Clinical trials: Total Vaginal Hysterectomy
Pelvic Organ Prolapse
Laparoscopic Hysterectomy With Vaginal Vault Suspension to the Uterosacral Ligaments for Stage II-III Pelvic Organ Prolapse.
The International Continence Society defines post-hysterectomy vault prolapse (PHVP) as descent of the vaginal cuff scar below a point that is 2 cm less than the total vaginal length above the plane of the hymen.
- Trial name
- LULS-1 (NCT03553511)
- Testing
- Vaginal vault suspension to the uterosacral ligaments, McCall culdoplasty
- Volunteers
- 60 people
- Sponsor
- Università degli Studi dell'Insubria
Laparoscopic Hysterectomy for Benign Conditions
Comparing Two Devices of Uterine Manipulation and Vaginal Fornix Delineation at Total Laparoscopic Hysterectomy
We hypothesize, that the use of the Hohl manipulator® at total laparoscopic hysterectomy reduces operative time (from skin incision to detachment of the uterus) and lateral termal damage of the vaginal wall during colpotomy due…
- Trial name
- NCT02197728
- Testing
- Use of the Colpo-Probe™ Vaginal Fornix Delineator or Hohl manipulator® during total laparoscopic hysterectomy
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- Unity Health Toronto
Preventative Laparoscopic Hysterectomy
Chlorhexidine vs Povidone Iodine Vaginal Prep in Decreasing Postoperative Infection in Total Laparoscopic Hysterectomy
This is a randomized control trial which will randomize patients who will be undergoing laparoscopic (conventional or robotic assisted) total hysterectomy to vaginal prep with 4% chlorhexidine gluconate vs 10% povidone iodine.
- Trial name
- NCT05692986
- Testing
- A vaginal swab for aerobic and anaerobic cultures before antibiotic administration, 30 minutes after vaginal prep and every hour thereafter until the surgery is completed.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
POPQ Associated With Total Laparoscopic Hysterectomy
The goal of this observational study is to evaluate the impact of different hysterectomy (removal of the uterus) techniques on the risk of pelvic organ prolapse (situation when one or more of your pelvic organs like your bladder…
- Conditions
- Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle, Endometrial Hyperplasia, Pelvic Organ Prolapse (POP)
- Trial name
- POP-LAP (NCT07137299)
- Testing
- Questionnaire and Physical Exam
- Where
- 4 sites in Poland
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Silesia
Total Laparoscopic Hysterectomy
Zip-Stitch™ for Vaginal Cuff Closure in Total Laparoscopic Hysterectomy
ZSX Medical completed enrollment in its First in Human Ease of Use study in May of 2017, in Monterrey Mexico. The purpose of this study is to demonstrate the ease of use of Zip-Stitch™, to generate first in human data, and to…
- Trial name
- NCT03310658
- Testing
- Zip-Stitch Soft Tissue Closure System
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- ZSX Medical LLC
Total Laparoscopic Hysterectomy, Benign Conditions
Comparison of Two Methods of Vaginal Cuff Closure at Laparoscopic Hysterectomy
American Congress of Obstetricians and Gynecologists (ACOG) advises minimally invasive methods in gynecological surgery to ensure increased benefits to the patient and reduce potential hospitalization costs.
- Trial name
- NCT02293369
- Testing
- Cuff closure via vaginal route, Cuff closure via laparoscopic route
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Istanbul University
Same Day Discharge, Pelvic Organ Prolapse
Same Day Discharge Following Pelvic Reconstructive Surgery
This is a prospective cross-sectional study in which patients undergoing major pelvic reconstructive surgery with total vaginal hysterectomy will be recruited and enrolled.
- Conditions
- Same Day Discharge, Pelvic Organ Prolapse, Total Vaginal Hysterectomy
- Trial name
- NCT04804826
- Testing
- Pelvic Reconstructive Surgery
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- TriHealth Inc.
