Clinical trials: Tourette's Syndrome
Tourette Syndrome
SCI-110 in the Treatment of Tourette Syndrome
To evaluate the efficacy, safety and tolerability of the cannabinoid-based medication SCI-110 compared to placebo in subjects with Tourette syndrome.
- Trial name
- NCT05126888
- Testing
- SCI-110
- Where
- 3 sites in United States, Germany and 1 more
- Volunteers
- 164 people
- Sponsor
- Neurothera Labs Inc.
Tic Disorder, Chronic Motor or Vocal, Tourette Syndrome in Children
Evaluation of a Cognitive Psychophysiological Treatment for Tourette Syndrome and Tic Disorders
It is a randomized controlled trial to compare two behavioural treatments, namely CBIT and CoPs. This study would be the first head-to-head randomized trial between two established treatments rather than supportive counseling or…
- Conditions
- Tic Disorder, Chronic Motor or Vocal, Tourette Syndrome in Children, Tourette Syndrome
- Trial name
- NCT03225430
- Testing
- Cognitive behavioural treatment for tics, Cognitive psychophysiological
- Where
- Canada
- Volunteers
- 144 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Tourette's Disorder
ABF Tourette's Disorder Post Marketing Surveillance Study
This is a Post-Marketing Surveillance study of Abilify® tablets in accordance with Korean regulations on New Drug Re-examination (i.e. New Drug Re-examination Standards: KFDA Notification No. 2010-94 dated 27 December 2010).
- Trial name
- NCT01795105
- Where
- 4 sites in South Korea
- Volunteers
- 692 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Tourette Syndrome, ADHD
Modified Comprehensive Behavioral Intervention for Tics (M_CBIT)
The main purpose of this trial is to develop and investigate the effects of a modified comprehensive behavioral intervention for tics (CBIT) protocol for children and adolescents with chronic tic disorders and ADHD.
- Trial name
- M_CBIT (NCT02900144)
- Testing
- Modified Comprehensive Behavioral Intervention for Tics, Comprehensive Behavioral Intervention for Tics
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Massachusetts General Hospital
Tourette's Syndrome, Chronic Motor Tic Disorder
Brain Activation in Vocal and Motor Tics
This study will investigate the brain areas that are activated by vocal and motor tics in patients with Tourette's syndrome and other tic disorders. Tics are involuntary repetitive movements similar to voluntary movements.
- Conditions
- Tourette's Syndrome, Chronic Motor Tic Disorder, Chronic Motor Vocal Disorder
- Trial name
- NCT00026000
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder)
Epidiolex in Obsessive Compulsive Disorder and Related Disorders
The primary objective of the proposed study is to evaluate the safety and efficacy of Epidiolex (cannabidiol) in adults with obsessive compulsive and related disorders (OCRDs).
- Conditions
- Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder), Tourette Syndrome, Hoarding Disorder
- Trial name
- NCT04978428
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Chicago
Tic Disorders
Efficacy of Amoxicilline/Clavulanic Acid in Patients Affected by Tic Disorder Colonized by Group A Streptococcus
This study is an extension of the European Multicentre Tics In Children Studies (EMTICS) COURSE study for which a separate study protocol exists; Aim of this clinical trial is to study the efficacy of treatment with antibiotics…
- Trial name
- AntibioTICS (NCT01860300)
- Testing
- Amoxicillin-Potassium Clavulanate Combination
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Roma La Sapienza
Tourette Syndrome
Safety and Efficacy Study of NBI-98854 in Children and Adolescents With Tourette Syndrome
Phase 2, double-blind, placebo-controlled study to assess the safety and efficacy of NBI-98854 administered once daily (qd) for a total of 6 weeks of treatment.
- Trial name
- NCT02679079
- Testing
- NBI-98854
- Where
- 44 sites in United States
- Volunteers
- 98 people
- Sponsor
- Neurocrine Biosciences
Tourette Syndrome
Atomoxetine in Patients With Tourette's Syndrome
The purpose of this pilot study is to evaluate the effects of Atomoxetine, a selective noradrenaline reuptake inhibitor, on impulsivity in patients with Tourette's syndrome.
- Trial name
- ATO-TS (NCT04354103)
- Testing
- Atomoxetine
- Where
- 3 sites in France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Anorexia Nervosa, Obsessive Compulsive Disorder
Evaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions
The purpose of this study is to better understand the long-term progress of people with obsessive-compulsive disorder (OCD) and related conditions such as anorexia nervosa, Tourette syndrome, and trichotillomania.
