Clinical trials: Tourniquet
Amputation, PTSD
Evacuation Time and Tourniquet Use as Risk Factors for PTSD in Combat-Related Amputation
This study aims to evaluate the relationship between evacuation time, tourniquet use, and the development of post-traumatic stress disorder (PTSD) in patients with combat-related amputations.
- Conditions
- Amputation, PTSD, Combat Posttraumatic Stess Disorder, Combat Trauma
- Trial name
- EVAC-PTSD Stud (NCT07502313)
- Where
- Ukraine
- Volunteers
- 300 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Ankle Fractures, Ankle Fracture - Lateral Malleolus
Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery
This study aims to 1) characterize skeletal muscle pH during/after tourniquet use and 2) investigate any relationship between intraoperative tourniquet use and postoperative functional measures and patient-reported outcomes.
- Conditions
- Ankle Fractures, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar
- Trial name
- NCT05445960
- Testing
- Tourniquet
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Oregon Health and Science University
Tourniquet Palsy
Tourniquet in Total Knee Replacement Short and Long Duration: A Comparative Study
Total knee arthroplasty (TKA) is an effective treatment in severe osteoarthritis. We aim to compare the advantages and disadvantages related to the duration of tourniquet application in TKA surgeries.
- Trial name
- NCT06521593
- Testing
- Applying a tourniquet for either a short or long time during total knee replacement
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Quadriceps Muscle Atrophy, Tourniquet
Evaluation of Ischemia and Reperfusion Interval With Neuromonitorization in Tourniquet Application
The goal of this clinical trial is to compare two differential tourniquet pressure in lower extremity surgery cases. The main questions it aims to answer are: What are the perioperative neurophysiological effects of ischemia and…
- Conditions
- Quadriceps Muscle Atrophy, Tourniquet, EMG
- Trial name
- NCT05926154
- Testing
- Surgical tourniquet pressure selection
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul University
Surgery, Anesthesia, Local
Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures
The purpose of this study is to determine whether eating solid food prior to undergoing a wide awake local-only no tourniquet (WALANT) procedure reduces anxiety in patients or has any effect on outcomes.
- Conditions
- Surgery, Anesthesia, Local, Fasting
- Trial name
- NCT05819801
- Testing
- Non-fasting, Fasting
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- University of California, Irvine
Application Site Discomfort, Medical Device Discomfort
Control of Tourniquet Pain With an Axillary Ring of Subcutaneous Local Anesthetic
Purpose: Even with excellent regional anesthesia of the upper extremity, tourniquet (Tq) pain from an upper arm Tq can limit the ability to use regional anesthesia as the primary anesthetic for surgical procedures on the upper…
- Trial name
- NCT01829399
- Testing
- Bupivacaine with Epinephrine, Normal Saline
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Knee Osteoarthritis, Arthropathy of Knee Joint
Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia
Previous retrospective database studies suggest that total knee arthroplasty (TKA) surgery under spinal anesthesia has less complications than when performed under general anesthesia.
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee Joint, Knee Pain Chronic, Rheumatoid Arthritis
- Trial name
- NCT03364088
- Testing
- Spinal anesthesia with tourniquet, Spinal anesthesia without tourniquet, General anesthesia with tourniquet
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Riku Antero Palanne
Catheterization, Peripheral, Venous Dilatation
The Effect of Tapping in the Venous Dilatation for Peripheral IV Access
Peripheral intravenous cannulation (PIVC) is one of the most common interventions in medical practice. Venous dilatation is helpful for successful PIV placement.
- Trial name
- Tapping (NCT05265481)
- Testing
- Tourniquet, Manual Tapping, Device tapping
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Florida
Post Operative Hemorrhage
Intravenous Tranexamic Acid Versus Pericervical Tourniquet To Decrease Blood Loss In Trans-Abdominal Myomectomy
Intravenous Tranexamic Acid Versus Pericervical Tourniquet To Decrease Blood Loss In Trans-Abdominal Myomectomy
- Trial name
- NCT02733952
- Testing
- Tranexamic Acid, Pericervical Tourniquet
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams Maternity Hospital
Superficial Forearm Veins Compressibility and Width
Effect of Double Tourniquet Technique on Ultrasonographic View of Forearm Veins
Vein compressibility will be assessed after light pressure applied with the ultrasound probe. Vein compressibility will be graded as 3 (100% compressed), 2 (50-100 compressed), and 1 (less than 50% compressed).
- Trial name
- NCT04613011
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bahaa Mohammed Refaie
Carpal Tunnel Syndrome
WALANT Versus Local Anesthesia With Tourniquet for Carpal Tunnel Decompression
This multicenter, randomized, double-blinded controlled trial compared two local anesthetic techniques for open carpal tunnel decompression in adults.