Vaginal Cuff Complications
BARBED vs. STANDARD Suture for Colporrhaphy at the End of Laparoscopic Hysterectomy
Hysterectomy is one of the most common surgical procedures performed worldwide, with more than 400,000 hysterectomies performed annually in the United States.
- Trial name
- BARD (NCT05833204)
- Testing
- Laparoscopic colporrhaphy with 0-caliber barbed absorbable suture, Laparoscopic colporrhaphy with standard 0-caliber absorbable suture
- Where
- Italy
- Volunteers
- 1,614 people
- Sponsor
- Universita di Verona
Total Laparoscopic Hysterectomy
Laparoscopic Versus Transvaginal Closure of the Vaginal Vault After Total Laparoscopic Hysterectomy
The goal of this clinical trial is to compare the laparoscopic and transvaginal closure techniques of the vaginal vault in patients who perform TLH, regarding the risk of vaginal vault hematoma and other complications as vaginal…
- Trial name
- NCT06867614
- Testing
- Total laparoscopic hysterectomy
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams University
Postoperative Pain
Bupivacaine for Postoperative Pain After Laparoscopic Hysterectomy
This prospective, randomized, single-blind controlled study aims to evaluate the effect of bupivacaine injection at trocar entry sites and the vaginal cuff on postoperative pain in patients undergoing total laparoscopic…
- Trial name
- bupivacaine (NCT07435909)
- Testing
- Bupivacaine %0.5 (hyperbaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Serkan Kumbasar
Pelvic Organ Prolapse
Randomized,Multicentric Study to Treat Prolapse After Hysterectomy With Amreich Procedure or Total Prolift Procedure
Head to Head comparison of perioperative complications and secondary the impact of operation techniques with or without mesh on patients suffering from pelvic organ prolapse on quality of life.
- Trial name
- NCT00572702
- Testing
- Vaginal fixation Amreich-Richter, Prolift total
- Where
- 5 sites in Czechia
- Volunteers
- 200 people
- Sponsor
- Charles University, Czech Republic
Infection, Bleeding
Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy ( ISTIAB-0)
Total hysterectomy is one of the most performed surgical procedures in the world and it is associated with post-operative complications.
- Conditions
- Infection, Bleeding, Complication, Postoperative
- Trial name
- ISTIAB-0 (NCT03791294)
- Testing
- TIAB: microcrystalline titanium dioxide with covalently linked monovalent silver ions
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Vaginal Vault Prolapse, Sexual Function
Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy
The purpose of this study is to assess the feasibility of performing prophylactic McCall culdoplasty at the time of total laparoscopic hysterectomy.
- Trial name
- NCT01840176
- Testing
- McCall culdoplasty
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pelvic Organ Prolapse
Permanent Versus Absorbable Colpopexy Trial
Primary Aim: The primary aim of this randomized controlled trial (RCT) is to compare vaginal mesh and suture exposure rates in women undergoing robotic total hysterectomy and sacrocolpopexy with a light-weight polypropylene mesh…
- Trial name
- PACT (NCT02277925)
- Testing
- Polytetrafluoroethylene, Polydioxanone
- Where
- 5 sites in United States
- Volunteers
- 204 people
- Sponsor
- University of North Carolina, Chapel Hill
Prolapse, Vaginal, Vaginal Vault Prolapse
Post-Hysterectomy Vaginal Length: Horizontal vs. Vertical Closure
This prospective clinical study aims to evaluate the impact of vaginal cuff closure orientation-horizontal versus vertical-on postoperative total vaginal length in patients undergoing vaginal hysterectomy combined with lateral…
- Trial name
- vagina (NCT07067645)
- Testing
- Horizontal Vaginal Cuff Closure Technique, Vertical Vaginal Cuff Closure Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Febrile Morbidity
Vaginal Douching and Painting in Women Who Underwent Total Abdominal Hysterectomy
Comparison of the effectiveness of povidone-iodine douching and painting for reducing febrile morbidity after total abdominal hysterectomy
- Trial name
- NCT03537313
- Testing
- Vagina douching, Vagina painting
- Where
- Thailand
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand