for Special Surgery, New York
Blood Loss
Blood Loss Between Surgical Blade and Unipolar Electrocautery in TKA
Using of surgical blade may have less blood loss than unipolar electrocautery in Total Knee Arthroplasty (TKA).
- Trial name
- TKA (NCT02108327)
- Testing
- surgical blade, electrocautery
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Thammasat University
Knee Osteoarthritis
Effect of Pre-surgery Neuromuscular Physiotherapy (PT)
Background: Osteoarthritis (OA) is a common degenerative condition of large weight-bearing joints, such as the hip and knee, as well as small hand joints.
- Trial name
- Omega (NCT00913575)
- Testing
- preoperative neuromuscular training, knee OA School
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- University of Zurich
Transcranial Direct Current Stimulation, Post Operative Pain
Effectiveness of Transcranial Direct Current Stimulation for TKR
Transcranial direct current stimulation (tDCS) is a technique of noninvasive cortical stimulation allowing significant modification of brain function used.
- Trial name
- NCT03898245
- Testing
- apply tDCS
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- SMG-SNU Boramae Medical Center
Knee Osteoarthritis
Telerehabilitation of Patients After Knee Surgery
This project is aimed to investigate the feasibility of employing communication and sensor technologies for the patient after a knee operation.
- Trial name
- NCT03731208
- Testing
- Telerehabilitation
- Where
- 2 sites in Denmark
- Volunteers
- 12 people
- Sponsor
- Aalborg University
Arthritis of the Knee
Unity Total Knee Replacement Using Two Different Surgical Techniques
This study will compare two different surgical methods used in total knee replacement with the Unity Total Knee Replacement System.
- Trial name
- NCT02145455
- Testing
- Unity Total Knee Replacement System
- Where
- United Kingdom
- Volunteers
- 111 people
- Sponsor
- Corin
Total Knee Arthroplasty
Accelerated Recovery for Total Knee Replacement Surgery With Preoperative Intravenous Iron Combined With Human Erythropoietin for Rapid Hematopoietic Mobilization to Prevent Postoperative Anemia
This study is a randomized, placebo-controlled, multicenter research design to investigate the effectiveness and safety of a single-dose intravenous iron combined with HuEPO hematopoietic mobilization before surgery in patients…
- Trial name
- Hematoboost (NCT05911438)
- Testing
- Ferric Derisomaltose Injection (Monoferric) and Human Erythropoietin Injection (EPIAO), Basic Treatment
- Where
- China
- Volunteers
- 419 people
- Sponsor
- West China Hospital
Arthroplasty Complications
Safety of Total Knee Replacement Surgery Before and After the Implementation of Enhanced Recovery Program
The objectives are to describe the transition from traditional care to an enhanced recovery program for the management of total knee arthroplasty, and to evaluate the effect on patient outcomes.
- Trial name
- NCT05028426
- Testing
- Enhanced recovery program
- Where
- France
- Volunteers
- 455 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Knee Osteoarthristis
Sleep TO Prevent Post-surgical Pain
This research study is being done to compare different methods of addressing sleep problems before total knee replacement surgery. These methods include Cognitive Behavioral Therapy and light exposure.
- Trial name
- STOPPP (NCT06976138)
- Testing
- Cognitive-Behavioral Therapy for Insomnia, Bright Light therapy via the Re-Timer®, Negative Ion exposure via IonMi Device
- Where
- 2 sites in United States
- Volunteers
- 252 people
- Sponsor
- Johns Hopkins University
Osteoarthritis (OA), Osteoarthritis (OA) of the Hip
Evaluation of Choose to Move Replacement Ready (CTM-RR)
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Total Knee Anthroplasty
- Trial name
- CTM-RR (NCT07696650)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- University of British Columbia
Arthroplasty, Replacement, Knee, Nerve Block
Does Continuous Adductor Canal Nerve Block Improve the Quality of Recovery for Outpatient Total Knee Arthroplasty Patients?
This is a randomized, double-blinded pilot study to determine whether patients undergoing ambulatory total knee arthroplasty (TKA) using a subvastus approach benefit from the addition of a continuous adductor canal nerve block…
- Conditions
- Arthroplasty, Replacement, Knee, Nerve Block, Anesthesia, Regional, Ambulatory Surgical Procedures
- Trial name
- NCT03038425
- Testing
- Normal Saline, Ropivacaine
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- Ottawa Hospital Research Institute
Total Knee Arthroplasty (TKA), Total Knee Arthroplasty \(TKA\)
Suzetrigine in TKA
Total knee replacements are among the most common and painful orthopedic procedures performed worldwide, often requiring intensive analgesia to support early ambulation and recovery.
- Conditions
- Total Knee Arthroplasty (TKA), Total Knee Arthroplasty \(TKA\), Total Knee Replacement, Total Knee Replacement Surgery
- Trial name
- NCT07864896
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Effects of Preoperative Education, and Follow-up Sessions of Patients With Total Hip and Knee Arthroplasty (ESIPPES)
The shortening of the length of stay implies rethinking the perioperative management (around the operative period), which precedes and immediately follows the operation, in order to ensure a good preparation of the patient and an…
- Trial name
- ESIPPES (NCT05452161)
- Testing
- Control group, Intervention group A, Intervention group B
- Where
- Switzerland
- Volunteers
- 163 people
- Sponsor
- Haute Ecole de Santé Vaud
Orthopedic Surgery, Rehabilitation
Comparison of Telerehabilitation and Usual Rehabilitation After Knee or Hip Surgery
After knee or hip replacement surgery, rehabilitation helps patients regain mobility, improve muscle strength, and return to their daily activities.
- Trial name
- TELEARTHROPOST (NCT07902505)
- Testing
- Standard Inpatient Rehabilitation, Telerehabilitation
- Where
- France
- Volunteers
- 216 people
- Sponsor
- Centre Hospitalier de Valenciennes
Blood Loss, Surgical
Tranexamic Acid for Total Knee Arthroscopy
The purpose of this investigation is to determine the most effective regimen of administration of tranexamic acid to improve clinical outcome among patients undergoing total knee arthroplasty.
- Trial name
- NCT04443920
- Testing
- Tranexamic acid (TXA)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- The Miriam Hospital
Arthroplasty, Knee Replacement, Replacement, Total Knee
ChloraPrep Versus Betadine for Elective Knee Replacement Surgery
This study will enroll patients who will be receiving primary total knee replacements. Subjects will be randomized into two groups: Betadine surgical scrub preparation and ChloraPrep preparation prior to total knee replacements.
- Conditions
- Arthroplasty, Knee Replacement, Replacement, Total Knee, Total Knee Replacement
- Trial name
- NCT01184196
- Testing
- Swab area with Betadine, Swab area with ChloraPrep
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Central DuPage Hospital