Clinical trials: Total Laparoscopic Hysterectomy, open to volunteers
Total Laparoscopic Hysterectomy
Routine Versus Selective Ureterolysis During Total Laparoscopic Hysterectomy for Benign Conditions
To evaluate whether routine ureterolysis during Total Laparoscopic Hysterectomy for benign gynecologic conditions affects operative efficiency and perioperative safety compared with a selective ureterolysis approach.
- Trial name
- NCT07774871
- Testing
- Routine Ureterolysis, Selective Ureterolysis
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- ClinAmygate
Total Laparoscopic Hysterectomy With Myoma Screw
Myoma Screw in Manipulation of Large Uterus in Total Laparoscopic Hysterectomy
To compare between myoma screw and uterine manipulator in manipulation of large uterus in total laparoscopic hysterectomy
- Trial name
- NCT06976905
- Testing
- Total laparoscopic hysterectomy
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Fibroid Uterus, Metrorrhagia
A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes
The goal of this randomized clinical trial is to assess the outcomes of total laparoscopic hysterectomy vs subtotal laparoscopic hysterectomy + mini-laparotomy for uterine extraction for benign gynecological conditions in terms…
- Conditions
- Fibroid Uterus, Metrorrhagia, Adenomyosis, Benign Gynecologic Neoplasm
- Trial name
- STORY (NCT06802198)
- Testing
- total hysterectomy, subtotal hysterectomy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pain, Postoperative
Long-acting Local Vaginal Cuff Anesthesia Following Hysterectomy
The purpose of this study is to compare recovery unit and post operation day (POD) 1 pain score in women following elective robotic assisted TLH (RA-TLH) for benign indication with and without local vaginal cuff injection of…
- Trial name
- LAVA (NCT07842159)
- Testing
- Combined Bupivacaine and Exparel, Normal Saline (NS)
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- The University of Texas Health Science Center, Houston
Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
POPQ Associated With Total Laparoscopic Hysterectomy
The goal of this observational study is to evaluate the impact of different hysterectomy (removal of the uterus) techniques on the risk of pelvic organ prolapse (situation when one or more of your pelvic organs like your bladder…
- Conditions
- Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle, Endometrial Hyperplasia, Pelvic Organ Prolapse (POP)
- Trial name
- POP-LAP (NCT07137299)
- Testing
- Questionnaire and Physical Exam
- Where
- 4 sites in Poland
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Silesia
Laparoscopic Hysterectomy
Total Laparoscopic Hysterectomy With Prior Uterine Artery Cauterization From the Origin Versus Conventional Laparoscopic Hysterectomy
The main goal of this study is to compare between total Laparoscopic hysterectomy proceeded by Uterine artery cauterization at its origin and conventional total Laparoscopic hysterectomy regarding: bleeding , operative time …
- Trial name
- NCT07601971
- Testing
- Total Laparoscopic hysterectomy with prior Uterine artery cauterization from the origin to arm 1, Conventional Laparoscopic hysterectomy to arm 2, Total Laparoscopic hysterectomy with conventional uterine artery ligation
- Volunteers
- 44 people
- Sponsor
- Kafrelsheikh University
Vaginal Cuff Complications
BARBED vs. STANDARD Suture for Colporrhaphy at the End of Laparoscopic Hysterectomy
Hysterectomy is one of the most common surgical procedures performed worldwide, with more than 400,000 hysterectomies performed annually in the United States.
- Trial name
- BARD (NCT05833204)
- Testing
- Laparoscopic colporrhaphy with 0-caliber barbed absorbable suture, Laparoscopic colporrhaphy with standard 0-caliber absorbable suture
- Where
- Italy
- Volunteers
- 1,614 people
- Sponsor
- Universita di Verona
Hysterectomy, Laparoscopic Surgery
Ureterolysis in Laparoscopic Total Hysterectomy: Routine Approach
This randomized controlled trial will compare routine bilateral ureterolysis with selective ureterolysis during total laparoscopic hysterectomy for benign gynecological conditions.