- Conditions
- Anorexia Nervosa, Obsessive Compulsive Disorder, Tourette Syndrome, Trichotillomania
- Trial name
- NCT00004550
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Mental Health (NIMH)
Tourette Syndrome, Motor or Vocal Tic Disorder, Chronic
Group Intervention for Children With Chronic Tics Syndrome or Tourette Syndrome: CBIT vs Psycho-Educational Intervention
Tourette Syndrome (TS) is a disorder characterized by motor and vocal tics. The most studied and promising intervention is Habit Reversal Training (HRT) and its variations: Behavioral Comprehensive Intervention for Tics (CBIT).
- Trial name
- NCT02407951
- Testing
- CBIT group, Psycho-Educational group
- Volunteers
- 96 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Tourette Syndrome
Multi-site Transcranial Magnetic Stimulation Therapy of the Supplementary Motor Area in Children With Tourette Syndrome
The investigators are investigating the effectiveness of a wearable multisite transcranial magnetic stimulation (mTMS) device that can deliver stimuli at multiple cortical sites simultaneously or sequentially for the treatment of…
- Trial name
- NCT03642951
- Testing
- Active Treatment
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Tourette Syndrome, Tic Disorders
CANNAbinoids in the Treatment of TICS (CANNA-TICS)
This is a multicentre, randomized, double-blind, placebo controlled, parallel-group, phase IIIb trial. Patients (≥18 years) with chronic tic disorders and Tourette syndrome will be recruited.
- Trial name
- CANNA-TICS (NCT03087201)
- Testing
- nabiximols
- Where
- 6 sites in Germany
- Volunteers
- 98 people
- Sponsor
- Hannover Medical School
Tourette Syndrome
Randomized Study of Pergolide in Children With Tourette Syndrome
OBJECTIVES: I. Evaluate the presumed mechanism of action of low dose pergolide to act acutely through the dopaminergic autoreceptor or postsynaptically at D2 sites in children 7 to 17 with tourette syndrome (GTS). II.
- Trial name
- NCT00004433
- Testing
- pergolide
- Volunteers
- 74 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Tourette Syndrome
The Effect and Safety of Plum-blossom Needle for Tourette Syndrome
To evaluate the effect and safety of plum-blossom needle for Tourette syndrome.
- Trial name
- NCT02403258
- Testing
- Plum-blossom needle group, HRT group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Tourette Syndrome
MRI Study of Tic Remission in Tourette Syndrome
Doctors provide a ray of hope to children and their parents with the knowledge that, for most patients, symptoms of Tourette syndrome improve by the time they are young adults.
- Trial name
- NCT01405859
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Utah
Tic-Disorder
Efficacy of a Resources Activation Treatment on Tic-symptoms
The main purpose of this study is to evaluate the efficacy of a resources activation based treatment programme in children and adolescents aged 8 to 18 years with tic disorders.
- Trial name
- NCT02190370
- Testing
- Resources activation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Cologne
Tourette Syndrome, Tic Disorders
A Handwriting Intervention Program for Children With Tic Disorders
The purpose of this study is to evaluate the effectiveness of a computerized handwriting training protocol (MovAlyzeR), through daily practice of handwriting on an electronic device to improve handwriting skills in children with…
- Trial name
- NCT04246112
- Testing
- Handwriting intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Alabama at Birmingham
Tourette Syndrome
Rollover Study for Continuing NBI-98854 Administration in Pediatric Subjects With Tourette Syndrome
This is an open-label, rollover study to collect long-term safety, tolerability, and investigator- and participant-reported pharmacodynamic (PD) data after chronic administration of NBI-98854 in pediatric participants with…
- Trial name
- NCT03732534
- Testing
- NBI-98854
- Where
- 10 sites in United States, Puerto Rico
- Volunteers
- 6 people
- Sponsor
- Neurocrine Biosciences
Tourette's Disorder
Investigating Circadian Rhythms in Youth With Persistent Tic Disorders
This study examines circadian rhythms and morningness-eveningness preference in youth with Persistent Tic Disorders (PTDs), including Tourette's Disorder (TD); and assesses the effects of wearable short wavelength light therapy…
- Trial name
- NCT03508245
- Testing
- Wearable short wavelength light therapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, Los Angeles