- Trial name
- WALANT vs LA-T (NCT07617064)
- Testing
- WALANT technique for carpal tunnel decompression, Local anesthesia with tourniquet for carpal tunnel decompression
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Misr University for Science and Technology
Blood Flow Restriction (BFR) Training Effects
Quantification of Progenitor Cell Circulation Following Vascular Resistance Exercise Using Delfi Tourniquet System
The purpose of this observational study is to examine how slowing down blood flow to the legs- a practice called blood flow restriction (BFR)- during exercise by applying compression to the legs affects the way stem cells are…
- Trial name
- NCT07213726
- Testing
- Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Andrews Research & Education Foundation
Blood Pressure
Tourniquets Increase Proximal Pressure
There is an urgent clinical need to improve survival and neurologic outcomes after cardiac arrest. When a patient goes into cardiac arrest, cardiopulmonary resuscitation (CPR) with chest compressions is the current standard of…
- Trial name
- NCT05324306
- Testing
- combat application tourniquets (CAT)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Hypospadias Repair
Hemostasis During Hypospadias Surgery
A comparison between the two hemostatic methods of hypospadias repairing operation, in terms of early and mid-term (up to 6 months) failure rate (wound dehiscence and urethral stricture needing reoperation) between the two…
- Trial name
- NCT02268019
- Testing
- tourniquet application, epinephrine injection
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
Osteoarthritis
Outcomes Following Tourniquet and Non-Tourniquet Assisted Total Knee Arthroplasty
The overall goal of this study is to determine the effects of intraoperative tourniquet use during total knee arthroplasty (TKA), compared to TKA without the use of a tourniquet (NOTQT), for strength and functional recovery…
- Trial name
- NCT02203045
- Testing
- Total Knee Arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Colorado, Denver
Complications; Arthroplasty
A Comparison Between an Individual Low Tourniquet Pressure Versus a Standard Pressure During Total Knee Arthroplasty
The use of bloodless field is a helpful and important method in orthopedic surgery. The surgery can be done without interrupting bleedings, while keeping an exact overlook of the anatomy.
- Trial name
- NCT01442298
- Testing
- Limb occlusion pressure (LOP), conventional measurement method
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Charlotta Olivecrona
Hemorrhage, Hypovolemic Shock
Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs
The goal of this clinical trial is to compare the occlusive capability and mechanical behavior of different commercially available pre-hospital tourniquet models and the results of their application on upper and lower limbs, in…
- Conditions
- Hemorrhage, Hypovolemic Shock, Tourniquets
- Trial name
- TQ-BR (NCT06725602)
- Testing
- TQ - Proximal Application ("high and tight"), TQ - Controlled application (2-3 inches)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Laparoscopic Liver Resection, Vascular Occlusion
Bulldog vs. Cotton Tourniquet in Laparoscopic Hepatectomy for Patients
LLR was applied for tumors located at the lower edge and lateral segments of the liver that could be resected more easily than posterosuperior segments.
- Conditions
- Laparoscopic Liver Resection, Vascular Occlusion, Tourniquet
- Trial name
- NCT04277065
- Testing
- BULLDOG ,A Useful Vascular Occlusion Tourniquet In Laparoscopic Liver Resection, cotton tourniquet
- Where
- China
- Volunteers
- 88 people
- Sponsor
- hui hou
Tourniquet Safety and Effectiveness
A New Technique for Determining Limb Occlusion Pressure
This study evaluates a novel technique for measuring the minimum pressure necessary to achieve a bloodless surgical field, known as a patient's limb occlusion pressure (LOP).
- Trial name
- NCT02620722
- Testing
- Personalized Tourniquet Instrument, Handheld Doppler ultrasound
- Where
- 4 sites in Canada
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Initial Systolic Blood Pressure (mmHg), Arterial Occlusion Pressure (mmHg)
Does Anesthetic Technique Affect Pneumatic Tourniquet Pressures in Upper Limb Fracture Surgery?
In pneumatic tourniquet applications, the use of an individualized, lowest-effective tourniquet pressure (TP) has been recommended, in order to avoid pressure related complications.
- Conditions
- Initial Systolic Blood Pressure (mmHg), Arterial Occlusion Pressure (mmHg), Tourniquet Time (Minutes), Quality of Bloodless Surgical Field (4 Point Scale)
- Trial name
- NCT04710225
- Testing
- Upper limb fracture surgery and arterial occlusion pressure (AOP) estimation based tourniquet pressure (TP) setting
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Baskent University Ankara Hospital