- Trial name
- ULTRA (NCT07774858)
- Testing
- Routine Ureterolysis, Selective Ureterolysis
- Where
- Egypt
- Volunteers
- 35,000 people
- Sponsor
- ClinAmygate
Total Laparoscopic Hysterectomy, Atelectasis, Postoperative
Effects of Ultrasound-guided Recruitment Manoeuvres on Postoperative Pulmonary Complications in OSA Patients Undergoing Total Laparoscopic Hysterectomy
This study aims to evaluate the lung-protective effects of ultrasound-guided lung recruitment maneuvers in patients with OSA undergoing total laparoscopic hysterectomy and to explore the efficacy of EELV measurement in assessing…
- Trial name
- NCT07362680
- Testing
- the sustained inflation recruitment maneuver, the incremental PEEP recruitment maneuver, the Ultrasound-guided recruitment maneuver
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Total Laparoscopic Hysterectomy
Laparoscopic Versus Transvaginal Closure of the Vaginal Vault After Total Laparoscopic Hysterectomy
The goal of this clinical trial is to compare the laparoscopic and transvaginal closure techniques of the vaginal vault in patients who perform TLH, regarding the risk of vaginal vault hematoma and other complications as vaginal…
- Trial name
- NCT06867614
- Testing
- Total laparoscopic hysterectomy
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams University
Post-operative Pain
Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy
The study is a single-center parallel group randomized controlled trial comparing the administration of a presacral nerve block using 20mL of local ropivacaine 5.0mg/ml versus 20mL of normal saline (sham block) on post-operative…
- Trial name
- NCT05953766
- Testing
- Ropivacaine injection, Normal saline injection
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Hysterectomy
Long-term Outcomes After Laparoscopic Subtotal and Total Hysterectomy
Hysterectomy is one of the most commonly performed gynecologic surgeries in the USA. It is used for many benign conditions such as leiomyoma and abnormal uterine bleeding.
- Trial name
- LAST-1 (NCT05421156)
- Testing
- Subtotal Laparoscopic Hysterectomy, Total Laparoscopic Hysterectomy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Postoperative Pain
Bupivacaine for Postoperative Pain After Laparoscopic Hysterectomy
This prospective, randomized, single-blind controlled study aims to evaluate the effect of bupivacaine injection at trocar entry sites and the vaginal cuff on postoperative pain in patients undergoing total laparoscopic…
- Trial name
- bupivacaine (NCT07435909)
- Testing
- Bupivacaine %0.5 (hyperbaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Serkan Kumbasar
Abnormal Uterine Bleeding, Endometriosis
Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic…
- Conditions
- Abnormal Uterine Bleeding, Endometriosis, Uterine Prolapse, Uterine Cancer
- Trial name
- BARHYSTER (NCT06024109)
- Testing
- Closure of the Vaginal Cuff after Total Hysterectomy
- Where
- 2 sites in Germany, Spain
- Volunteers
- 132 people
- Sponsor
- Aesculap AG
Endometrial Cancer
Comparison of Five-year Survival and Disease-free Survival in Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With and Without Uterine Manipulator
Comparison of five-year survival and disease-free survival in patients diagnosed with endometrium cancer who underwent total laparoscopic hysterectomy with and without a uterine manipulator
- Trial name
- NCT06307886
- Testing
- Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With manipulator, lPatients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy without uterine manipulator
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Endometriosis
ENDOmetriosis Robotic Assisted Surgery
The purpose of this study is to compare the robot-assisted approach with the laparoscopic approach in terms of reducing the rates of intraoperative and postoperative complications in patients undergoing total hysterectomy for DIE…
- Trial name
- ENDO-RAS (NCT06445179)
- Testing
- Total Laparoscopic Hysterectomy, Ureterolysis
- Where
- 2 sites in France
- Volunteers
- 224 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Benign Gynecologic Conditions
Comparison of the Outcomes of Total Laparoscopic Hysterectomy Versus Total Abdominal Hysterectomy for Benign Gynecologic Conditions in a Limited-resources Setting.
Minimally invasive hysterectomy (laparoscopic) is associated with shorter hospital stay, less blood loss, faster recovery, and improved early postoperative quality of life compared with open abdominal hysterectomy.
- Trial name
- NCT07496814
- Volunteers
- 32 people
- Sponsor
- Assiut University